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In the paper the interval least squares approach to estimate/fit data with interval uncertainties is introduced. The solution of this problem is discussed from the perspective of interval linear algebra. Using the interval linear algebra…

Quantitative Methods · Quantitative Biology 2019-02-26 Jaroslav Horáček , Václav Koucký , Milan Hladík

Substudies of the Childhood Asthma Management Program [Control. Clin. Trials 20 (1999) 91-120; N. Engl. J. Med. 343 (2000) 1054-1063] seek to identify patient characteristics associated with asthma symptoms and lung function. To determine…

Background: The most widely used approach to joint modelling of repeated measurement and time to event data is to combine a linear Gaussian random effects model for the repeated measurements with a log-Gaussian frailty model for the…

Methodology · Statistics 2016-09-12 Elisabeth Waldmann , David Taylor-Robinson

Determining the best model or models for a particular data set, a process known as Bayesian model comparison, is a critical part of probabilistic inference. Typically, this process assumes a fixed model-space (that is, a fixed set of…

Quantitative Methods · Quantitative Biology 2019-01-08 Thomas HB FitzGerald , Dorothea Hammerer , Thomas D Sambrook , Will D Penny

Breath analysis has emerged as a critical tool in health monitoring, offering insights into respiratory function, disease detection, and continuous health assessment. While traditional contact-based methods are reliable, they often pose…

Machine Learning · Computer Science 2025-08-14 Almustapha A. Wakili , Babajide J. Asaju , Woosub Jung

Quantitative analysis of fetal lung Diffusion-Weighted MRI (DWI) data shows potential in providing quantitative imaging biomarkers that indirectly reflect fetal lung maturation. However, fetal motion during the acquisition hampered…

Computer Vision and Pattern Recognition · Computer Science 2022-08-23 Yael Zaffrani-Reznikov , Onur Afacan , Sila Kurugol , Simon Warfield , Moti Freiman

Non-invasive ventilation is increasingly used for respiratory support in preterm infants, and is associated with a lower risk of chronic lung disease. However, this mode is often not successful in the extremely preterm infant in part due to…

Tissues and Organs · Quantitative Biology 2018-07-04 Laura Ellwein Fix , Joseph Khoury , Russell Moores , Lauren Linkous , Matthew Brandes , Henry J. Rozycki

Count outcomes in longitudinal studies are frequent in clinical and engineering studies. In frequentist and Bayesian statistical analysis, methods such as Mixed linear models allow the variability or correlation within individuals to be…

Methodology · Statistics 2024-07-15 Alejandra Estefanía Patiño Hoyos , Johnatan Cardona Jiménez

This paper introduces the modeling of circular data with excess zeros under a longitudinal framework, where the response is a circular variable and the covariates can be both linear and circular in nature. In the literature, various…

Methodology · Statistics 2026-01-21 Prajamitra Bhuyan , Soutik Halder , Jayant Jha

Human respiratory rate and its pattern convey essential information about the physical and psychological states of the subject. Abnormal breathing can indicate fatal health issues leading to further diagnosis and treatment. Wireless…

Signal Processing · Electrical Eng. & Systems 2024-04-17 Md Zobaer Islam , Brenden Martin , Carly Gotcher , Tyler Martinez , John F. O'Hara , Sabit Ekin

We review some aspects of Bayesian and frequentist interval estimation, focusing first on their relative strengths and weaknesses when used in "clean" or "textbook" contexts. We then turn attention to observational-data situations which are…

Methodology · Statistics 2010-10-05 Paul Gustafson , Sander Greenland

Pathological assessment guides lung cancer diagnosis, treatment selection, and prognostic evaluation, yet current CPath approaches rely on task-specific models for isolated objectives. Although pan-cancer foundation models offer…

Bayesian estimation is increasingly popular for performing model based inference to support policymaking. These data are often collected from surveys under informative sampling designs where subject inclusion probabilities are designed to…

Methodology · Statistics 2018-07-13 Luis G. Leon-Novelo , Terrance D. Savitsky

A series of experiments in stationary and moving passenger rail cars were conducted to measure removal rates of particles in the size ranges of SARS-CoV-2 viral aerosols, and the air changes per hour provided by existing and modified air…

Methodology · Statistics 2024-06-28 Soumyakanti Pan , Darpan Das , Gurumurthy Ramachandran , Sudipto Banerjee

Joint models for longitudinal and survival data have become a popular framework for studying the association between repeatedly measured biomarkers and clinical events. Nevertheless, addressing complex survival data structures, especially…

A Bayesian multiple change-point model is proposed to analyse violations of air quality standards by pollutants such as nitrogen oxides (NO2 and NO) and carbon monoxide (CO). The model is built on the assumption that the occurrence of…

Applications · Statistics 2010-12-10 Janos Gyarmati-Szabo , Leonid V. Bogachev , Haibo Chen

The purpose of this study is to provide means to physicians for automated and fast recognition of airways diseases. In this work, we mainly focus on measures that can be easily recorded using a spirometer. The signals used in this framework…

Machine Learning · Computer Science 2021-11-09 Riccardo Dio , André Galligo , Angelos Mantzaflaris , Benjamin Mauroy

This paper describes a method for a model-based analysis of clinical safety data called multivariate Bayesian logistic regression (MBLR). Parallel logistic regression models are fit to a set of medically related issues, or response…

Methodology · Statistics 2012-10-02 William DuMouchel

The win ratio (WR) statistic is increasingly used to evaluate treatment effects based on prioritized composite endpoints, yet existing Bayesian adaptive designs are not directly applicable because the WR is a summary statistic derived from…

Methodology · Statistics 2026-02-20 Di Zhu , Yong Zang

Frequentist statistical methods, such as hypothesis testing, are standard practice in papers that provide benchmark comparisons. Unfortunately, these methods have often been misused, e.g., without testing for their statistical test…

Methodology · Statistics 2021-05-18 David Issa Mattos , Jan Bosch , Helena Holmström Olsson
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