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Multiple Sequence Alignment (MSA) is one of the most computationally intensive tasks in Computational Biology. Existing best known solutions for multiple sequence alignment take several hours (in some cases days) of computation time to…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-01-20 Fahad Saeed , Ashfaq Khokhar

Multiple Sequences Alignment (MSA) of biological sequences is a fundamental problem in computational biology due to its critical significance in wide ranging applications including haplotype reconstruction, sequence homology, phylogenetic…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-05-13 Fahad Saeed , Ashfaq Khokhar

We consider a setting in which $N$ agents aim to speedup a common Stochastic Approximation (SA) problem by acting in parallel and communicating with a central server. We assume that the up-link transmissions to the server are subject to…

Artificial Intelligence · Computer Science 2024-08-05 Nicolò Dal Fabbro , Arman Adibi , H. Vincent Poor , Sanjeev R. Kulkarni , Aritra Mitra , George J. Pappas

High-dimensional data requires scalable algorithms. We propose and analyze three scalable and related algorithms for semi-supervised discriminant analysis (SDA). These methods are based on Krylov subspace methods which exploit the data…

Artificial Intelligence · Computer Science 2019-02-21 Joris Tavernier , Jaak Simm , Karl Meerbergen , Joerg Kurt Wegner , Hugo Ceulemans , Yves Moreau

This paper considers convex optimization problems where nodes of a network have access to summands of a global objective. Each of these local objectives is further assumed to be an average of a finite set of functions. The motivation for…

Optimization and Control · Mathematics 2015-06-16 Aryan Mokhtari , Alejandro Ribeiro

Recent advances in Deep Neural Networks (DNNs) have led to active development of specialized DNN accelerators, many of which feature a large number of processing elements laid out spatially, together with a multi-level memory hierarchy and…

Machine Learning · Computer Science 2021-05-06 Qijing Huang , Minwoo Kang , Grace Dinh , Thomas Norell , Aravind Kalaiah , James Demmel , John Wawrzynek , Yakun Sophia Shao

Transformers are the mainstream of NLP applications and are becoming increasingly popular in other domains such as Computer Vision. Despite the improvements in model quality, the enormous computation costs make Transformers difficult at…

Machine Learning · Computer Science 2021-10-22 Liu Liu , Zheng Qu , Zhaodong Chen , Yufei Ding , Yuan Xie

Sequence alignment supports numerous tasks in bioinformatics, natural language processing, pattern recognition, social sciences, and others fields. While the alignment of two sequences may be performed swiftly in many applications, the…

Data Structures and Algorithms · Computer Science 2021-12-06 Eloi Araujo , Luiz Rozante , Diego P. Rubert , Fabio V. Martinez

Present day machine learning is computationally intensive and processes large amounts of data. It is implemented in a distributed fashion in order to address these scalability issues. The work is parallelized across a number of computing…

Machine Learning · Computer Science 2017-03-28 Alexander Ulanov , Andrey Simanovsky , Manish Marwah

Current trends in scientific imaging are challenged by the emerging need of integrating sophisticated machine learning with Big Data analytics platforms. This work proposes an in-memory distributed learning architecture for enabling…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-10-01 A. Panousopoulou , S. Farrens , K. Fotiadou , A. Woiselle , G. Tsagkatakis , J-L. Starck , P. Tsakalides

Time Series Alignment is a critical task in signal processing with numerous real-world applications. In practice, signals often exhibit temporal shifts and scaling, making classification on raw data prone to errors. This paper introduces a…

Machine Learning · Computer Science 2025-02-27 Alireza Nourbakhsh , Hoda Mohammadzade

As semiconductor power density is no longer constant with the technology process scaling down, modern CPUs are integrating capable data accelerators on chip, aiming to improve performance and efficiency for a wide range of applications and…

Hardware Architecture · Computer Science 2024-01-31 Reese Kuper , Ipoom Jeong , Yifan Yuan , Jiayu Hu , Ren Wang , Narayan Ranganathan , Nam Sung Kim

Multiple sequence alignment (MSA) has been one of the most important problems in bioinformatics for more decades and it is still heavily examined by many mathematicians and biologists. However, mostly because of the practical motivation of…

Quantitative Methods · Quantitative Biology 2015-11-17 Kristóf Takács

Motivation: The multiple sequence alignment (MSA) problem has been extensively studied, with numerous approaches developed over recent years. With the rapid growth of sequence data, there is an increasing need for fast and accurate MSA…

Computational Engineering, Finance, and Science · Computer Science 2026-01-23 Emily G. Light , Morgan Prior , Noah M. Daniels , Najib Ishaq

We proposed a probabilistic algorithm to solve the Multiple Sequence Alignment problem. The algorithm is a Simulated Annealing (SA) that exploits the representation of the Multiple Alignment between $D$ sequences as a directed polymer in…

Genomics · Quantitative Biology 2016-08-16 M. Hernández-Guía , R. Mulet , S. Rodríguez-Pérez

Many machine learning models, such as logistic regression~(LR) and support vector machine~(SVM), can be formulated as composite optimization problems. Recently, many distributed stochastic optimization~(DSO) methods have been proposed to…

Machine Learning · Statistics 2016-12-13 Shen-Yi Zhao , Ru Xiang , Ying-Hao Shi , Peng Gao , Wu-Jun Li

Deep learning is a popular machine learning technique and has been applied to many real-world problems. However, training a deep neural network is very time-consuming, especially on big data. It has become difficult for a single machine to…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-09-04 Xing Zhao , Aijun An , Junfeng Liu , Bao Xin Chen

The research interest in specialized hardware accelerators for deep neural networks (DNN) spikes recently owing to their superior performance and efficiency. However, today's DNN accelerators primarily focus on accelerating specific…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-06-11 Cong Guo , Yangjie Zhou , Jingwen Leng , Yuhao Zhu , Zidong Du , Quan Chen , Chao Li , Bin Yao , Minyi Guo

Evolutionary modeling applications are the best way to provide full information to support in-depth understanding of evaluation of organisms. These applications mainly depend on identifying the evolutionary history of existing organisms and…

Computational Engineering, Finance, and Science · Computer Science 2018-06-01 Sara Shehab , Sameh Abdulah , Arabi E. Keshk

In prior works, stochastic dual coordinate ascent (SDCA) has been parallelized in a multi-core environment where the cores communicate through shared memory, or in a multi-processor distributed memory environment where the processors…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-11-03 Soumitra Pal , Tingyang Xu , Tianbao Yang , Sanguthevar Rajasekaran , Jinbo Bi
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