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In deep tissue photoacoustic imaging, the spatial resolution is inherently limited by acoustic diffraction. Moreover, as the ultrasound attenuation increases with frequency, resolution is often traded-off for penetration depth. Here we…

In deep tissue photoacoustic imaging the spatial resolution is inherently limited by the acoustic wavelength. We present an approach for surpassing the acoustic diffraction limit by exploiting temporal fluctuations in the sample absorption…

Optics · Physics 2017-05-31 Thomas Chaigne , Bastien Arnal , Sergey Vilov , Emmanuel Bossy , Ori Katz

Optical scattering presents a major obstacle to high resolution imaging in biological tissue and other turbid media. Conventional photoacoustic imaging can partially overcome this obstacle, enabling imaging of optical absorption in the…

The resolution of photoacoustic imaging deep inside scattering media is limited by the acoustic diffraction limit. In this work, taking inspiration from super-resolution imaging techniques developed to beat the optical diffraction limit, we…

Optics · Physics 2017-11-15 Sergey Vilov , Bastien Arnal , Emmanuel Bossy

In this tutorial, we aim to directly recreate some of our "aha" moments when exploring the impact of heat diffusion on the spatial resolution limit of photothermal imaging. Our objective is also to communicate how this physical limit can…

Numerical Analysis · Mathematics 2023-10-24 Peter Burgholzer , Johannes Bauer-Marschallinger , Mike Hettich , Markus Haltmeier

Photoacoustic tomography is an emerging medical imaging technology whose primary aim is to map the high-contrast optical properties of biological tissues by leveraging high-resolution ultrasound measurements. Mathematically, this can be…

Analysis of PDEs · Mathematics 2025-02-14 Alessandro Felisi

In high-frequency photoacoustic imaging with uniform illumination, homogeneous photo-absorbing structures may be invisible because of their large size or limited-view issues. Here we show that, by exploiting dynamic speckle illumination, it…

Optics · Physics 2013-12-03 Jérôme Gateau , Thomas Chaigne , Ori Katz , Sylvain Gigan , Emmanuel Bossy

Photoacoustic imaging is the leading technique for deep tissue optical imaging, allowing single-shot imaging at depths. However, its resolution may be limited by acoustic aberrations, caused by natural unknown heterogeneities in the tissue…

Optics · Physics 2026-05-01 Yevgeny Slobodkin , Ori Katz

Photoacoustic tomography is a hybrid biomedical technology, which combines the advantages of acoustic and optical imaging. However, for the conventional image reconstruction method, the image quality is affected obviously by artifacts under…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Bowei Yao , Yi Zeng , Haizhao Dai , Qing Wu , Youshen Xiao , Fei Gao , Yuyao Zhang , Jingyi Yu , Xiran Cai

In this paper we consider a mathematical model for photoacoustic imaging which takes into account attenuation due to thermodynamic dissipation. The propagation of acoustic (compressional) waves is governed by a scalar wave equation coupled…

Analysis of PDEs · Mathematics 2016-10-12 Sebastian Acosta , Carlos Montalto

Optical microscopy has so far been restricted to superficial layers, leaving many important biological questions unanswered. Random scattering causes the ballistic focus, which is conventionally used for image formation, to decay…

Optics · Physics 2012-08-28 Ke Si , Reto Fiolka , Meng Cui

Imaging through opaque, highly scattering walls is a long sought after capability with potential applications in a variety of fields. The use of wavefront shaping to compensate for scattering has brought a renewed interest as a potential…

Almost all known image reconstruction algorithms for photoacoustic and thermoacoustic tomography assume that the acoustic waves leave the region of interest after a finite time. This assumption is reasonable if the reflections from the…

Analysis of PDEs · Mathematics 2015-06-16 L. Kunyansky , B. Holman , B. T. Cox

Photo-acoustic tomography is a newly developed hybrid imaging modality that combines a high-resolution modality with a high-contrast modality. We analyze the reconstruction of diffusion and absorption parameters in an elliptic equation and…

Analysis of PDEs · Mathematics 2015-06-04 Jie Chen , Yang Yang

Photoacoustic (PA) imaging is a biomedical imaging modality capable of acquiring high-contrast images of optical absorption at depths much greater than traditional optical imaging techniques. However, practical instrumentation and geometry…

Computer Vision and Pattern Recognition · Computer Science 2021-06-02 Mengjie Guo , Hengrong Lan , Changchun Yang , Fei Gao

In this tutorial, we combine the different scientific fields of information theory, thermodynamics, regularization theory and non-destructive imaging, especially for photoacoustic and photothermal imaging. The goal is to get a better…

Applied Physics · Physics 2020-12-02 Peter Burgholzer , Guenther Mayr , Gregor Thummerer , Markus Haltmeier

In this paper, we present a novel reconstruction method for diffuse optical spectroscopic imaging with a commonly used tissue model of optical absorption and scattering. It is based on linearization and group sparsity, which allows…

Numerical Analysis · Mathematics 2019-03-06 Habib Ammari , Bangti Jin , Wenlong Zhang

A crucial limitation of current high-resolution 3D photoacoustic tomography (PAT) devices that employ sequential scanning is their long acquisition time. In previous work, we demonstrated how to use compressed sensing techniques to improve…

Numerical Analysis · Mathematics 2020-09-07 Felix Lucka , Nam Huynh , Marta Betcke , Edward Zhang , Paul Beard , Ben Cox , Simon Arridge

Acousto-optic tomography (AOT) enables optical-contrast imaging deep inside scattering samples via localized ultrasound modulation of scattered light. However, the resolution of AOT is inherently limited by the ultrasound focus size,…

Optics · Physics 2018-12-12 Daniel Doktofsky , Moriya Rosenfeld , Ori Katz

In this paper we consider the problem of acoustic inversion in the context of the optoacoustic tomography image reconstruction problem. By leveraging the ability of the recently proposed diffusion models for image generative tasks among…

Image and Video Processing · Electrical Eng. & Systems 2024-04-17 M. G. González , M. Vera , A. Dreszman , L. J. Rey Vega
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