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Related papers: Flux ratios and channel structures

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This study investigates the flux ratios of ionic flows using Poisson-Nernst-Planck (PNP) models. The flux ratio measures the effect of permanent charge on the ion fluxes and can exhibit bifurcation, where a small parameter change causes a…

Dynamical Systems · Mathematics 2023-11-07 Hamid Mofidi

Ionic flow carries electrical signals for cells to communicate with each other. The permanent charge of an ion channel is a crucial protein structure for flow properties while boundary conditions play a role of the driving force. Their…

Numerical Analysis · Mathematics 2021-06-09 Weizhang Huang , Weishi Liu , Yufei Yu

In this paper, we study effects of permanent charges on ion flows through membrane channels via a quasi-one-dimensional classical Poisson-Nernst-Planck system. This system includes three ion species, two cations with different valences and…

Soft Condensed Matter · Physics 2023-12-07 Ning Sun , Weishi Liu

In this paper, based on geometric singular perturbation analysis of a quasi-one dimensional Poisson-Nernst-Planck model for ionic flows, we study the problem of zero current condition for ionic flows through membrane channels with a simple…

Dynamical Systems · Mathematics 2020-09-22 Hamid Mofidi , Weishi Liu

In this work, the dependence of reversal potentials and zero-current fluxes on diffusion coefficients are examined for ionic flows through membrane channels. The study is conducted for the setup of a simple structure defined by the profile…

Soft Condensed Matter · Physics 2019-12-17 Bob Eisenberg , Weishi Liu , Hamid Mofidi

Ion channels are of major interest and form an area of intensive research in the fields of biophysics and medicine since they control many vital physiological functions. The aim of this work is on one hand to propose a fully stochastic and…

Biomolecules · Quantitative Biology 2016-01-11 Daniela Morale , Mattia Zanella , Vincenzo Capasso , Willi Jaeger

The main goal of this work is to examine the qualitative effect of ion sizes via a steady-state boundary value problem. We study a one-dimensional version of a Poisson-Nernst-Planck system with a local hard-sphere potential model for ionic…

Mathematical Physics · Physics 2022-03-18 Weishi Liu , Hamid Mofidi

We investigate the effects of the relative dielectric coefficient on ionic flows in open ion channels, using mathematical analysis of reasonably general Poisson-Nernst-Planck type models that can include the finite sizes of ions. The value…

Biomolecules · Quantitative Biology 2017-10-03 Bob Eisenberg , Weishi Liu

We discuss various models of ion transport through cell membrane channels. Recent experimental data shows that sizes of ion channels are compared to those of ions and that only few ions may be simultaneously in any single channel.…

Subcellular Processes · Quantitative Biology 2007-06-06 Jan Gomulkiewicz , Jacek Miekisz , Stanislaw Miekisz

In this work, we examine effects of large permanent charges on ionic flow through ion channels based on a quasi-one dimensional Poisson-Nernst-Planck model. It turns out large positive permanent charges inhibit the flux of cation as…

Quantitative Methods · Quantitative Biology 2017-12-20 Liwei Zhang , Bob Eisenberg , Weishi Liu

In this research, we explore how permanent charges affect the movement of ionic currents through ion channels. We use a quasi-one-dimensional classical Poisson-Nernst-Planck (PNP) model to study two types of ions, one positively charged and…

Dynamical Systems · Mathematics 2023-12-29 Hamid Mofidi

The molecular mechanism of ion channel gating and substrate modulation is elusive for many voltage gated ion channels, such as eukaryotic sodium ones. The understanding of channel functions is a pressing issue in molecular biophysics and…

Biomolecules · Quantitative Biology 2016-11-15 Duan Chen , Guowei Wei

The high order fluid model developed in the preceding paper is employed here to study the propagation of negative planar streamer fronts in pure nitrogen. The model consists of the balance equations for electron density, average electron…

Plasma Physics · Physics 2013-11-13 A. H. Markosyan , S. Dujko , U. Ebert

Electrochemical cells serve as a building block for producing and storing electrical energy from chemical reactions. The analysis of ion transport in these systems forms the foundation for understanding more complex electrochemical systems…

Chemical Physics · Physics 2026-02-05 Grace Origer , Ritu R. Raj , Nathan Jarvey , P. N. Romero Zavala , Wilson A. Smith , Ankur Gupta

A Poisson-Nernst-Planck-Fermi (PNPF) theory is developed for studying ionic transport through biological ion channels. Our goal is to deal with the finite size of particle using a Fermi like distribution without calculating the forces…

Biological Physics · Physics 2015-06-23 Jinn-Liang Liu , Bob Eisenberg

Effective Poisson-Nernst-Planck (PNP) equations are derived for macroscopic ion transport in charged porous media under periodic fluid flow by an asymptotic multi-scale expansion with drift. The microscopic setting is a two-component…

Mathematical Physics · Physics 2014-07-16 Markus Schmuck , Martin Z. Bazant

We present a method to compute transport coefficients in molecular dynamics. Transport coefficients quantify the linear dependencies of fluxes in non-equilibrium systems subject to small external forcings. Whereas standard non-equilibrium…

Statistical Mechanics · Physics 2023-05-17 Noé Blassel , Gabriel Stoltz

A discrete rate theory for general multi-ion channels is presented, in which the continuous dynamics of ion diffusion is reduced to transitions between Markovian discrete states. In an open channel, the ion permeation process involves three…

Biological Physics · Physics 2012-06-29 Wan Chen , Radek Erban , S. Jonathan Chapman

A stochastic approach for charge transport in diodes is developed in consistency with the laws of electricity, thermodynamics, and microreversibility. In this approach, the electron and hole densities are ruled by diffusion-reaction…

Statistical Mechanics · Physics 2018-06-06 Jiayin Gu , Pierre Gaspard

This work examines the geometric mean of concentrations and its behavior in various situations, as well as the reversal permanent charge problem, the charge sharing seen in x-ray diffraction. Observations are obtained from analytical…

Statistical Mechanics · Physics 2020-09-22 Hamid Mofidi
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