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We develop a Bayesian inference method for diffusions observed discretely and with noise, which is free of discretisation bias. Unlike existing unbiased inference methods, our method does not rely on exact simulation techniques. Instead,…

Methodology · Statistics 2021-03-10 Neil K. Chada , Jordan Franks , Ajay Jasra , Kody J. H. Law , Matti Vihola

Purpose: Previous quantitative MR imaging studies using self-supervised deep learning have reported biased parameter estimates at low SNR. Such systematic errors arise from the choice of Mean Squared Error (MSE) loss function for network…

Machine Learning · Computer Science 2025-09-25 Christopher S. Parker , Anna Schroder , Sean C. Epstein , James Cole , Daniel C. Alexander , Hui Zhang

Conventional frequentist learning, as assumed by existing federated learning protocols, is limited in its ability to quantify uncertainty, incorporate prior knowledge, guide active learning, and enable continual learning. Bayesian learning…

Information Theory · Computer Science 2021-08-31 Dongzhu Liu , Osvaldo Simeone

We consider the situation where a temporal process is composed of contiguous segments with differing slopes and replicated noise-corrupted time series measurements are observed. The unknown mean of the data generating process is modelled as…

Diffusion magnetic resonance imaging (diffusion MRI) is a non-invasive microstructure assessment technique. Scalar measures, such as FA (fractional anisotropy) and MD (mean diffusivity), quantifying micro-structural tissue properties can be…

Computer Vision and Pattern Recognition · Computer Science 2019-07-23 Xuan Gu , Hans Knutsson , Markus Nilsson , Anders Eklund

Effective connectivity analysis provides an understanding of the functional organization of the brain by studying how activated regions influence one other. We propose a nonparametric Bayesian approach to model effective connectivity…

Applications · Statistics 2011-07-22 Sourabh Bhattacharya , Ranjan Maitra

We propose a pointwise inference algorithm for high-dimensional linear models with time-varying coefficients. The method is based on a novel combination of the nonparametric kernel smoothing technique and a Lasso bias-corrected ridge…

Methodology · Statistics 2017-03-17 Xiaohui Chen , Yifeng He

This study extends the Bayesian nonparametric instrumental variable regression model to determine the structural effects of covariates on the conditional quantile of the response variable. The error distribution is nonparametrically…

Methodology · Statistics 2016-08-30 Genya Kobayashi , Kota Ogasawara

We propose a new highly flexible and tractable Bayesian approach to undertake variable selection in non-Gaussian regression models. It uses a copula decomposition for the joint distribution of observations on the dependent variable. This…

Methodology · Statistics 2020-09-07 Nadja Klein , Michael Stanley Smith

We present a comparison between various algorithms of inference of covariance and precision matrices in small datasets of real vectors, of the typical length and dimension of human brain activity time series retrieved by functional Magnetic…

Statistical Mechanics · Physics 2023-02-07 Miguel Ibáñez-Berganza , Carlo Lucibello , Francesca Santucci , Tommaso Gili , Andrea Gabrielli

In this article we consider Bayesian estimation of static parameters for a class of partially observed McKean-Vlasov diffusion processes with discrete-time observations over a fixed time interval. This problem features several obstacles to…

Computation · Statistics 2025-04-23 Ajay Jasra , Amin Wu

Functional magnetic resonance imaging (fMRI) is a neuroimaging technique known for its ability to capture brain activity non-invasively and at fine spatial resolution (2-3mm). Cortical surface fMRI (cs-fMRI) is a recent development of fMRI…

Applications · Statistics 2023-12-29 Huy Dang , Marzia Cremona , Nicole Lazar , Francesca Chiaromonte

Non-invasive brain stimulation, such as transcranial alternating current stimulation (tACS) provides a powerful tool to directly modulate brain oscillations that mediate complex cognitive processes. While the body of evidence about the…

Perfusion-weighted magnetic resonance imaging (MRI) is an imaging technique that allows one to measure tissue perfusion in an organ of interest through the injection of an intravascular paramagnetic contrast agent (CA). Due to a preference…

Computer Vision and Pattern Recognition · Computer Science 2017-08-28 Cagdas Ulas , Christine Preibisch , Jonathan Sperl , Thomas Pyka , Jayashree Kalpathy-Cramer , Bjoern Menze

Identifying the parameters of a non-linear model that best explain observed data is a core task across scientific fields. When such models rely on complex simulators, evaluating the likelihood is typically intractable, making traditional…

Diffusion models (DMs) have recently shown remarkable performance on inverse problems (IPs). Optimization-based methods can fast solve IPs using DMs as powerful regularizers, but they are susceptible to local minima and noise overfitting.…

Machine Learning · Computer Science 2026-04-21 Yingzhi Xia , Setthakorn Tanomkiattikun , Liangli Zhen , Zaiwang Gu

Modeling magnitude Magnetic Resonance Images (MRI) rician denoising in a Bayesian or generalized Tikhonov framework using Total Variation (TV) leads naturally to the consideration of nonlinear elliptic equations. These involve the so called…

Analysis of PDEs · Mathematics 2018-11-27 Adrian Martin , Emanuele Schiavi , Sergio Segura de Leon

We introduce a novel class of Bayesian mixtures for normal linear regression models which incorporates a further Gaussian random component for the distribution of the predictor variables. The proposed cluster-weighted model aims to…

Methodology · Statistics 2026-05-26 Panagiotis Papastamoulis , Konstantinos Perrakis

Diffusion Magnetic Resonance Imaging (dMRI) is an imaging technique with exquisite sensitivity to the microstructural properties of heterogeneous media. The conventionally adopted acquisition schemes involving single pulsed field gradients…

Biological Physics · Physics 2023-01-04 Deneb Boito , Cem Yolcu , Evren Özarslan

Optimal extraction of cosmological information from observations of the Cosmic Microwave Background critically relies on our ability to accurately undo the distortions caused by weak gravitational lensing. In this work, we demonstrate the…

Cosmology and Nongalactic Astrophysics · Physics 2024-06-07 Thomas Flöss , William R. Coulton , Adriaan J. Duivenvoorden , Francisco Villaescusa-Navarro , Benjamin D. Wandelt
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