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Metastable brain dynamics are characterized by abrupt, jump-like modulations so that the neural activity in single trials appears to unfold as a sequence of discrete, quasi-stationary states. Evidence that cortical neural activity unfolds…

Neurons and Cognition · Quantitative Biology 2019-06-20 Giancarlo La Camera , Alfredo Fontanini , Luca Mazzucato

Finding the conditions that foster synchronization in networked oscillatory systems is critical to understanding a wide range of biological and mechanical systems. However, the conditions proved in the literature for synchronization in…

Systems and Control · Computer Science 2018-05-09 Zahra Aminzare , Biswadip Dey , Elizabeth N. Davison , Naomi Ehrich Leonard

Thanks to novel, powerful brain activity recording techniques, we can create data-driven models from thousands of recording channels and large portions of the cortex, which can improve our understanding of brain-states neuromodulation and…

We propose a multi-phase approach to explore network structures. In this method, structure analysis is not carried out on the observed network directly. Instead, certain similarity measures of the nodes are derived from the network firstly,…

Physics and Society · Physics 2009-07-03 Xiaofeng Gong , Shuguang Guan , C. -H. Lai

The extensive development of the field of spiking neural networks has led to many areas of research that have a direct impact on people's lives. As the most bio-similar of all neural networks, spiking neural networks not only allow the…

Neural and Evolutionary Computing · Computer Science 2025-07-04 Andrey E. Schegolev , Marina V. Bastrakova , Michael A. Sergeev , Anastasia A. Maksimovskaya , Nikolay V. Klenov , Igor I. Soloviev

Deep learning has recently led to great successes in tasks such as image recognition (e.g Krizhevsky et al., 2012). However, deep networks are still outmatched by the power and versatility of the brain, perhaps in part due to the richer…

Machine Learning · Statistics 2014-03-25 David P. Reichert , Thomas Serre

Synchronization is studied in a spatially-distributed network of weekly-coupled, excitatory neurons of Hodgkin-Huxley type. All neurons are coupled to each other synaptically with a fixed time delay and a coupling strength inversely…

Soft Condensed Matter · Physics 2007-05-23 Yuqing Wang , Z. D. Wang , Y. -X. Li , X. Pei

Identifying the spatio-temporal network structure of brain activity from multi-neuronal data streams is one of the biggest challenges in neuroscience. Repeating patterns of precisely timed activity across a group of neurons is potentially…

Neurons and Cognition · Quantitative Biology 2009-03-03 Casey Diekman , Kohinoor Dasgupta , Vijay Nair , P. S. Sastry , K. P. Unnikrishnan

The success of deep learning in high-dimensional settings is often attributed to the presence of low-dimensional structure in real-world data. While standard theoretical models typically assume that this structure lies in the target…

Machine Learning · Computer Science 2026-05-15 Elisabetta Cornacchia , Laurent Massoulié

We address the problem of finding patterns from multi-neuronal spike trains that give us insights into the multi-neuronal codes used in the brain and help us design better brain computer interfaces. We focus on the synchronous firings of…

Neural and Evolutionary Computing · Computer Science 2010-06-09 Raajay Viswanathan , P. S. Sastry , K. P. Unnikrishnan

Biological and social systems consist of myriad interacting units. The interactions can be represented in the form of a graph or network. Measurements of these graphs can reveal the underlying structure of these interactions, which provides…

Machine Learning · Statistics 2017-10-25 Norbert Binkiewicz , Joshua T. Vogelstein , Karl Rohe

Functional magnetic resonance imaging (fMRI) produces data about activity inside the brain, from which spatial maps can be extracted by independent component analysis (ICA). In datasets, there are n spatial maps that contain p voxels. The…

Computational Engineering, Finance, and Science · Computer Science 2016-11-17 Tuomo Sipola , Fengyu Cong , Tapani Ristaniemi , Vinoo Alluri , Petri Toiviainen , Elvira Brattico , Asoke K. Nandi

Neural circuits exhibit remarkable computational flexibility, enabling adaptive responses to noisy and ever-changing environmental cues. A fundamental question in neuroscience concerns how a wide range of behaviors can emerge from a…

Statistical Mechanics · Physics 2025-09-18 Giacomo Barzon , Daniel M. Busiello , Giorgio Nicoletti

We propose an automatable data-driven methodology for robust nonlinear reduced-order modelling from time-resolved snapshot data. In the kinematical coarse-graining, the snapshots are clustered into few centroids representable for the whole…

Fluid Dynamics · Physics 2020-12-02 Hao Li , Daniel Fernex , Richard Semaan , Jianguo Tan , Marek Morzyński , Bernd R. Noack

Neuronal firing activities have attracted a lot of attention since a large population of spatiotemporal patterns in the brain is the basis for adaptive behavior and can also reveal the signs for various neurological disorders including…

Neurons and Cognition · Quantitative Biology 2017-03-13 Wenyuan Li , Igor V. Ovchinnikov , Honglin Chen , Zhe Wang , Albert Lee , Hochul Lee , Carlos Cepeda , Robert N. Schwartz , Karlheinz Meier , Kang L. Wang

The problem of complex data analysis is a central topic of modern statistical science and learning systems and is becoming of broader interest with the increasing prevalence of high-dimensional data. The challenge is to develop statistical…

Machine Learning · Statistics 2018-03-05 Faicel Chamroukhi , Hien D. Nguyen

Networks of interconnected neurons display diverse patterns of collective activity. Relating this collective activity to the network's connectivity structure is a key goal of computational neuroscience. We approach this question for…

Neurons and Cognition · Quantitative Biology 2025-06-09 Caitlin Lienkaemper , Gabriel Koch Ocker

We address the problem of identifying functional interactions among stochastic neurons with variable-length memory from their spiking activity. The neuronal network is modeled by a stochastic system of interacting point processes with…

Applications · Statistics 2025-07-01 Ricardo F. Ferreira , Matheus E. Pacola , Vitor G. Schiavone , Rodrigo F. O. Pena

We study the problem of clustering nodes in a dynamic graph, where the connections between nodes and nodes' cluster memberships may change over time, e.g., due to community migration. We first propose a dynamic stochastic block model that…

Machine Learning · Computer Science 2021-06-24 Yuhang Yao , Carlee Joe-Wong

The goal of lifetime clustering is to develop an inductive model that maps subjects into $K$ clusters according to their underlying (unobserved) lifetime distribution. We introduce a neural-network based lifetime clustering model that can…

Machine Learning · Computer Science 2019-10-03 S Chandra Mouli , Leonardo Teixeira , Jennifer Neville , Bruno Ribeiro