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We use mathematical methods from the theory of tailored random graphs to study systematically the effects of sampling on topological features of large biological signalling networks. Our aim in doing so is to increase our quantitative…

Quantitative Methods · Quantitative Biology 2011-06-02 A. Annibale , A. C. C. Coolen

Understanding human mobility is of vital importance for urban planning, epidemiology, and many other fields that aim to draw policies from the activities of humans in space. Despite recent availability of large scale data sets related to…

Physics and Society · Physics 2015-08-18 Oleguer Sagarra , Michael Szell , Paolo Santi , Albert Diaz-Guilera , Carlo Ratti

Empirical researchers often estimate spillover effects by fitting linear or non-linear regression models to sampled network data. We show that common sampling schemes bias these estimates, potentially upwards, and derive biased-corrected…

General Economics · Economics 2025-09-23 Kieran Marray

Cities are some of the most intricate and advanced creations of humanity. Most objects in cities are perfectly synchronised to coordinate activities such as jobs, education, transportation, entertainment, and waste management. Although each…

Physics and Society · Physics 2026-04-01 Rafael Prieto-Curiel

Avalanches of electrochemical activity in brain networks have been empirically reported to obey scale-invariant behavior --characterized by power-law distributions up to some upper cut-off-- both in vitro and in vivo. Elucidating whether…

Neurons and Cognition · Quantitative Biology 2018-01-03 Matteo Martinello , Jorge Hidalgo , Serena di Santo , Amos Maritan , Dietmar Plenz , Miguel A. Muñoz

Diffusion and propagation of information, influence and diseases take place over increasingly larger networks. We observe when a node copies information, makes a decision or becomes infected but networks are often hidden or unobserved.…

Social and Information Networks · Computer Science 2012-05-09 Manuel Gomez Rodriguez , Bernhard Schölkopf

Many fluctuating systems consist of macroscopic structures in addition to noisy signals. Thus, for this class of fluctuating systems, the scaling behaviors are very complicated. Such phenomena are quite commonly observed in Nature, ranging…

Statistical Mechanics · Physics 2007-05-23 Ning-Ning Pang , Hisen-Ching Kao , Wen-Jer Tzeng

We define several new models for how to define anomalous regions among enormous sets of trajectories. These are based on spatial scan statistics, and identify a geometric region which captures a subset of trajectories which are…

Data Structures and Algorithms · Computer Science 2019-06-06 Michael Matheny , Dong Xie , Jeff M. Phillips

Sample complexity of bias estimation is a lower bound on the runtime of any bias detection method. Many regulatory frameworks require the bias to be tested for all subgroups, whose number grows exponentially with the number of protected…

Machine Learning · Computer Science 2025-02-06 German Martinez Matilla , Jakub Marecek

Inferring network topology from smooth signals is a significant problem in data science and engineering. A common challenge in real-world scenarios is the availability of only partially observed nodes. While some studies have considered…

Machine Learning · Computer Science 2025-07-08 Chuansen Peng , Hanning Tang , Zhiguo Wang , Xiaojing Shen

We propose a model of random diffusion to investigate flow fluctuations in complex networks. We derive an analytical law showing that the dependence of fluctuations with the mean traffic in a network is ruled by the delicate interplay of…

Physics and Society · Physics 2008-05-21 S. Meloni , J. Gomez-Gardenes , V. Latora , Y. Moreno

The scaling of correlations as a function of system size provides important hints to understand critical phenomena on a variety of systems. Its study in biological systems offers two challenges: usually they are not of infinite size, and in…

Disordered Systems and Neural Networks · Physics 2020-07-17 Daniel A. Martin , Tiago L. Ribeiro , Sergio A. Cannas , Tomas S. Grigera , Dietmar Plenz , Dante R. Chialvo

Sparse subspace clustering (SSC) is an elegant approach for unsupervised segmentation if the data points of each cluster are located in linear subspaces. This model applies, for instance, in motion segmentation if some restrictions on the…

Machine Learning · Statistics 2018-02-12 Hanno Ackermann , Michael Ying Yang , Bodo Rosenhahn

Subsampling is one of the popular methods to balance statistical efficiency and computational efficiency in the big data era. Most approaches aim at selecting informative or representative sample points to achieve good overall information…

Methodology · Statistics 2024-07-10 Haolin Chen , Holger Dette , Jun Yu

Recent works have proposed optimal subsampling algorithms to improve computational efficiency in large datasets and to design validation studies in the presence of measurement error. Existing approaches generally fall into two categories:…

Methodology · Statistics 2025-12-25 Jasper B. Yang , Thomas Lumley , Bryan E. Shepherd , Pamela A. Shaw

The presence of self-organized criticality in biology is often evidenced by a power-law scaling of event size distributions, which can be measured by linear regression on logarithmic axes. We show here that such a procedure does not…

Adaptation and Self-Organizing Systems · Physics 2015-05-14 Jonathan Touboul , Alain Destexhe

A random network model which allows for tunable, quite general forms of clustering, degree correlation and degree distribution is defined. The model is an extension of the configuration model, in which stubs (half-edges) are paired to form…

Probability · Mathematics 2012-07-31 Frank Ball , Tom Britton , David Sirl

The "critical brain hypothesis" posits that neural circuitry may be tuned close to a "critical point" or "phase transition" -- a boundary between different operating regimes of the circuit. The renormalization group and theory of critical…

Neurons and Cognition · Quantitative Biology 2025-10-30 Braden A. W. Brinkman

Subsampling is an efficient method to deal with massive data. In this paper, we investigate the optimal subsampling for linear quantile regression when the covariates are functions. The asymptotic distribution of the subsampling estimator…

Numerical Analysis · Mathematics 2022-05-06 Qian Yan , Hanyu Li , Chengmei Niu

Neural networks organize information according to the hierarchical, multi-scale structure of natural data. Methods to interpret model internals should be similarly scale-aware, explicitly tracking how features compose across resolutions and…