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The relationship between the dynamics of a community and its constituent pairwise interactions is a fundamental problem in ecology. Higher-order ecological effects beyond pairwise interactions may be key to complex ecosystems, but…

Populations and Evolution · Quantitative Biology 2018-09-05 Michael Manhart , Eugene I. Shakhnovich

Microbial populations generally evolve in volatile environments, under conditions fluctuating between harsh and mild, e.g. as the result of sudden changes in toxin concentration or nutrient abundance. Environmental variability thus shapes…

Populations and Evolution · Quantitative Biology 2023-12-07 Matthew Asker , Lluís Hernández-Navarro , Alastair M. Rucklidge , Mauro Mobilia

Speciation is driven by many different factors. Among those are trade-offs between different ways an organism utilizes resources, and these trade-offs can constrain the manner in which selection can optimize traits. Limited migration among…

Populations and Evolution · Quantitative Biology 2014-08-12 Bjørn Østman , Randall Lin , Christoph Adami

Phase variation, or stochastic switching between alternative states of gene expression, is common among microbes, and may be important in coping with changing environments. We use a theoretical model to assess whether such switching is a…

Populations and Evolution · Quantitative Biology 2010-04-13 Paolo Visco , Rosalind J. Allen , Satya N. Majumdar , Martin R. Evans

The role of the selection pressure and mutation amplitude on the behavior of a single-species population evolving on a two-dimensional lattice, in a periodically changing environment, is studied both analytically and numerically. The…

Populations and Evolution · Quantitative Biology 2009-11-13 Ioana Bena , Michel Droz , Janusz Szwabinski , Andrzej Pekalski

The evolution of antimicrobial resistance generally occurs in an environment where antimicrobial concentration is variable, which has dramatic consequences on the microorganisms' fitness landscape, and thus on the evolution of resistance.…

Biological Physics · Physics 2018-10-23 Loïc Marrec , Anne-Florence Bitbol

Stochastic phenotype switching has been suggested to play a beneficial role in microbial populations by leading to the division of labour among cells, or ensuring that at least some of the population survives an unexpected change in…

Populations and Evolution · Quantitative Biology 2016-02-02 Andrew C. Tadrowski , Martin R. Evans , Bartlomiej Waclaw

Microbial adaptation to extreme stress, such as starvation, antimicrobial exposure, or freezing often reveals fundamental trade-offs between survival and proliferation. Understanding how populations navigate these trade-offs in fluctuating…

Populations and Evolution · Quantitative Biology 2026-05-12 Nandita Chaturvedi , Charuhansini Tvishamayi , Shashi Thutupalli

We study the evolution of recombination using a microscopic model developed within the frame of the theory of quantitative traits. Two components of fitness are considered: a static one that describes adaptation to environmental factors not…

Populations and Evolution · Quantitative Biology 2007-05-23 Franco Bagnoli , Carlo Guardiani

Intraspecific trait variation has been increasingly recognized as an important factor in determining species interaction and diversity. Eco-evolutionary models have studied the distribution of trait values within a population that changes…

Populations and Evolution · Quantitative Biology 2023-10-12 Zachary Jackson , BingKan Xue

Living species, ranging from bacteria to animals, exist in environmental conditions that exhibit spatial and temporal heterogeneity which requires them to adapt. Risk-spreading through spontaneous phenotypic variations is a known concept in…

Populations and Evolution · Quantitative Biology 2020-04-03 Aleksandra Ardaševa , Robert A. Gatenby , Alexander R. A. Anderson , Helen M. Byrne , Philip K. Maini , Tommaso Lorenzi

There is a pressing need to better understand how microbial populations respond to antimicrobial drugs, and to find mechanisms to possibly eradicate antimicrobial-resistant cells. The inactivation of antimicrobials by resistant microbes can…

Populations and Evolution · Quantitative Biology 2023-11-16 Lluís Hernández-Navarro , Matthew Asker , Alastair M. Rucklidge , Mauro Mobilia

We study the interplay of population growth and evolutionary dynamics using a stochastic model based on birth and death events. In contrast to the common assumption of an independent population size, evolution can be strongly affected by…

Populations and Evolution · Quantitative Biology 2012-06-05 Jonas Cremer , Anna Melbinger , Erwin Frey

Environment plays a fundamental role in the competition for resources, and hence in the evolution of populations. Here, we study a well-mixed, finite population consisting of two strains competing for the limited resources provided by an…

Populations and Evolution · Quantitative Biology 2017-10-16 Karl Wienand , Erwin Frey , Mauro Mobilia

Non-selective effects, like genetic drift, are an important factor in modern conceptions of evolution, and have been extensively studied for constant population sizes. Here, we consider non-selective evolution in the case of growing…

Populations and Evolution · Quantitative Biology 2017-09-04 Karl Wienand , Matthias Lechner , Felix Becker , Heinrich Jung , Erwin Frey

Predicting the adaptation of populations to a changing environment is crucial to assess the impact of human activities on biodiversity. Many theoretical studies have tackled this issue by modeling the evolution of quantitative traits…

Analysis of PDEs · Mathematics 2022-06-28 Jimmy Garnier , O Cotto , T Bourgeron , E Bouin , T Lepoutre , O Ronce , V Calvez

Environmental changes greatly influence the evolution of populations. Here, we study the dynamics of a population of two strains, one growing slightly faster than the other, competing for resources in a time-varying binary environment…

Populations and Evolution · Quantitative Biology 2020-07-28 Ami Taitelbaum , Robert West , Michael Assaf , Mauro Mobilia

Microbes providing public goods are widespread in nature despite running the risk of being exploited by free-riders. However, the precise ecological factors supporting cooperation are still puzzling. Following recent experiments, we…

Populations and Evolution · Quantitative Biology 2012-03-28 Jonas Cremer , Anna Melbinger , Erwin Frey

Using Monte Carlo model of biological evolution we have discovered that populations can switch between two different strategies of their genomes' evolution; Darwinian purifying selection and complementing the haplotypes. The first one is…

Populations and Evolution · Quantitative Biology 2009-11-13 Marta Zawierta , Wojciech Waga , Dorota Mackiewicz , Przemyslaw Biecek , Stanislaw Cebrat

During bouts of evolutionary diversification, such as adaptive radiations, the emerging species cluster around different locations in phenotype space, How such multimodal patterns in phenotype space can emerge from a single ancestral…

Populations and Evolution · Quantitative Biology 2007-11-19 Michael Doebeli , Hendrik J. Blok , Olof Leimar , Ulf Dieckmann
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