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Identification and quantification of condition-specific transcripts using RNA-Seq is vital in transcriptomics research. While initial efforts using mathematical or statistical modeling of read counts or per-base exonic signal have been…

Quantitative Methods · Quantitative Biology 2013-02-26 Tin Chi Nguyen , Nan Deng , Dongxiao Zhu

Dysfluent speech modeling requires time-accurate and silence-aware transcription at both the word-level and phonetic-level. However, current research in dysfluency modeling primarily focuses on either transcription or detection, and the…

Audio and Speech Processing · Electrical Eng. & Systems 2023-12-21 Jiachen Lian , Carly Feng , Naasir Farooqi , Steve Li , Anshul Kashyap , Cheol Jun Cho , Peter Wu , Robbie Netzorg , Tingle Li , Gopala Krishna Anumanchipalli

Diffusion models have recently driven significant breakthroughs in generative modeling. While state-of-the-art models produce high-quality samples on average, individual samples can still be low quality. Detecting such samples without human…

Machine Learning · Computer Science 2025-06-13 Metod Jazbec , Eliot Wong-Toi , Guoxuan Xia , Dan Zhang , Eric Nalisnick , Stephan Mandt

Single-Cell RNA sequencing (scRNA-seq) measurements have facilitated genome-scale transcriptomic profiling of individual cells, with the hope of deconvolving cellular dynamic changes in corresponding cell sub-populations to better…

Genomics · Quantitative Biology 2021-04-06 Seyednami Niyakan , Ehsan Hajiramezanali , Shahin Boluki , Siamak Zamani Dadaneh , Xiaoning Qian

We propose a variational Bayesian (VB) approach to learning distributions of latent variables in deep neural network (DNN) models for cross-domain knowledge transfer, to address acoustic mismatches between training and testing conditions.…

Audio and Speech Processing · Electrical Eng. & Systems 2022-02-22 Hu Hu , Sabato Marco Siniscalchi , Chao-Han Huck Yang , Chin-Hui Lee

We introduce a model of DNA sequence evolution which can account for biases in mutation rates that depend on the identity of the neighboring bases. An analytic solution for this class of non-equilibrium models is developed by adopting…

Biological Physics · Physics 2007-05-23 Peter F. Arndt , Christopher B. Burge , Terence Hwa

Remote sensing change detection is crucial for understanding the dynamics of our planet's surface, facilitating the monitoring of environmental changes, evaluating human impact, predicting future trends, and supporting decision-making. In…

Computer Vision and Pattern Recognition · Computer Science 2024-01-15 Wele Gedara Chaminda Bandara , Nithin Gopalakrishnan Nair , Vishal M. Patel

Recent evidence suggests that analyzing the presence/absence of taxonomic features can offer a compelling alternative to differential abundance analysis in microbiome studies. However, standard approaches to differential prevalence analysis…

Methodology · Statistics 2026-05-26 Juho Pelto , Kari Auranen , Janne V. Kujala , Leo Lahti

Generally, the performance of deep neural networks (DNNs) heavily depends on the quality of data representation learning. Our preliminary work has emphasized the significance of deep representation learning (DRL) in the context of speech…

Audio and Speech Processing · Electrical Eng. & Systems 2023-12-18 Yang Xiang , Jingguang Tian , Xinhui Hu , Xinkang Xu , ZhaoHui Yin

We present a technique to characterize differentially expressed genes in terms of their position in a high-dimensional co-expression network. The set-up of Gaussian graphical models is used to construct representations of the co-expression…

Applications · Statistics 2010-11-17 Gabriel C. G. de Abreu , Rodrigo Labouriau

Isoform quantification is an important goal of RNA-seq experiments, yet it remains prob- lematic for genes with low expression or several isoforms. These difficulties may in principle be ameliorated by exploiting correlated experimental…

Genomics · Quantitative Biology 2016-02-23 Yuanhua Huang , Guido Sanguinetti

A prominent family of methods for learning data distributions relies on density ratio estimation (DRE), where a model is trained to $\textit{classify}$ between data samples and samples from some reference distribution. DRE-based models can…

Machine Learning · Computer Science 2024-11-01 Shahar Yadin , Noam Elata , Tomer Michaeli

The ever-increasing demand for broadband Internet access has motivated the further development of the digital subscriber line to the G.fast standard in order to expand its operational band from 106 MHz to 212 MHz. Conventional far-end…

Information Theory · Computer Science 2018-06-18 Jiankang Zhang , Sheng Chen , Rong Zhang , Anas F. Al Rawi , Lajos Hanzo

Causal inference using observational text data is becoming increasingly popular in many research areas. This paper presents the Bayesian Topic Regression (BTR) model that uses both text and numerical information to model an outcome…

Machine Learning · Statistics 2021-09-14 Maximilian Ahrens , Julian Ashwin , Jan-Peter Calliess , Vu Nguyen

The explosion in high-resolution data capture technologies in health has increased interest in making inferences about individual-level parameters. While technology may provide substantial data on a single individual, how best to use…

Methodology · Statistics 2021-12-16 Ziyu Ji , Julian Wolfson

Existing tag signal detection algorithms inevitably suffer from a high bit error rate (BER) due to the difficulties in estimating the channel state information (CSI). To eliminate the requirement of channel estimation and to improve the…

Signal Processing · Electrical Eng. & Systems 2020-11-12 Chang Liu , Xuemeng Liu , Zhiqiang Wei , Derrick Wing Kwan Ng , Jinhong Yuan , Ying-Chang Liang

In this paper, we consider a dynamic radio frequency sensing system aiming to spatially track multiple targets over time. We develop a conditional denoising diffusion probabilistic model (C-DDPM)-assisted framework that learns the temporal…

Signal Processing · Electrical Eng. & Systems 2025-10-30 Amirhossein Azarbahram , Onel L. A. López

Differential privacy guarantees allow the results of a statistical analysis involving sensitive data to be released without compromising the privacy of any individual taking part. Achieving such guarantees generally requires the injection…

Machine Learning · Statistics 2023-10-31 Jack Jewson , Sahra Ghalebikesabi , Chris Holmes

Efficient new Bayesian inference technique is employed for studying critical properties of the Ising linear perceptron and for signal detection in Code Division Multiple Access (CDMA). The approach is based on a recently introduced message…

Disordered Systems and Neural Networks · Physics 2009-11-11 Juan P. Neirotti , David Saad

Dynamic Bayesian networks (DBNs) offer an elegant way to integrate various aspects of language in one model. Many existing algorithms developed for learning and inference in DBNs are applicable to probabilistic language modeling. To…

Computation and Language · Computer Science 2007-05-23 Leonid Peshkin , Avi Pfeffer
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