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(abridged) We review recent studies of chirality using circularly polarized light, along with the birth and evolution of life and planetary systems. Terrestrial life consists almost exclusively of one enantiomer, left-handed amino acids.…

Astrophysics of Galaxies · Physics 2011-12-08 Tsubasa Fukue

The search for life elsewhere in the universe is a pivotal question in modern science. However, to address whether life is common in the universe we must first understand the likelihood of abiogenesis by studying the origin of life on…

Astrophysics · Physics 2008-11-11 Marcelo Gleiser , Sara Imari Walker

Molecular chirality is critical to biochemical function, but it is unknown when chiral selectivity first became important in the evolutionary transition from geochemistry to biochemistry during the emergence of life. Here, we identify key…

Molecular Networks · Quantitative Biology 2025-05-05 John F. Malloy , Camerian Millsaps , Kamesh Narasimhan , Louie Slocombe , Cole Mathis , Leroy Cronin , Sara Imari Walker

A key open question in the study of life is the origin of biomolecular homochirality: almost every life-form on Earth has exclusively levorotary amino acids and dextrorotary sugars. Will the same handedness be preferred if life is found…

Biomolecules · Quantitative Biology 2015-06-04 Marcelo Gleiser , Sara Imari Walker

Chirality or the property that distinguishes lefthandedness from righthandedness is an important aspect of the universe, starting from neutrinos, which are lefthanded. Fifteen years ago the author had proposed that life on the earth was…

General Physics · Physics 2009-11-01 Burra G. Sidharth

Molecular chirality is inherent to biology and cellular chemistry. In this report, the origin of enantiomeric selectivity is analyzed from the viewpoint of the "RNA World" model, based on the autocatalytic self-replication of glyceraldehyde…

Chemical Physics · Physics 2021-10-26 J. A. Cowan , R. J. Furnstahl

Most biomolecules occur in mirror, or chiral, images of each other. However, life is homochiral: proteins contain almost exclusively levorotatory (L) amino acids, while only dextrorotatory (R) sugars appear in RNA and DNA. The mechanism…

Astrophysics · Physics 2009-06-23 Marcelo Gleiser , Joel Thorarinson , Sara Imari Walker

Many of the building blocks of life such as amino acids and nucleotides are chiral, i.e., different from their mirror image. Contemporary life selects and synthesizes only one of two possible handednesses. In an abiotic environment,…

Biomolecules · Quantitative Biology 2022-09-20 Axel Brandenburg

The article seeks to formulate a synergetic law that is posited to be of common physicochemical and biological nature: an evolving system, possessing free energy and elements with chiral asymmetry may change the type of symmetry inside one…

Adaptation and Self-Organizing Systems · Physics 2012-12-10 Vsevolod A. Tverdislov

In many biological materials with a hierarchical structure there is an intriguing and unique mechanism responsible for the 'propagation' of order from the molecular to the nano- or micro-scale level. Here we present a much simpler molecular…

Chirality is breaking of mirror symmetry in matter. In the fields of biology and chemistry, this is particularly important because some of the essential molecules in life such as amino acids and DNA have chirality. It is a long-standing…

Strongly Correlated Electrons · Physics 2019-07-04 N. Jiang , Y. Nii , H. Arisawa , E. Saitoh , Y. Onose

Living organisms have some common structures, chemical reactions and molecular structures. The organisms consist of cells with cell division, they have homochirality of protein and carbohydrate units, and metabolism, and genetics, and they…

Populations and Evolution · Quantitative Biology 2025-05-27 Søren Toxvaerd

Most amino acids and sugars molecules occur in mirror, or chiral, images of each other, knowns as enantiomers. However, life on Earth is mostly homochiral: proteins contain almost exclusively L-amino acids, while only D-sugars appear in RNA…

Earth and Planetary Astrophysics · Physics 2022-12-29 Marcelo Gleiser

While biologists have not yet reached a consensus on the definition of life, homochirality - the specific molecular handedness of biomolecules - is a phenomenon only produced by life. The unraveling of its origin requires interdisciplinary…

Biological Physics · Physics 2021-10-06 Noemie Globus , Roger D. Blandford , Anatoli Fedynitch

We explore the interplay between tunneling process and chiral interactions in the discrimination of chiral states for an ensemble of molecules in a biological environment. Each molecule is described by an asymmetric double-well potential…

Biomolecules · Quantitative Biology 2017-04-28 Arash Tirandaz , Farhad Taher Ghahramani , Afshin Shafiee

The phenomenon of life is discussed within a framework of its origin as defined by four hypotheses. The 1. hypothesis says: Life, as we know, is (H-C-N-O) based and relies on the number of bulk (Na-Mg-P-S-Cl-K-Ca) and trace elements…

Astrophysics of Galaxies · Physics 2020-11-25 Vlado Valkovic , Jasmina Obhodas

Living organisms exhibit consistent homochirality. It is argued that the specific, binary choice made is not an accident but is a consequence of parity violation in the weak interaction expressed by cosmic irradiation. The secondary muons…

Biological Physics · Physics 2019-11-07 Noemie Globus , Roger D. Blandford

The presence of chirality in the main molecules of life may well be not just a structural artifact, but of pure biological advantage. The possibility of the existence of a phenomenon of a special mode of interaction, labeled as "chiral…

Biological Physics · Physics 2007-05-23 G. Gilat

The emergence and spreading of chirality on the early Earth is considered by studying a set of reaction-diffusion equations based on a polymerization model. It is found that effective mixing of the early oceans is necessary to reach the…

Biomolecules · Quantitative Biology 2015-06-26 Tuomas Multamaki , Axel Brandenburg

In the laboratory, the photo-and thermochemical evolution of ices, made of simple molecules of astrophysical relevance, always leads to the formation of semi-refractory water-soluble organic residues. Targeted searches for specific…

Earth and Planetary Astrophysics · Physics 2019-02-14 Louis D'hendecourt , Paola Modica , Cornelia Meinert , Laurent Nahon , Uwe Meierhenrich
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