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Restrictions to molecular motion by barriers (membranes) are ubiquitous in biological tissues, porous media and composite materials. A major challenge is to characterize the microstructure of a material or an organism nondestructively using…

Soft Condensed Matter · Physics 2011-03-11 Dmitry S. Novikov , Els Fieremans , Jens H. Jensen , Joseph A. Helpern

We study two mechanisms for the formation of protein patterns near membranes of living cells by mathematical modelling. Self-assembly of protein domains by electrostatic lipid-protein interactions is contrasted with self-organization due to…

Cell Behavior · Quantitative Biology 2007-05-23 Karin John , Markus Baer

In a cellular medium, the plasmic membrane is a place of interactions between the cell and its direct external environment. A classic model describes it as a fluid mosaic. The fluid phase of the membrane allows a lateral degree of freedom…

Probability · Mathematics 2013-09-24 Aimé Lachal

Multicomponent lipid mixtures exhibit complex phase behavior, including coexistence of nanoscopic fluid phases in ternary mixtures mimicking the composition of the outer leaflet of mammalian plasma membrane. The physical mechanisms…

Soft Condensed Matter · Physics 2011-06-01 Frederick A. Heberle , Gerald W. Feigenson

We introduce a two-state non-conserving driven-diffusive system in one-dimension under a discrete-time updating scheme. We show that the steady-state of the system can be obtained using a matrix product approach. On the other hand, the…

Statistical Mechanics · Physics 2014-03-07 S. R. Masharian , F. H. Jafarpour , A. Aghamohammadi

Hydrodynamics is known to have strong effects on the kinetics of phase separation. There exist open questions on how such effects manifest in systems under confinement. Here, we have undertaken extensive studies of the kinetics of phase…

Soft Condensed Matter · Physics 2025-11-03 Saikat Basu , Suman Majumder , Raja Paul , Subir K. Das

We address the problem of the microscopic reorganization of a granular medium under a compaction process in the framework of Tetris-like models. We point out the existence of regions of spatial organization which we call domains, and study…

Statistical Mechanics · Physics 2009-11-07 A. Baldassarri , S. Krishnamurthy , V. Loreto , S. Roux

The internal structure of domains smaller than the characteristic size in domain coarsening dynamics of $Z_2$ symmetry breaking is evaluated theoretically for different phase ordering systems in two dimensions. In the previous works on…

Statistical Mechanics · Physics 2019-07-04 Hiromitsu Takeuchi

Conservative and non-conservative phase-field models are considered for the numerical simulation of lateral phase separation and coarsening in biological membranes. An unfitted finite element method is devised for these models to allow for…

Numerical Analysis · Mathematics 2019-01-08 Vladimir Yushutin , Annalisa Quaini , Sheereen Majd , Maxim Olshanskii

The large scale behaviour of a population of cells that grow and interact through the concentration field of the chemicals they secrete is studied using dynamical renormalization group methods. The combination of the effective long-range…

Cell Behavior · Quantitative Biology 2015-01-19 Anatolij Gelimson , Ramin Golestanian

Plastic rearrangements play a crucial role in the characterization of soft-glassy materials, such as emulsions and foams. Based on numerical simulations of soft-glassy systems, we study the dynamics of plastic rearrangements at the…

Soft Condensed Matter · Physics 2014-10-27 R. Benzi , M. Sbragaglia , A. Scagliarini , P. Perlekar , M. Bernaschi , S. Succi , F. Toschi

The domain-area distribution in the phase transition dynamics of ${\rm Z}_2$ symmetry breaking is studied theoretically and numerically for segregating binary Bose--Einstein condensates in quasi-two-dimensional systems. Due to the dynamic…

Quantum Gases · Physics 2018-01-18 Hiromitsu Takeuchi

Domains walls and topological defects in ferroelectric materials have emerged as a powerful new paradigm for functional electronic devices including memory and logic. Similarly, wall interactions and dynamics underpin a broad range of…

There are many natural, physical, and biological systems that exhibit multiple time scales. For example, the dynamics of a population of ticks can be described in continuous time during their individual life cycle yet discrete time is used…

Dynamical Systems · Mathematics 2009-07-10 Raquel M. Lopez , Sergei K. Suslov , Erika T. Camacho

This work introduces a semi-analytical frequency-domain framework for the analysis of two-dimensional, time-modulated (2+1)-D metasurfaces controlled by PIN diodes. The formulation focuses on the unit-cell level, modeled as a waveguide…

The domain formation of curvature-inducing molecules, such as peripheral or transmembrane proteins and conical surfactants, is studied in thermal equilibrium and nonequilibrium steady states using meshless membrane simulations. These…

Soft Condensed Matter · Physics 2023-01-30 Hiroshi Noguchi

Mechanical cues from the extracellular microenvironment play a central role in regulating the structure, function and fate of living cells. Nevertheless, the precise nature of the mechanisms and processes underlying this crucial cellular…

Biological Physics · Physics 2015-06-23 Ariel Livne , Eran Bouchbinder , Benjamin Geiger

Various rod-shaped bacteria such as the canonical gram negative Escherichia coli or the well-studied gram positive Bacillus subtilis divide symmetrically after they approximately double their volume. Their size at division is not constant,…

Cell Behavior · Quantitative Biology 2015-06-18 Ariel Amir

Discrete time crystals represent a paradigmatic nonequilibrium phase of periodically driven matter. Protecting its emergent spatiotemporal order necessitates a mechanism that hinders the spreading of defects, such as localization of domain…

Statistical Mechanics · Physics 2022-09-16 Mario Collura , Andrea De Luca , Davide Rossini , Alessio Lerose

Proteins and nucleic acids can spontaneously self-assemble into membraneless droplet-like compartments, both in vitro and in vivo. A key component of these droplets are multi-valent proteins that possess several adhesive domains with…

Biomolecules · Quantitative Biology 2020-01-10 Srivastav Ranganathan , Eugene Shakhnovich