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A complex system comprises multiple interacting entities whose interdependencies form a unified whole, exhibiting emergent behaviours not present in individual components. Examples include the human brain, living cells, soft matter, Earth's…

Nonparametric estimation of the mean and covariance functions is ubiquitous in functional data analysis and local linear smoothing techniques are most frequently used. Zhang and Wang (2016) explored different types of asymptotic properties…

Statistics Theory · Mathematics 2025-01-28 Shaojun Guo , Dong Li , Xinghao Qiao , Yizhu Wang

Complex systems are characterized by a huge number of degrees of freedom often interacting in a non-linear manner. In many cases macroscopic states, however, can be characterized by a small number of order parameters that obey stochastic…

Data Analysis, Statistics and Probability · Physics 2012-02-20 David Kleinhans

Integrating high-dimensional biological data into data-driven mechanistic modeling requires rigorous practical identifiability to ensure interpretability and generalizability. However, coordinate identifiability analysis often suffers from…

Quantitative Methods · Quantitative Biology 2026-02-25 Shun Wang , Wenrui Hao

Neural activity patterns related to behavior occur at many scales in time and space from the atomic and molecular to the whole brain. Here we explore the feasibility of interpreting neurophysiological data in the context of many-body…

Other Quantitative Biology · Quantitative Biology 2009-11-11 Walter J. Freeman , Giuseppe Vitiello

An Electroencephalogram (EEG) is a non-invasive exam that records the brain's electrical activity. This is used to help diagnose conditions such as different brain problems. EEG signals are taken for epilepsy detection, and with Discrete…

Machine Learning · Computer Science 2024-05-28 Rabel Guharoy , Nanda Dulal Jana , Suparna Biswas , Lalit Garg

The increasing frequency and severity of climate related disasters have intensified the need for real time monitoring, early warning, and informed decision-making. Earth Observation (EO), powered by satellite data and Machine Learning (ML),…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Stella Girtsou , Konstantinos Alexis , Giorgos Giannopoulos , Charalambos Kontoes

Complex, oscillatory data arises from a large variety of biological, physical, and social systems. However, the inherent oscillation and ubiquitous noise pose great challenges to current methodology such as linear and nonlinear time series…

Chaotic Dynamics · Physics 2008-09-19 J. Zhang , K. Zhang , J. Feng , J. Sun , X. Xu , M. Small

The statistical problem of parameter estimation in partially observed hypoelliptic diffusion processes is naturally occurring in many applications. However, due to the noise structure, where the noise components of the different coordinates…

Methodology · Statistics 2018-11-13 Susanne Ditlevsen , Adeline Samson

Objective: A clinical decision support tool that automatically interprets EEGs can reduce time to diagnosis and enhance real-time applications such as ICU monitoring. Clinicians have indicated that a sensitivity of 95% with a specificity…

Biological oscillations are periodic changes in various signaling processes crucial for the proper functioning of living organisms. These oscillations are modeled by ordinary differential equations, with coefficient variations leading to…

Machine Learning · Computer Science 2024-12-04 Heng Rao , Yu Gu , Jason Zipeng Zhang , Ge Yu , Yang Cao , Minghan Chen

We develop here a stochastic framework for modeling and segmenting transient spindle-like oscillatory bursts in electroencephalogram (EEG) signals. At the modeling level, individual spindles are represented as path realizations of a…

Neurons and Cognition · Quantitative Biology 2025-12-13 C. Sun , D. Fettahoglu , D. Holcman

We consider statistical inference in factor analysis for ergodic and non-ergodic diffusion processes from discrete observations. Factor model based on high frequency time series data has been mainly discussed in the field of high…

Statistics Theory · Mathematics 2022-02-04 Shogo Kusano , Masayuki Uchida

In neuroscience, researchers typically conduct experiments under multiple conditions to acquire neural responses in the form of high-dimensional spike train datasets. Analysing high-dimensional spike data is a challenging statistical…

Machine Learning · Computer Science 2024-10-28 Yididiya Y. Nadew , Xuhui Fan , Christopher J. Quinn

Statistical inference on histograms and frequency counts plays a central role in categorical data analysis. Moving beyond classical methods that directly analyze labeled frequencies, we introduce a framework that models the multiset of…

Statistics Theory · Mathematics 2025-11-10 Yun Ma , Pengkun Yang

In this paper, we study inference for high-dimensional data characterized by small sample sizes relative to the dimension of the data. In particular, we provide an infinite-dimensional framework to study statistical models that involve…

Statistics Theory · Mathematics 2010-02-25 Jim Kuelbs , Anand N. Vidyashankar

The analysis of chaotic signals with time-frequency methods is considered. For this purpose, two new transformations are presented which consist in the decomposition of a signal onto an orthogonal set of respectively linear and hyperbolic…

Chaotic Dynamics · Physics 2010-07-28 Benjamin Ricaud , Francoise Briolle , F. Clairet

Mining time-frequency features is critical for time series forecasting. Existing research has predominantly focused on modeling low-frequency patterns, where most time series energy is concentrated. The overlooking of mid to high frequency…

Machine Learning · Computer Science 2026-03-11 Boya Zhang , Shuaijie Yin , Huiwen Zhu , Xing He

The method of instrumental variables provides a fundamental and practical tool for causal inference in many empirical studies where unmeasured confounding between the treatments and the outcome is present. Modern data such as the genetical…

Methodology · Statistics 2022-10-28 Ziang Niu , Yuwen Gu , Wei Li

In this paper, we evaluate various deep learning frameworks for detecting respiratory anomalies from input audio recordings. To this end, we firstly transform audio respiratory cycles collected from patients into spectrograms where both…

Sound · Computer Science 2022-01-11 Lam Pham , Dat Ngo , Truong Hoang , Alexander Schindler , Ian McLoughlin
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