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Discovery of sensitive and biologically grounded biomarkers is essential for early detection and monitoring of Alzheimer's disease (AD). Structural MRI is widely available but typically relies on hand-crafted features such as cortical…

Multimodal data analysis can lead to more accurate diagnoses of brain disorders due to the complementary information that each modality adds. However, a major challenge of using multimodal datasets in the neuroimaging field is incomplete…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Reihaneh Hassanzadeh , Anees Abrol , Hamid Reza Hassanzadeh , Vince D. Calhoun

In high-contrast imaging, a novel detection algorithm for angular differential imaging (ADI) sequences has recently been introduced: the Regime Switching Model (RSM). In this study, we apply the RSM algorithm to analyze the F150 sample from…

Instrumentation and Methods for Astrophysics · Physics 2026-02-18 Mariam Sabalbal , Olivier Absil , Carl-Henrik Dahlqvist , Philippe Delorme

Despite progress in deep learning for Alzheimer's disease (AD) diagnostics, models trained on structural magnetic resonance imaging (sMRI) often do not perform well when applied to new cohorts due to domain shifts from varying scanners,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Zobia Batool , Diala Lteif , Vijaya B. Kolachalama , Huseyin Ozkan , Erchan Aptoula

Structured illumination microscopy (SIM) has become an important technique for optical super-resolution imaging because it allows a doubling of image resolution at speeds compatible for live-cell imaging. However, the reconstruction of SIM…

Image and Video Processing · Electrical Eng. & Systems 2020-03-26 Charles N. Christensen , Edward N. Ward , Pietro Lio , Clemens F. Kaminski

Most existing text-to-image person retrieval methods usually assume that the training image-text pairs are perfectly aligned; however, the noisy correspondence(NC) issue (i.e., incorrect or unreliable alignment) exists due to poor image…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Runqing Zhang , Xue Zhou

Recent evidence has shown that structural magnetic resonance imaging (MRI) is an effective tool for Alzheimer's disease (AD) prediction and diagnosis. While traditional MRI-based diagnosis uses images acquired at a single time point, a…

Applications · Statistics 2021-11-02 Xiaowu Dai

Recent advances in unsupervised learning have highlighted the possibility of learning to reconstruct signals from noisy and incomplete linear measurements alone. These methods play a key role in medical and scientific imaging and sensing,…

Signal Processing · Electrical Eng. & Systems 2024-10-22 Julián Tachella , Laurent Jacques

Alzheimer's disease (AD) is an irreversible brain disease that can dramatically reduce quality of life, most commonly manifesting in older adults and eventually leading to the need for full-time care. Early detection is fundamental to…

Computation and Language · Computer Science 2019-06-14 Flavio Di Palo , Natalie Parde

Objective: Acquiring fully sampled training data is challenging for many MRI applications. We present a self-supervised image reconstruction method, termed ReSiDe, capable of recovering images solely from undersampled data. Materials and…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Muhammad Shafique , Sizhuo Liu , Philip Schniter , Rizwan Ahmad

This study investigates the relationship between deep learning (DL) image reconstruction quality and anomaly detection performance, and evaluates the efficacy of an artificial intelligence (AI) assistant in enhancing radiologists'…

A fundamental problem of causal discovery is cause-effect inference, learning the correct causal direction between two random variables. Significant progress has been made through modelling the effect as a function of its cause and a noise…

Machine Learning · Computer Science 2023-10-27 Xiangyu Sun , Oliver Schulte

Quantitative susceptibility mapping (QSM) estimates the underlying tissue magnetic susceptibility from MRI gradient-echo phase signal and typically requires several processing steps. These steps involve phase unwrapping, brain volume…

Image and Video Processing · Electrical Eng. & Systems 2019-05-16 Hongjiang Wei , Steven Cao , Yuyao Zhang , Xiaojun Guan , Fuhua Yan , Kristen W. Yeom , Chunlei Liu

Hand-crafted image quality metrics, such as PSNR and SSIM, are commonly used to evaluate model privacy risk under reconstruction attacks. Under these metrics, reconstructed images that are determined to resemble the original one generally…

Computer Vision and Pattern Recognition · Computer Science 2023-10-10 Xiaoxiao Sun , Nidham Gazagnadou , Vivek Sharma , Lingjuan Lyu , Hongdong Li , Liang Zheng

Objective: This paper presents an Alzheimer's disease (AD) detection method based on learning structural similarity between Magnetic Resonance Images (MRIs) and representing this similarity as a graph. Methods: We construct the similarity…

Computer Vision and Pattern Recognition · Computer Science 2021-03-01 Kuo Yang , Emad A. Mohammed , Behrouz H. Far

High resolution images can be acquired using a non-regular sampling sensor which consists of an underlying low resolution sensor that is covered with a non-regular sampling mask. The reconstructed high resolution image is then obtained…

Image and Video Processing · Electrical Eng. & Systems 2022-04-08 Markus Jonscher , Karina Jaskolka , Jürgen Seiler , André Kaup

Classical scalar-response regression methods treat covariates as a vector and estimate a corresponding vector of regression coefficients. In medical applications, however, regressors are often in a form of multi-dimensional arrays. For…

Methodology · Statistics 2020-02-03 Damian Brzyski , Xixi Hu , Joaquin Goni , Beau Ances , Timothy W. Randolph , Jaroslaw Harezlak

Quantitative susceptibility mapping (QSM) has been increasingly applied in longitudinal studies of neurodegenerative diseases and aging to assess temporal alterations in brain iron and myelin. The accuracy of such investigations depends on…

Quantitative Methods · Quantitative Biology 2026-05-05 Jiye Kim , Hwihun Jeong , Taechang Kim , Eunseon Jeong , Jinhee Jang , Yangsean Choi , Jongho Lee

Causal inference in multivariate time series is challenging due to the fact that the sampling rate may not be as fast as the timescale of the causal interactions. In this context, we can view our observed series as a subsampled version of…

Methodology · Statistics 2017-04-11 Alex Tank , Emily B. Fox , Ali Shojaie

Early detection is a crucial goal in the study of Alzheimer's Disease (AD). In this work, we describe several techniques to boost the performance of 3D deep convolutional neural networks (CNNs) trained to detect AD using structural brain…

Image and Video Processing · Electrical Eng. & Systems 2020-04-07 Sheng Liu , Chhavi Yadav , Carlos Fernandez-Granda , Narges Razavian