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Quantitative susceptibility mapping (QSM) inevitably suffers from streaking artifacts caused by zeros on the conical surface of the dipole kernel in k-space. This work proposes a novel and accurate QSM reconstruction method based on a…

Computer Vision and Pattern Recognition · Computer Science 2019-10-16 Hyun-Seo Ahn , Sung-Hong Park , Jong Chul Ye

It is well-known that reconstruction algorithms in quantitative susceptibility mapping often contain streaking artifacts. In [1], the cause of the artifacts is identified as propagation of singularities. In this work, we analyze such…

Analysis of PDEs · Mathematics 2016-09-26 Benjamin Palacios , Gunther Uhlmann , Yiran Wang

Identifying and suppressing streaking artifacts is one of the most challenging problems in quantitative susceptibility mapping. The measured phase from tissue magnetization is assumed to be the convolution by the magnetic dipole kernel;…

Image and Video Processing · Electrical Eng. & Systems 2025-10-29 Ignacio Contreras-Zúñiga , Mathias Lambert , Benjamín Palacios , Cristian Tejos , Carlos Milovic

Quantitative susceptibility mapping (QSM) aims to visualize the three dimensional susceptibility distribution by solving the field-to-source inverse problem using the phase data in magnetic resonance signal. However, the inverse problem is…

Numerical Analysis · Mathematics 2018-12-31 Chenglong Bao , Jae Kyu Choi , Bin Dong

Purpose: Quantitative Susceptibility Mapping (QSM) reconstruction is a challenging inverse problem driven by poor conditioning of the field to susceptibility transformation. State-of-art QSM reconstruction methods either suffer from image…

Medical Physics · Physics 2019-03-14 Juan Liu , Andrew S. Nencka , L. Tugan Muftuler , Brad Swearingen , Robin Karr , Kevin M. Koch

The starting point in quantitative susceptibility mapping (QSM) is a theoretical model that is used to map susceptibility distributions from magnetic field measurements. It requires regularisation techniques to avoid artefacts in the…

Mathematical Physics · Physics 2021-09-07 Rob F. Remis , Peter M. van den Berg

Quantitative susceptibility mapping (QSM) is a powerful MRI technique that has shown great potential in quantifying tissue susceptibility in numerous neurological disorders. However, the intrinsic ill-posed dipole inversion problem greatly…

Image and Video Processing · Electrical Eng. & Systems 2019-10-31 Yicheng Chen , Angela Jakary , Sivakami Avadiappan , Christopher P. Hess , Janine M. Lupo

Quantitative susceptibility mapping (QSM) utilizes MRI signal phase to infer estimates of local tissue magnetism (magnetic susceptibility), which has been shown useful to provide novel image contrast and as biomarkers of abnormal tissue.…

Medical Physics · Physics 2019-04-16 Juan Liu , Kevin M. Koch

Quantitative Susceptibility Mapping (QSM) dipole inversion is an ill-posed inverse problem for quantifying magnetic susceptibility distributions from MRI tissue phases. While supervised deep learning methods have shown success in specific…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Zhuang Xiong , Wei Jiang , Yang Gao , Feng Liu , Hongfu Sun

Quantitative susceptibility mapping (QSM) is an MRI phase-based post-processing technique to extract the distribution of tissue susceptibilities, demonstrating significant potential in studying neurological diseases. However, the…

Image and Video Processing · Electrical Eng. & Systems 2024-06-19 Min Li , Chen Chen , Zhuang Xiong , Ying Liu , Pengfei Rong , Shanshan Shan , Feng Liu , Hongfu Sun , Yang Gao

Quantitative susceptibility mapping (QSM) is a valuable magnetic resonance imaging (MRI) contrast mechanism that has demonstrated broad clinical applications. However, the image reconstruction of QSM is challenging due to its ill-posed…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Yang Gao , Xuanyu Zhu , Bradford A. Moffat , Rebecca Glarin , Alan H. Wilman , G. Bruce Pike , Stuart Crozier , Feng Liu , Hongfu Sun

Quantitative susceptibility mapping (QSM) utilizes MRI signal phase to estimate local tissue susceptibility, which has been shown useful to provide novel image contrast and as biomarkers of abnormal tissue. QSM requires addressing a…

Medical Physics · Physics 2019-06-03 Juan Liu , Kevin M. Koch

Quantitative susceptibility mapping (QSM) is a magnetic resonance imaging (MRI) technique that estimates magnetic susceptibility of tissue from Larmor frequency offset measurements. The generation of QSM requires solving a challenging…

Medical Physics · Physics 2020-08-18 Juan Liu , Kevin M. Koch

Background: Quantitative susceptibility mapping (QSM) of the brain is an advanced MRI technique for assessing tissue characteristics based on magnetic susceptibility, which varies with the composition of the tissue, such as iron, calcium,…

Quantitative Susceptibility Mapping (QSM) quantifies tissue magnetic susceptibility from magnetic-resonance phase data and plays a crucial role in brain microstructure imaging, iron-deposition assessment, and neurological-disease research.…

Image and Video Processing · Electrical Eng. & Systems 2025-12-11 Xuan Cai , Ruo-Mi Guo , Xiao-Wen Luo , Jing Zhao , Silun Wang , Tao Tan , Yue Liu , Hongbin Han , Mengting Liu

Deep neural networks have demonstrated promising potential for the field of medical image reconstruction. In this work, an MRI reconstruction algorithm, which is referred to as quantitative susceptibility mapping (QSM), has been developed…

Image and Video Processing · Electrical Eng. & Systems 2018-06-18 Jaeyeon Yoon , Enhao Gong , Itthi Chatnuntawech , Berkin Bilgic , Jingu Lee , Woojin Jung , Jingyu Ko , Hosan Jung , Kawin Setsompop , Greg Zaharchuk , Eung Yeop Kim , John Pauly , Jongho Lee

Quantitative susceptibility mapping (QSM) is a useful magnetic resonance imaging (MRI) technique which provides spatial distribution of magnetic susceptibility values of tissues. QSMs can be obtained by deconvolving the dipole kernel from…

Computer Vision and Pattern Recognition · Computer Science 2020-12-08 Gyutaek Oh , Hyokyoung Bae , Hyun-Seo Ahn , Sung-Hong Park , Jong Chul Ye

Quantitative Susceptibility Mapping (QSM) reconstruction is a challenging inverse problem driven by ill conditioning of its field-to -susceptibility transformation. State-of-art QSM reconstruction methods either suffer from image artifacts…

Artificial Intelligence · Computer Science 2019-04-12 Juan Liu , Kevin M. Koch

Introduction: Quantitative Susceptibility Mapping (QSM) is generally acquired with full brain coverage, even though many QSM brain-iron studies focus on the deep grey matter (DGM) region only. Reducing the spatial coverage to the DGM…

Quantitative Methods · Quantitative Biology 2021-06-02 Xuanyu Zhu , Yang Gao , Feng Liu , Stuart Crozier , Hongfu Sun

Purpose: For quantitative susceptibility mapping (QSM), the lack of ground-truth in clinical settings makes it challenging to determine suitable parameters for the dipole inversion. We propose a probabilistic Bayesian approach for QSM with…

Image and Video Processing · Electrical Eng. & Systems 2023-06-01 Shuai Huang , James J. Lah , Jason W. Allen , Deqiang Qiu
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