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Disease phenotyping algorithms process observational clinical data to identify patients with specific diseases. Supervised phenotyping methods require significant quantities of expert-labeled data, while unsupervised methods may learn…

Machine Learning · Computer Science 2019-03-27 Victor Rodriguez , Adler Perotte

Predicting phenotypes from gene expression data is a crucial task in biomedical research, enabling insights into disease mechanisms, drug responses, and personalized medicine. Traditional machine learning and deep learning rely on…

Machine Learning · Computer Science 2025-09-18 Kevin Dradjat , Massinissa Hamidi , Pierre Bartet , Blaise Hanczar

The extraction of phenotype information which is naturally contained in electronic health records (EHRs) has been found to be useful in various clinical informatics applications such as disease diagnosis. However, due to imprecise…

Computation and Language · Computer Science 2019-11-12 Jingqing Zhang , Xiaoyu Zhang , Kai Sun , Xian Yang , Chengliang Dai , Yike Guo

This article reviews recent advances in applying natural language processing (NLP) to Electronic Health Records (EHRs) for computational phenotyping. NLP-based computational phenotyping has numerous applications including diagnosis…

Computation and Language · Computer Science 2018-06-18 Zexian Zeng , Yu Deng , Xiaoyu Li , Tristan Naumann , Yuan Luo

Mining electronic health records for patients who satisfy a set of predefined criteria is known in medical informatics as phenotyping. Phenotyping has numerous applications such as outcome prediction, clinical trial recruitment, and…

Computation and Language · Computer Science 2018-05-08 Dmitriy Dligach , Timothy Miller

Extracting phenotypes from clinical text has been shown to be useful for a variety of clinical use cases such as identifying patients with rare diseases. However, reasoning with numerical values remains challenging for phenotyping in…

Computation and Language · Computer Science 2022-04-22 Ashwani Tanwar , Jingqing Zhang , Julia Ive , Vibhor Gupta , Yike Guo

Medical image analysis using supervised deep learning methods remains problematic because of the reliance of deep learning methods on large amounts of labelled training data. Although medical imaging data repositories continue to expand…

Computer Vision and Pattern Recognition · Computer Science 2019-06-11 Euijoon Ahn , Ashnil Kumar , Dagan Feng , Michael Fulham , Jinman Kim

We propose a method to facilitate exploration and analysis of new large data sets. In particular, we give an unsupervised deep learning approach to learning a latent representation that captures semantic similarity in the data set. The core…

Computer Vision and Pattern Recognition · Computer Science 2020-12-23 Gary B Huang , Huei-Fang Yang , Shin-ya Takemura , Pat Rivlin , Stephen M Plaza

Understanding patterns of diagnoses, medications, procedures, and laboratory tests from electronic health records (EHRs) and health insurer claims is important for understanding disease risk and for efficient clinical development, which…

Machine Learning · Computer Science 2022-11-16 Ying Xu , Romane Gauriau , Anna Decker , Jacob Oppenheim

Semi-supervised learning via learning from limited quantities of labeled data has been investigated as an alternative to supervised counterparts. Maximizing knowledge gains from copious unlabeled data benefit semi-supervised learning…

Computer Vision and Pattern Recognition · Computer Science 2021-04-02 Ayaan Haque , Abdullah-Al-Zubaer Imran , Adam Wang , Demetri Terzopoulos

Exponential growth in Electronic Healthcare Records (EHR) has resulted in new opportunities and urgent needs for discovery of meaningful data-driven representations and patterns of diseases in Computational Phenotyping research. Deep…

Machine Learning · Statistics 2015-12-14 Zhengping Che , Sanjay Purushotham , Robinder Khemani , Yan Liu

Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

Phenotyping consists in applying algorithms to identify individuals associated with a specific, potentially complex, trait or condition, typically out of a collection of Electronic Health Records (EHRs). Because a lot of the clinical…

Interpretation of medical images for diagnosis and treatment of complex disease from high-dimensional and heterogeneous data remains a key challenge in transforming healthcare. In the last few years, both supervised and unsupervised deep…

Image and Video Processing · Electrical Eng. & Systems 2018-12-20 Khalid Raza , Nripendra Kumar Singh

Within the intensive care unit (ICU), a wealth of patient data, including clinical measurements and clinical notes, is readily available. This data is a valuable resource for comprehending patient health and informing medical decisions, but…

Machine Learning · Computer Science 2023-12-13 Ryan King , Tianbao Yang , Bobak Mortazavi

Pre-training has shown success in different areas of machine learning, such as Computer Vision (CV), Natural Language Processing (NLP) and medical imaging. However, it has not been fully explored for clinical data analysis. Even though an…

Machine Learning · Computer Science 2022-06-10 Chantal Pellegrini , Anees Kazi , Nassir Navab

Unsupervised domain adaptation aims to address the problem of classifying unlabeled samples from the target domain whilst labeled samples are only available from the source domain and the data distributions are different in these two…

Machine Learning · Computer Science 2019-11-20 Qian Wang , Toby P. Breckon

Semisupervised learning is a learning standard which deals with the study of how computers and natural systems such as human beings acquire knowledge in the presence of both labeled and unlabeled data. Semisupervised learning based methods…

Machine Learning · Computer Science 2014-02-20 V. Jothi Prakash , Dr. L. M. Nithya

Current machine learning has made great progress on computer vision and many other fields attributed to the large amount of high-quality training samples, while it does not work very well on genomic data analysis, since they are notoriously…

Machine Learning · Computer Science 2020-09-04 Ziyi Yang , Jun Shu , Yong Liang , Deyu Meng , Zongben Xu

Identifying a patient's key problems over time is a common task for providers at the point care, yet a complex and time-consuming activity given current electric health records. To enable a problem-oriented summarizer to identify a…

Applications · Statistics 2020-03-26 Gal Levy-Fix , Jason Zucker , Konstantin Stojanovic , Noémie Elhadad
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