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Isotonic regression (IR) is shape-constrained regression to maintain a univariate fitting curve non-decreasing, which has numerous applications including single-index models and probability calibration. When it comes to multi-output…

Machine Learning · Statistics 2026-03-12 Han Bao , Amirreza Eshraghi , Yutong Wang

Isotonic distributional regression (IDR) is a powerful nonparametric technique for the estimation of conditional distributions under order restrictions. In a nutshell, IDR learns conditional distributions that are calibrated, and…

Methodology · Statistics 2021-09-29 Alexander Henzi , Johanna F. Ziegel , Tilmann Gneiting

We introduce Conformal Interquantile Regression (CIR), a conformal regression method that efficiently constructs near-minimal prediction intervals with guaranteed coverage. CIR leverages black-box machine learning models to estimate outcome…

Machine Learning · Statistics 2026-01-07 Naixin Guo , Rui Luo , Zhixin Zhou

In observational studies, potential confounders may distort the causal relationship between an exposure and an outcome. However, under some conditions, a causal dose-response curve can be recovered using the G-computation formula. Most…

Methodology · Statistics 2019-12-18 Ted Westling , Peter Gilbert , Marco Carone

This article introduces a new nonparametric method for estimating a univariate regression function of bounded variation. The method exploits the Jordan decomposition which states that a function of bounded variation can be decomposed as the…

Statistics Theory · Mathematics 2016-08-11 Arnaud Guyader , Nick Hengartner , Nicolas Jégou , Eric Matzner-Løber

Isotonic regression is a nonparametric approach for fitting monotonic models to data that has been widely studied from both theoretical and practical perspectives. However, this approach encounters computational and statistical overfitting…

Methodology · Statistics 2012-03-21 Ronny Luss , Saharon Rosset , Moni Shahar

We consider the problem of estimating a dose-response curve. Continuous treatments arise often in practice, e.g. in the form of time spent on an operation, distance traveled to a location or dosage of a drug. Letting $A$ denote a continuous…

Methodology · Statistics 2026-04-14 Matteo Bonvini , Edward H. Kennedy

Isotonic regression is a shape-constrained nonparametric regression in which the regression is an increasing step function. For $n$ data points, the number of steps in the isotonic regression may be as large as $n$. As a result, standard…

Computation · Statistics 2014-12-10 Janis Hardwick , Quentin F. Stout

Supervised dimension reduction (SDR) has been a topic of growing interest in data science, as it enables the reduction of high-dimensional covariates while preserving the functional relation with certain response variables of interest.…

Machine Learning · Statistics 2023-05-23 Sam Hawke , Hengrui Luo , Didong Li

Motivated by global warming issues, we consider a time se- ries that consists of a nondecreasing trend observed with station- ary fluctuations, nonparametric estimation of the trend under monotonicity assumption is considered. The rescaled…

Statistics Theory · Mathematics 2008-12-18 Ou Zhao , Michael Woodroofe

Iterative refinement (IR) is a popular scheme for solving a linear system of equations based on gradually improving the accuracy of an initial approximation. Originally developed to improve upon the accuracy of Gaussian elimination,…

Numerical Analysis · Mathematics 2025-06-24 Chai Wah Wu , Mark S. Squillante , Vasileios Kalantzis , Lior Horesh

This paper studies the estimation and inference for the isotonic regression at the boundary point, an object that is particularly interesting and required in the analysis of monotone regression discontinuity designs. We show that the…

Statistics Theory · Mathematics 2020-12-22 Andrii Babii , Rohit Kumar

Group sequential designs in clinical trials allow for interim efficacy and futility monitoring. Adjustment for baseline covariates can increase power and precision of estimated effects. However, inconsistently applying covariate adjustment…

Methodology · Statistics 2023-08-11 Marlena S. Bannick , Sonya L. Heltshe , Noah Simon

Understanding the dose-response relation between a continuous treatment and the outcome for an individual can greatly drive decision-making, particularly in areas like personalized drug dosing and personalized healthcare interventions.…

Machine Learning · Computer Science 2026-01-07 Jarne Verhaeghe , Jef Jonkers , Sofie Van Hoecke

Compressive-sensing-based uncertainty quantification methods have become a pow- erful tool for problems with limited data. In this work, we use the sliced inverse regression (SIR) method to provide an initial guess for the alternating…

Numerical Analysis · Mathematics 2018-09-11 Xiu Yang , Weixuan Li , Alexandre Tartakovsky

Sliced inverse regression (SIR) is a popular sufficient dimension reduction method that identifies a few linear transformations of the covariates without losing regression information with the response. In high-dimensional settings, SIR can…

Methodology · Statistics 2025-12-04 Linh H. Nghiem , Francis. K. C. Hui , Samuel Muller , A. H. Welsh

For robust statistical inference it is crucial to obtain a good estimator of the variance of the proposed estimator of the statistical estimand. A commonly used estimator of the variance for an asymptotically linear estimator is the sample…

Methodology · Statistics 2025-05-19 Yunwen Ji , Mark van der Laan , Alan Hubbard

Item Response Theory (IRT) is a ubiquitous model for understanding human behaviors and attitudes based on their responses to questions. Large modern datasets offer opportunities to capture more nuances in human behavior, potentially…

Machine Learning · Computer Science 2022-07-29 Mike Wu , Richard L. Davis , Benjamin W. Domingue , Chris Piech , Noah Goodman

Implicit Neural representations (INRs) are widely used for scientific data reduction and visualization by modeling the function that maps a spatial location to a data value. Without any prior knowledge about the spatial distribution of…

Graphics · Computer Science 2024-02-22 Haoyu Li , Han-Wei Shen

The drift sequential parameter estimation problems for the Cox-Ingersoll-Ross (CIR) processes under the limited duration of observation are studied. Truncated sequential estimation methods for both scalar and {two}-dimensional parameter…

Statistics Theory · Mathematics 2025-04-08 Mohamed Ben Alaya , Thi-Bao Trâm Ngô , Serguei Pergamenchtchikov
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