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As repositories of large scale data in earth observation (EO) have grown, so have transfer and storage costs for model training and inference, expending significant resources. We introduce Neural Embedding Compression (NEC), based on the…

Machine Learning · Computer Science 2024-07-11 Carlos Gomes , Thomas Brunschwiler

The dynamics of biomolecules are crucial for our understanding of their functioning in living systems. However, current 3D imaging techniques, such as cryogenic electron microscopy (cryo-EM), require freezing the sample, which limits the…

Quantitative Methods · Quantitative Biology 2023-08-24 Enze Ye , Yuhang Wang , Hong Zhang , Yiqin Gao , Huan Wang , He Sun

Automated cell detection and localization from microscopy images are significant tasks in biomedical research and clinical practice. In this paper, we design a new cell detection and localization algorithm that combines deep convolutional…

Computer Vision and Pattern Recognition · Computer Science 2018-10-09 Yao Xue , Gilbert Bigras , Judith Hugh , Nilanjan Ray

We revisit the topic of common lines between projection images in single particle cryo-electron microscopy (cryo-EM). We derive a novel low-rank constraint on a certain $2n \times n$ matrix storing properly-scaled basis vectors for the…

Optimization and Control · Mathematics 2024-06-10 Tommi Muller , Adriana L. Duncan , Eric J. Verbeke , Joe Kileel

Particle picking is a time-consuming step in single-particle analysis and often requires significant interventions from users, which has become a bottleneck for future automated electron cryo-microscopy (cryo-EM). Here we report a deep…

Quantitative Methods · Quantitative Biology 2016-05-09 Feng Wang , Huichao Gong , Gaochao liu , Meijing Li , Chuangye Yan , Tian Xia , Xueming Li , Jianyang Zeng

Particle picking is currently a critical step in the cryo-electron microscopy single particle reconstruction pipeline. Contaminations in the acquired micrographs severely degrade the performance of particle pickers, resulting is many…

Computer Vision and Pattern Recognition · Computer Science 2022-01-19 Amitay Eldar , Ido Amos , Yoel Shkolnisky

Topological Deep Learning seeks to enhance the predictive performance of neural network models by harnessing topological structures in input data. Topological neural networks operate on spaces such as cell complexes and hypergraphs, that…

Machine learning algorithms have been available since the 1990s, but it is much more recently that they have come into use also in the physical sciences. While these algorithms have already proven to be useful in uncovering new properties…

Computational Physics · Physics 2020-05-13 Higor Y. D. Sigaki , Ervin K. Lenzi , Rafael S. Zola , Matjaz Perc , Haroldo V. Ribeiro

Nanoparticles occur in various environments as a consequence of man-made processes, which raises concerns about their impact on the environment and human health. To allow for proper risk assessment, a precise and statistically relevant…

This thesis studies how the segmentation results, produced by convolutional neural networks (CNN), is different from each other when applied to small biomedical datasets. We use different architectures, parameters and hyper-parameters,…

Image and Video Processing · Electrical Eng. & Systems 2020-11-04 Vitaly Nikolaev

An automatic approach to counting any kind of cells could alleviate work of the experts and boost the research in fields such as regenerative medicine. In this paper, a method for microscopy cell counting using multiple frames (hence…

Computer Vision and Pattern Recognition · Computer Science 2018-02-01 Alexander Gomez Villa , Augusto Salazar , Igor Stefanini

In this work, we present a novel background subtraction system that uses a deep Convolutional Neural Network (CNN) to perform the segmentation. With this approach, feature engineering and parameter tuning become unnecessary since the…

Computer Vision and Pattern Recognition · Computer Science 2017-02-07 Mohammadreza Babaee , Duc Tung Dinh , Gerhard Rigoll

Named-entity recognition (NER) aims at identifying entities of interest in a text. Artificial neural networks (ANNs) have recently been shown to outperform existing NER systems. However, ANNs remain challenging to use for non-expert users.…

Computation and Language · Computer Science 2017-05-17 Franck Dernoncourt , Ji Young Lee , Peter Szolovits

Microscopy images from different imaging conditions, organs, and tissues often have numerous cells with various shapes on a range of backgrounds. As a result, designing a deep learning model to count cells in a source domain becomes…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Zuhui Wang

Automatic cell segmentation in microscopy images works well with the support of deep neural networks trained with full supervision. Collecting and annotating images, though, is not a sustainable solution for every new microscopy database…

Computer Vision and Pattern Recognition · Computer Science 2020-07-06 Youssef Dawoud , Julia Hornauer , Gustavo Carneiro , Vasileios Belagiannis

Although deep learning techniques have been successfully applied to many tasks, interpreting deep neural network models is still a big challenge to us. Recently, many works have been done on visualizing and analyzing the mechanism of deep…

Machine Learning · Statistics 2018-06-25 Lin Guo , Hui Ye , Wenbo Su , Henhuan Liu , Kai Sun , Hang Xiang

Operando/in-situ liquid cell transmission electron microscopy (LCTEM) allows for real time imaging of dynamic nanoscale liquid-based processes. However, due to the thick liquid cell of traditional LCTEM holders and thus scattering of the…

Structural flexibility and/or dynamic interactions with other molecules is a critical aspect of protein function. CryoEM provides direct visualization of individual macromolecules sampling different conformational and compositional states.…

Biomolecules · Quantitative Biology 2021-08-04 Muyuan Chen , Steven Ludtke

We study classifiers operating under severe classification time constraints, corresponding to 1-1000 CPU microseconds, using Convolutional Tables Ensemble (CTE), an inherently fast architecture for object category recognition. The…

Computer Vision and Pattern Recognition · Computer Science 2016-02-16 Aharon Bar-Hillel , Eyal Krupka , Noam Bloom

We propose a novel Convolutional Neural Network (CNN) compression algorithm based on coreset representations of filters. We exploit the redundancies extant in the space of CNN weights and neuronal activations (across samples) in order to…

Computer Vision and Pattern Recognition · Computer Science 2018-07-27 Abhimanyu Dubey , Moitreya Chatterjee , Narendra Ahuja
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