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Tumorigenic transformation of human epithelial cells in vitro has been described experimentally as the potential result of a process known as spontaneous immortalization. In this process a generic series of cell state transitions occur in…

Traditional dynamic security assessment faces challenges as power systems are experiencing a transformation to inverter-based-resource (IBR) dominated systems, for which electromagnetic transient (EMT) dynamics have to be considered.…

Dynamical Systems · Mathematics 2023-02-21 Kaiyang Huang , Min Xiong , Yang Liu , Kai Sun , Feng Qiu

Current methods for capturing circulating tumor cells (CTCs) are based on the overexpression of cytokeratin (CK) or epithelial cell-adhesion molecule (EpCAM) on cancer cells. However, during the process of metastasis, tumor cells undergo…

As wounds heal, embryos develop, cancer spreads, or asthma progresses, the cellular monolayer undergoes glass transition between solid-like jammed and fluid-like flowing states. During some of these processes, the cells undergo an…

The brain is intrinsically organized into large-scale networks that constantly re-organize on multiple timescales, even when the brain is at rest. The timing of these dynamics is crucial for sensation, perception, cognition and ultimately…

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Collective cell migration plays an essential role in vertebrate development, yet the extent to which dynamically changing microenvironments influence this phenomenon remains unclear. Observations of the distribution of the extracellular…

A rising interest in the modality extension of foundation language models warrants discussion on the most effective, and efficient, multimodal training approach. This work focuses on neural machine translation (NMT) and proposes a joint…

Cell shape is linked to cell function. The significance of cell morphodynamics, namely the temporal fluctuation of cell shape, is much less understood. Here we study the morphodynamics of MDA-MB-231 cells in type I collagen extracellular…

Cell Behavior · Quantitative Biology 2021-10-12 Christopher Z. Eddy , Helena Raposo , Ryan Wong , Bo Sun

Thermal Energy Storage (TES) devices, which leverage the constant-temperature thermal capacity of the latent heat of a Phase Change Material (PCM), provide benefits to a variety of thermal management systems by decoupling the absorption and…

Systems and Control · Electrical Eng. & Systems 2024-03-01 Trent J. Sakakini , Justin P. Koeln

The shifted frequency-based electromagnetic transient (SFEMT) simulation has greatly improved the computational efficiency of traditional electromagnetic transient (EMT) simulation for the ac grid. This letter proposes a novel interface for…

Systems and Control · Electrical Eng. & Systems 2024-08-28 Shilin Gao , Ying Chen , Zhitong Yu , Wensheng Chen , Yankan Song

Cellular decision making allows cells to assume functionally different phenotypes in response to microenvironmental cues, without genetic change. It is an open question, how individual cell decisions influence the dynamics at the tissue…

Molecular systems can exhibit a complex, chemically tailorable inner structure which allows for targeting of specific mechanical, electronic and optical properties. At the single-molecule level, two major complementary ways to explore these…

Mesoscale and Nanoscale Physics · Physics 2017-04-05 Rocco Gaudenzi , Maciej Misiorny , Enrique Burzurí , Maarten R. Wegewijs , Herre S. J. van der Zant

The impact of repetitive transcranial magnetic stimulation (rTMS) on methamphetamine (METH) users' craving levels is often assessed using questionnaires. This study explores the feasibility of using neural signals to obtain more objective…

Neurons and Cognition · Quantitative Biology 2025-09-29 Ziyi Zeng , Yun-Hsuan Chen , Xurong Gao , Wenyao Zheng , Hemmings Wu , Zhoule Zhu , Jie Yang , Chengkai Wang , Lihua Zhong , Weiwei Cheng , Mohamad Sawan

Semi-supervised segmentation presents a promising approach for large-scale medical image analysis, effectively reducing annotation burdens while achieving comparable performance. This methodology holds substantial potential for streamlining…

Computer Vision and Pattern Recognition · Computer Science 2024-04-11 Zhenxi Zhang , Heng Zhou , Xiaoran Shi , Ran Ran , Chunna Tian , Feng Zhou

Microtubules (MTs) are dynamic protein filaments essential for intracellular organization and transport, particularly in long-lived cells such as neurons. The plus and minus ends of neuronal MTs switch between growth and shrinking phases,…

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We discuss a theoretical description of the inelastic electron tunneling spectra (IETS) of a magnetic nanosystem (an atom or a molecule) adsorbed on a solid surface measured in a scanning tunneling microscope (STM). We represent the…

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The extracellular matrix (ECM) is a highly complex structure through which biochemical and mechanical signals are transmitted. In processes of cell migration, the ECM also acts as a scaffold, providing structural support to cells as well as…

Corneal endothelial cell segmentation plays a vital role inquantifying clinical indicators such as cell density, coefficient of variation,and hexagonality. However, the corneal endothelium's uneven reflectionand the subject's tremor and…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Yinglin Zhang , Risa Higashita , Huazhu Fu , Yanwu Xu , Yang Zhang , Haofeng Liu , Jian Zhang , Jiang Liu

Cell adhesion and migration are strongly influenced by extracellular matrix (ECM) architecture and rigidity, but little is known about the concomitant influence of such environmental signals to cell responses, especially when considering…

Cross-modality magnetic resonance (MR) image synthesis can be used to generate missing modalities from given ones. Existing (supervised learning) methods often require a large number of paired multi-modal data to train an effective…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Yonghao Li , Tao Zhou , Kelei He , Yi Zhou , Dinggang Shen