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Biomarker discovery from high-throughput transcriptomic data is crucial for advancing precision medicine. However, existing methods often neglect gene-gene regulatory relationships and lack stability across datasets, leading to conflation…

Quantitative Methods · Quantitative Biology 2025-11-18 Chaowang Lan , Jingxin Wu , Yulong Yuan , Chuxun Liu , Huangyi Kang , Caihua Liu

Climate models are essential to understand and project climate change, yet long-standing biases and uncertainties in their projections remain. This is largely associated with the representation of subgrid-scale processes, particularly…

The standard approach to providing interpretability to deep convolutional neural networks (CNNs) consists of visualizing either their feature maps, or the image regions that contribute the most to the prediction. In this paper, we introduce…

Computer Vision and Pattern Recognition · Computer Science 2019-01-09 Krishna Kanth Nakka , Mathieu Salzmann

Traditional machine learning algorithms using hand-crafted feature extraction techniques (such as local binary pattern) have limited accuracy because of high variation in images of the same class (or intra-class variation) for food…

Computer Vision and Pattern Recognition · Computer Science 2018-12-27 Bappaditya Mandal , N. B. Puhan , Avijit Verma

We study optimal covariate balance for causal inferences from observational data when rich covariates and complex relationships necessitate flexible modeling with neural networks. Standard approaches such as propensity weighting and…

Machine Learning · Statistics 2018-02-16 Nathan Kallus

This study investigates the behavior of Causal Convolutional Neural Networks (CNNs) with quasi-linear activation functions when applied to time-series data characterized by multimodal frequency content. We demonstrate that, once trained,…

Machine Learning · Computer Science 2025-10-29 Kiran Bacsa , Wei Liu , Xudong Jian , Huangbin Liang , Eleni Chatzi

We study the problem of graph structure identification, i.e., of recovering the graph of dependencies among time series. We model these time series data as components of the state of linear stochastic networked dynamical systems. We assume…

Machine Learning · Computer Science 2023-06-29 Sérgio Machado , Anirudh Sridhar , Paulo Gil , Jorge Henriques , José M. F. Moura , Augusto Santos

In many practical applications, deep neural networks have been typically deployed to operate as a black box predictor. Despite the high amount of work on interpretability and high demand on the reliability of these systems, they typically…

Artificial Intelligence · Computer Science 2020-12-07 Martin Stano , Wanda Benesova , Lukas Samuel Martak

Despite their success and widespread adoption, the opaque nature of deep neural networks (DNNs) continues to hinder trust, especially in critical applications. Current interpretability solutions often yield inconsistent or oversimplified…

Machine Learning · Computer Science 2024-10-10 Alec F. Diallo , Vaishak Belle , Paul Patras

Causal modeling has been recognized as a potential solution to many challenging problems in machine learning (ML). Here, we describe how a recently proposed counterfactual approach developed to deconfound linear structural causal models can…

Machine Learning · Computer Science 2020-11-23 Elias Chaibub Neto

When engaging in end-to-end graph representation learning with Graph Neural Networks (GNNs), the intricate causal relationships and rules inherent in graph data pose a formidable challenge for the model in accurately capturing authentic…

Machine Learning · Computer Science 2024-06-14 Hang Gao , Peng Qiao , Yifan Jin , Fengge Wu , Jiangmeng Li , Changwen Zheng

Early diagnosis of interstitial lung diseases is crucial for their treatment, but even experienced physicians find it difficult, as their clinical manifestations are similar. In order to assist with the diagnosis, computer-aided diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2016-12-13 Stergios Christodoulidis , Marios Anthimopoulos , Lukas Ebner , Andreas Christe , Stavroula Mougiakakou

We propose a novel approach for inferring the individualized causal effects of a treatment (intervention) from observational data. Our approach conceptualizes causal inference as a multitask learning problem; we model a subject's potential…

Machine Learning · Computer Science 2017-06-20 Ahmed M. Alaa , Michael Weisz , Mihaela van der Schaar

This review systematizes the emerging literature for causal inference using deep neural networks under the potential outcomes framework. It provides an intuitive introduction on how deep learning can be used to estimate/predict…

Machine Learning · Computer Science 2023-11-30 Bernard Koch , Tim Sainburg , Pablo Geraldo , Song Jiang , Yizhou Sun , Jacob Gates Foster

In this paper, we describe a novel deep convolutional neural network (CNN) that is deeper and wider than other existing deep networks for hyperspectral image classification. Unlike current state-of-the-art approaches in CNN-based…

Computer Vision and Pattern Recognition · Computer Science 2017-10-11 Hyungtae Lee , Heesung Kwon

Causal opacity denotes the difficulty in understanding the "hidden" causal structure underlying the decisions of deep neural network (DNN) models. This leads to the inability to rely on and verify state-of-the-art DNN-based systems,…

Recent work has shown promising results in causal discovery by leveraging interventional data with gradient-based methods, even when the intervened variables are unknown. However, previous work assumes that the correspondence between…

Machine Learning · Computer Science 2022-07-12 Gonçalo R. A. Faria , André F. T. Martins , Mário A. T. Figueiredo

As network data applications continue to expand, causal inference within networks has garnered increasing attention. However, hidden confounders complicate the estimation of causal effects. Most methods rely on the strong ignorability…

Machine Learning · Computer Science 2024-09-16 Xiaojing Du , Feiyu Yang , Wentao Gao , Xiongren Chen

Detecting extreme events in large datasets is a major challenge in climate science research. Current algorithms for extreme event detection are build upon human expertise in defining events based on subjective thresholds of relevant…

Computer Vision and Pattern Recognition · Computer Science 2016-05-05 Yunjie Liu , Evan Racah , Prabhat , Joaquin Correa , Amir Khosrowshahi , David Lavers , Kenneth Kunkel , Michael Wehner , William Collins

We introduce a framework for learning robust visual representations that generalize to new viewpoints, backgrounds, and scene contexts. Discriminative models often learn naturally occurring spurious correlations, which cause them to fail on…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Chengzhi Mao , Augustine Cha , Amogh Gupta , Hao Wang , Junfeng Yang , Carl Vondrick