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We consider the analysis of continuous repeated measurement outcomes that are collected through time, also known as longitudinal data. A standard framework for analysing data of this kind is a linear Gaussian mixed-effects model within…

Methodology · Statistics 2018-04-10 Özgür Asar , David Bolin , Peter J. Diggle , Jonas Wallin

When language models are trained by reinforcement learning (RL) to write probabilistic programs, they can artificially inflate their marginal-likelihood reward by producing programs whose data distribution fails to normalise instead of…

Machine Learning · Computer Science 2026-03-26 Jacek Karwowski , Younesse Kaddar , Zihuiwen Ye , Nikolay Malkin , Sam Staton

The large-sample properties of likelihood-based statistical inference under mixture models have received much attention from statisticians. Although the consistency of the nonparametric MLE is regarded as a standard conclusion, many…

Statistics Theory · Mathematics 2016-07-06 Jiahua Chen

Count outcomes in longitudinal studies are frequent in clinical and engineering studies. In frequentist and Bayesian statistical analysis, methods such as Mixed linear models allow the variability or correlation within individuals to be…

Methodology · Statistics 2024-07-15 Alejandra Estefanía Patiño Hoyos , Johnatan Cardona Jiménez

Mixed modeling of extreme values and random effects is relatively unexplored topic. Computational difficulties in using the maximum likelihood method for mixed models and the fact that maximum likelihood method uses available data and does…

Applications · Statistics 2019-07-05 Ali Reza Fotouhi

Despite remarkable advances in coding capabilities, language models (LMs) still struggle with simple syntactic tasks such as generating balanced parentheses. In this study, we investigate the underlying mechanisms behind the persistence of…

Computation and Language · Computer Science 2025-07-02 Daking Rai , Samuel Miller , Kevin Moran , Ziyu Yao

Theories of consciousness depend on data, and it needs to be appropriate data, without overwhelming confounding factors. The reports of Minimal Phenomenal Experience (MPE) in [Metzinger 2024] relate to consciousness in a state purer than…

Neurons and Cognition · Quantitative Biology 2025-09-30 Robert Worden

We study uniform consistency in nonparametric mixture models as well as closely related mixture of regression (also known as mixed regression) models, where the regression functions are allowed to be nonparametric and the error…

Statistics Theory · Mathematics 2022-12-29 Bryon Aragam , Ruiyi Yang

Estimation of generalized linear mixed models (GLMMs) with non-nested random effects structures requires approximation of high-dimensional integrals. Many existing methods are tailored to the low-dimensional integrals produced by nested…

Computation · Statistics 2014-04-01 Andrew T. Karl , Yan Yang , Sharon L. Lohr

Linear mixed-effects model (LMM) is a cornerstone of longitudinal data analysis, but is limited to adeptly make heterogeneous analyses predictable under both group-specific fixed effects and subject-specific random effects. To address this…

Methodology · Statistics 2026-03-10 Xinkai Yue , Xiaodong Yan , Haohui Han , Liya Fu

The issue of fairness arises when the automatic speech recognition (ASR) systems do not perform equally well for all subgroups of the population. In any fairness measurement studies for ASR, the open questions of how to control the nuisance…

Machine Learning · Statistics 2021-09-21 Zhe Liu , Irina-Elena Veliche , Fuchun Peng

Extracting meaning from uncertain, noisy data is a fundamental problem across time series analysis, pattern recognition, and language modeling. This survey presents a unified mathematical framework that connects classical estimation theory,…

Machine Learning · Computer Science 2025-08-22 Mohammed Elmusrati

With the arrival of the R packages nlme and lme4, linear mixed models (LMMs) have come to be widely used in experimentally-driven areas like psychology, linguistics, and cognitive science. This tutorial provides a practical introduction to…

Methodology · Statistics 2020-01-17 Tanner Sorensen , Shravan Vasishth

The lack of non-parametric statistical tests for confounding bias significantly hampers the development of robust, valid and generalizable predictive models in many fields of research. Here I propose the partial and full confounder tests,…

Machine Learning · Computer Science 2025-05-30 Tamas Spisak

Non-linear mixed effects modeling and simulation (NLME M&S) is evaluated to be used for standardization with longitudinal data in presence of confounders. Standardization is a well-known method in causal inference to correct for confounding…

The convergence of expectation-maximization (EM)-based algorithms typically requires continuity of the likelihood function with respect to all the unknown parameters (optimization variables). The requirement is not met when parameters…

Signal Processing · Electrical Eng. & Systems 2024-04-18 Geethu Joseph

Evaluating alignment in language models requires testing how they behave under realistic pressure, not just what they claim they would do. While alignment failures increasingly cause real-world harm, comprehensive evaluation frameworks with…

Artificial Intelligence · Computer Science 2026-02-25 Nora Petrova , John Burden

In fitting a mixture of linear regression models, normal assumption is traditionally used to model the error and then regression parameters are estimated by the maximum likelihood estimators (MLE). This procedure is not valid if the normal…

Methodology · Statistics 2018-11-06 Yanyuan Ma , Shaoli Wang , Lin Xu , Weixin Yao

This paper builds on recent research that focuses on regression modeling of continuous bounded data, such as proportions measured on a continuous scale. Specifically, it deals with beta regression models with mixed effects from a Bayesian…

Large language models are increasingly deployed to simulate patients for clinical training, research, and mental health tools, yet population-level validity remains largely untested. We introduce PsychBench, the first epidemiological audit…

Computers and Society · Computer Science 2026-04-21 Patrick Keough