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We study counting statistics of number of transitions in a stochastic process. For mesoscopic systems, a path integral formulation for the counting statistics has already been derived. We here show that it is also possible to derive the…

Statistical Mechanics · Physics 2009-07-21 Jun Ohkubo

When monitoring the dynamics of stochastic systems, such as interacting particles agitated by thermal noise, disentangling deterministic forces from Brownian motion is challenging. Indeed, we show that there is an information-theoretic…

Soft Condensed Matter · Physics 2020-04-16 Anna Frishman , Pierre Ronceray

Direct simulation of biomolecular dynamics in thermal equilibrium is challenging due to the metastable nature of conformation dynamics and the computational cost of molecular dynamics. Biased or enhanced sampling methods may improve the…

Chemical Physics · Physics 2015-06-12 Benjamin Trendelkamp-Schroer , Frank Noe

We propose a covariate-dependent discrete graphical model for capturing dynamic networks among discrete random variables, allowing the dependence structure among vertices to vary with covariates. This discrete dynamic network encompasses…

Methodology · Statistics 2025-11-19 Lyndsay Roach , Qiong Li , Nanwei Wang , Xin Gao

This paper describes an algorithm for selecting a consistent set within the consistent histories approach to quantum mechanics and investigates its properties. The algorithm uses a maximum information principle to select from among the…

Quantum Physics · Physics 2009-10-30 Jim McElwaine

We consider a spike-generating stationary Markov process whose transition probabilities are known. We show that there is a canonical potential whose Gibbs distribution, obtained from the Maximum Entropy Principle (MaxEnt), is the…

Neurons and Cognition · Quantitative Biology 2014-01-07 Rodrigo Cofre , Bruno Cessac

Calibration methods have been widely studied in survey sampling over the last decades. Viewing calibration as an inverse problem, we extend the calibration technique by using a maximum entropy method. Finding the optimal weights is achieved…

Methodology · Statistics 2009-09-23 Fabrice Gamboa , Jean-Michel Loubes , Paul Rochet

Inferring the input parameters of simulators from observations is a crucial challenge with applications from epidemiology to molecular dynamics. Here we show a simple approach in the regime of sparse data and approximately correct models,…

Methodology · Statistics 2022-04-06 Rainier Barrett , Mehrad Ansari , Gourab Ghoshal , Andrew D White

Given a complex high-dimensional distribution over $\{\pm 1\}^n$, what is the best way to increase the expected number of $+1$'s by controlling the values of only a small number of variables? Such a problem is known as influence…

Data Structures and Algorithms · Computer Science 2024-01-05 Zongchen Chen , Elchanan Mossel

Adaptive dynamical systems arise in a multitude of contexts, e.g., optimization, control, communications, signal processing, and machine learning. A precise characterization of their fundamental limitations is therefore of paramount…

Information Theory · Computer Science 2010-10-13 Maxim Raginsky

An important challenge in statistical analysis concerns the control of the finite sample bias of estimators. For example, the maximum likelihood estimator has a bias that can result in a significant inferential loss. This problem is…

Statistics Theory · Mathematics 2019-11-04 Stéphane Guerrier , Mucyo Karemera , Samuel Orso , Maria-Pia Victoria-Feser

There are multiple ways in which a stochastic system can be out of statistical equilibrium. It might be subject to time-varying forcing; or be in a transient phase on its way towards equilibrium; it might even be in equilibrium without us…

Dynamical Systems · Mathematics 2019-07-08 Péter Koltai , Hao Wu , Frank Noé , Christof Schütte

The Ising model is a celebrated example of a Markov random field, introduced in statistical physics to model ferromagnetism. This is a discrete exponential family with binary outcomes, where the sufficient statistic involves a quadratic…

Statistics Theory · Mathematics 2021-09-08 Somabha Mukherjee

Integrated Gradients (IG), one of the most popular explainability methods available, still remains ambiguous in the selection of baseline, which may seriously impair the credibility of the explanations. This study proposes a new uniform…

Machine Learning · Computer Science 2022-04-13 Hanxiao Tan

Chemical gradients can be used by a particle to determine its position. This \textit{positional information} is of crucial importance, for example in developmental biology in the formation of patterns in an embryo. The central goal of this…

Statistical Mechanics · Physics 2025-02-21 Prashant Singh , Karel Proesmans

In this paper we develop a novel, discrete-time optimal control framework for mechanical systems with uncertain model parameters. We consider finite-horizon problems where the performance index depends on the statistical moments of the…

Optimization and Control · Mathematics 2017-05-17 George I. Boutselis , Yunpeng Pan , Gerardo De La Tore , Evangelos A. Theodorou

A theory for non-equilibrium systems is derived from a maximum entropy approach similar in spirit to the equilibrium theory given by Gibbs. Requiring Hamilton's principle of stationary action to be satisfied on average during a trajectory,…

Statistical Mechanics · Physics 2019-02-04 David M. Rogers , Susan B. Rempe

It is argued that, for strongly non-linear behaviors, a fully deterministic position can hardly be maintained in the micro-macro transitions. This is due to the lack of information on the relevant boundary conditions, and to the tendency of…

Classical Physics · Physics 2007-05-23 Mayeul Arminjon , Didier Imbault

Empirical force fields employed in molecular dynamics simulations of complex systems can be optimised to reproduce experimentally determined structural and thermodynamic properties. In contrast, experimental knowledge about the rates of…

Statistical Mechanics · Physics 2022-07-12 P. G. Bolhuis , Z. F. Brotzakis , B. G. Keller

MaxEnt inference algorithm and information theory are relevant for the time evolution of macroscopic systems considered as problem of incomplete information. Two different MaxEnt approaches are introduced in this work, both applied to…

Statistical Mechanics · Physics 2012-02-21 Domagoj Kuic , Pasko Zupanovic , Davor Juretic