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Axonal damage is the primary pathological correlate of long-term impairment in multiple sclerosis (MS). Previous work has demonstrated a strong, quantitative relationship between decrease in axial diffusivity and axonal damage. In the…

Computational Engineering, Finance, and Science · Computer Science 2024-10-15 Nand Sharma

Functional magnetic resonance imaging (fMRI) data have become increasingly available and are useful for describing functional connectivity (FC), the relatedness of neuronal activity in regions of the brain. This FC of the brain provides…

Machine Learning · Statistics 2020-10-14 Andrew DiLernia , Karina Quevedo , Jazmin Camchong , Kelvin Lim , Wei Pan , Lin Zhang

We consider the problem of Bayesian inference for bi-variate data observed in time but with observation times which occur non-synchronously. In particular, this occurs in a wide variety of applications in finance, such as high-frequency…

Methodology · Statistics 2025-03-04 Ajay Jasra , Kengo Kamatani , Amin Wu

Diffusion models have recently shown remarkable results in magnetic resonance imaging reconstruction. However, the employed networks typically are black-box estimators of the (smoothed) prior score with tens of millions of parameters,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-16 Laurenz Nagler , Martin Zach , Thomas Pock

We present a novel way to model diffusion magnetic resonance imaging (dMRI) datasets, that benefits from the structural coherence of the human brain while only using data from a single subject. Current methods model the dMRI signal in…

Image and Video Processing · Electrical Eng. & Systems 2023-08-24 Tom Hendriks , Anna Vilanova , Maxime Chamberland

Functional magnetic resonance imaging or functional MRI (fMRI) is a non-invasive way to assess brain activity by detecting changes associated with blood flow. In this work, we propose a full Bayesian procedure to analyze fMRI data for…

Knowledge of the noise distribution in diffusion MRI is the centerpiece to quantify uncertainties arising from the acquisition process. Accurate estimation beyond textbook distributions often requires information about the acquisition…

Image and Video Processing · Electrical Eng. & Systems 2020-07-07 Samuel St-Jean , Alberto De Luca , Chantal M. W. Tax , Max A. Viergever , Alexander Leemans

Diffusion MRI (dMRI) is a valuable tool in the assessment of tissue microstructure. By fitting a model to the dMRI signal it is possible to derive various quantitative features. Several of the most popular dMRI signal models are expansions…

Neuroimaging meta-analysis is an important tool for finding consistent effects over studies that each usually have 20 or fewer subjects. Interest in meta-analysis in brain mapping is also driven by a recent focus on so-called "reverse…

Applications · Statistics 2014-12-05 Jian Kang , Thomas E. Nichols , Tor D. Wager , Timothy D. Johnson

We propose a novel framework for joint magnetic resonance image reconstruction and uncertainty quantification using under-sampled k-space measurements. The problem is formulated as a Bayesian linear inverse problem, where prior…

Image and Video Processing · Electrical Eng. & Systems 2026-03-17 Ahmed Karam Eldaly , Matteo Figini , Daniel C. Alexander

Diffusion magnetic resonance imaging datasets suffer from low Signal-to-Noise Ratio, especially at high b-values. Acquiring data at high b-values contains relevant information and is now of great interest for microstructural and…

Computer Vision and Pattern Recognition · Computer Science 2016-06-27 Samuel St-Jean , Pierrick Coupé , Maxime Descoteaux

In this article we derive an unbiased expression for the expected mean-squared error associated with continuously differentiable estimators of the noncentrality parameter of a chi-square random variable. We then consider the task of…

Applications · Statistics 2012-10-15 Florian Luisier , Thierry Blu , Patrick J. Wolfe

Recently, score-based diffusion models have shown satisfactory performance in MRI reconstruction. Most of these methods require a large amount of fully sampled MRI data as a training set, which, sometimes, is difficult to acquire in…

Image and Video Processing · Electrical Eng. & Systems 2022-09-05 Zhuo-Xu Cui , Chentao Cao , Shaonan Liu , Qingyong Zhu , Jing Cheng , Haifeng Wang , Yanjie Zhu , Dong Liang

Data-driven modeling of non-Markovian dynamics is a recent topic of research with applications in many fields such as climate research, molecular dynamics, biophysics, or wind power modeling. In the frequently used standard Langevin…

Data Analysis, Statistics and Probability · Physics 2022-07-22 Clemens Willers , Oliver Kamps

Accurate segmentation of brain tumors in MRI scans is essential for reliable clinical diagnosis and effective treatment planning. Recently, diffusion models have demonstrated remarkable effectiveness in image generation and segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-31 Sara Yavari , Rahul Nitin Pandya , Jacob Furst

We propose a novel approach to denoising diffusion magnetic resonance images (dMRI) using convolutional neural networks, that exploits the benefits of data acquired at multiple b-values to offset the need for many redundant observations.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-23 Jakub Jurek , Andrzej Materka , Kamil Ludwisiak , Agata Majos , Filip Szczepankiewicz

This paper presents a new Bayesian model and algorithm for nonlinear unmixing of hyperspectral images. The model proposed represents the pixel reflectances as linear combinations of the endmembers, corrupted by nonlinear (with respect to…

Methodology · Statistics 2015-10-06 Yoann Altmann , Marcelo Pereyra , Stephen McLaughlin

This study examines the optimal selections of bandwidth and semi-metric for a functional partial linear model. Our proposed method begins by estimating the unknown error density using a kernel density estimator of residuals, where the…

Methodology · Statistics 2020-11-17 Han Lin Shang

Very recently, Transformation based Markov Chain Monte Carlo (TMCMC) was proposed by Dutta and Bhattcharya (2013) as a much efficient alternative to the Metropolis-Hastings algorithm, Random Walk Metropolis (RWM) algorithm, especially in…

Computation · Statistics 2017-07-26 Kushal Kr Dey , Sourabh Bhattacharya

Spherical deconvolution (SD) methods are widely used to estimate the intra-voxel white-matter fiber orientations from diffusion MRI data. However, while some of these methods assume a zero-mean Gaussian distribution for the underlying…