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Statistical analysis of magnetic resonance imaging (MRI) can help radiologists to detect pathologies that are otherwise likely to be missed. Deep learning (DL) has shown promise in modeling complex spatial data for brain anomaly detection.…

Objectives: High classification accuracy of Alzheimer's disease (AD) from structural MRI has been achieved using deep neural networks, yet the specific image features contributing to these decisions remain unclear. In this study, the…

Alzheimers disease (AD) is a severe neurological brain disorder. It is not curable, but earlier detection can help improve symptoms in a great deal. The machine learning based approaches are popular and well motivated models for medical…

Age prediction based on Magnetic Resonance Imaging (MRI) data of the brain is a biomarker to quantify the progress of brain diseases and aging. Current approaches rely on preparing the data with multiple preprocessing steps, such as…

The automated detection of cancerous tumors has attracted interest mainly during the last decade, due to the necessity of early and efficient diagnosis that will lead to the most effective possible treatment of the impending risk. Several…

Deep Convolutional Neural Networks (CNNs) i.e. Residual Networks (ResNets) have been used successfully for many computer vision tasks, but are difficult to scale to 3D volumetric medical data. Memory is increasingly often the bottleneck…

Motivation. While recent studies show high accuracy in the classification of Alzheimer's disease using deep neural networks, the underlying learned concepts have not been investigated. Goals. To systematically identify changes in brain…

Deep convolutional neural networks (CNNs) are state-of-the-art for semantic image segmentation, but typically require many labeled training samples. Obtaining 3D segmentations of medical images for supervised training is difficult and labor…

Many functional and structural neuroimaging studies call for accurate morphometric segmentation of different brain structures starting from image intensity values of MRI scans. Current automatic (multi-) atlas-based segmentation strategies…

Improving patient outcomes depends on the prompt and accurate diagnosis of brain tumors, but manual MRI scan analysis is still time-consuming and unreliable. Although deep learning has shown promise, many of the models that are now in use…

Convolutional Neural Networks (CNN) have emerged as powerful tools for learning discriminative image features. In this paper, we propose a framework of 3-D fully CNN models for Glioblastoma segmentation from multi-modality MRI data. By…

Alzheimer's disease (AD) is associated with local (e.g. brain tissue atrophy) and global brain changes (loss of cerebral connectivity), which can be detected by high-resolution structural magnetic resonance imaging. Conventionally, these…

In this work we propose an adversarial learning approach to generate high resolution MRI scans from low resolution images. The architecture, based on the SRGAN model, adopts 3D convolutions to exploit volumetric information. For the…

Deep learning shows high potential for many medical image analysis tasks. Neural networks can work with full-size data without extensive preprocessing and feature generation and, thus, information loss. Recent work has shown that the…

We propose a novel framework for Alzheimer's disease (AD) detection using brain MRIs. The framework starts with a data augmentation method called Brain-Aware Replacements (BAR), which leverages a standard brain parcellation to replace…

The transition from mild cognitive impairment (MCI) to Alzheimer's disease (AD) is of great interest to clinical researchers. This phenomenon also serves as a valuable data source for quantitative methodological researchers developing new…

Recent evidence has shown that structural magnetic resonance imaging (MRI) is an effective tool for Alzheimer's disease (AD) prediction and diagnosis. While traditional MRI-based diagnosis uses images acquired at a single time point, a…

The identification of Alzheimer's disease (AD) and its early stages using structural magnetic resonance imaging (MRI) has been attracting the attention of researchers. Various data-driven approaches have been introduced to capture subtle…

The health and function of tissue rely on its vasculature network to provide reliable blood perfusion. Volumetric imaging approaches, such as multiphoton microscopy, are able to generate detailed 3D images of blood vessels that could…

The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic…