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In this paper, the flexibility, versatility and predictive power of kernel regression are combined with now lavishly available network data to create regression models with even greater predictive performances. Building from previous work…

Machine Learning · Statistics 2020-11-05 E. Pei , E. Fokoué

Motivation. Cancer heterogeneity is observed at multiple biological levels. To improve our understanding of these differences and their relevance in medicine, approaches to link organ- and tissue-level information from diagnostic images and…

Quantitative Methods · Quantitative Biology 2020-05-19 Nova F. Smedley , Suzie El-Saden , William Hsu

A new modelling approach for the analysis of weighted networks with ordinal/polytomous dyadic values is introduced. Specifically, it is proposed to model the weighted network connectivity structure using a hierarchical multilayer…

Methodology · Statistics 2019-08-05 Alberto Caimo , Isabella Gollini

Traditional classification tasks learn to assign samples to given classes based solely on sample features. This paradigm is evolving to include other sources of information, such as known relations between samples. Here we show that, even…

Machine Learning · Computer Science 2021-04-15 Yifan Qian , Paul Expert , Pietro Panzarasa , Mauricio Barahona

Diffusion-based graph generative models have recently obtained promising results for graph generation. However, existing diffusion-based graph generative models are mostly one-shot generative models that apply Gaussian diffusion in the…

Artificial Intelligence · Computer Science 2023-07-19 Lingkai Kong , Jiaming Cui , Haotian Sun , Yuchen Zhuang , B. Aditya Prakash , Chao Zhang

In this article, we propose a covariance based method for combining partial data sets in the genotype to phenotype spectrum. In particular, an expectation-maximization algorithm that can be used to combine partially overlapping…

Applications · Statistics 2020-01-13 Deniz Akdemir , Julio Isidro Sanchez

Detecting and discovering new gene interactions based on known gene expressions and gene interaction data presents a significant challenge. Various statistical and deep learning methods have attempted to tackle this challenge by leveraging…

Machine Learning · Computer Science 2023-10-09 Ahmed Fakhry , Raneem Khafagy , Adriaan-Alexander Ludl

This study explores the use of graph neural networks (GNNs) with hierarchical pooling and multiple convolution layers for cancer classification based on RNA-seq data. We combine gene expression data from The Cancer Genome Atlas (TCGA) with…

Machine Learning · Computer Science 2026-01-13 Thomas Vaitses Fontanari , Mariana Recamonde-Mendoza

Many complex systems involve interactions between more than two agents. Hypergraphs capture these higher-order interactions through hyperedges that may link more than two nodes. We consider the problem of embedding a hypergraph into…

Social and Information Networks · Computer Science 2023-01-06 Xue Gong , Desmond J. Higham , Konstantinos Zygalakis

Hierarchical graph clustering is a common technique to reveal the multi-scale structure of complex networks. We propose a novel metric for assessing the quality of a hierarchical clustering. This metric reflects the ability to reconstruct…

Social and Information Networks · Computer Science 2018-07-16 Thomas Bonald , Bertrand Charpentier

The main contribution of this article is a new prior distribution over directed acyclic graphs, which gives larger weight to sparse graphs. This distribution is intended for structured Bayesian networks, where the structure is given by an…

Machine Learning · Statistics 2015-04-28 Felix L. Rios , John M. Noble , Timo J. T. Koski

We introduce a family of multilayer graph kernels and establish new links between graph convolutional neural networks and kernel methods. Our approach generalizes convolutional kernel networks to graph-structured data, by representing…

Machine Learning · Statistics 2020-06-30 Dexiong Chen , Laurent Jacob , Julien Mairal

Typical R-convolution graph kernels invoke the kernel functions that decompose graphs into non-isomorphic substructures and compare them. However, overlooking implicit similarities and topological position information between those…

Machine Learning · Computer Science 2024-05-10 Shuhao Tang , Hao Tian , Xiaofeng Cao , Wei Ye

Generative models for graphs have been typically committed to strong prior assumptions concerning the form of the modeled distributions. Moreover, the vast majority of currently available models are either only suitable for characterizing…

Social and Information Networks · Computer Science 2012-10-19 Antonino Freno , Mikaela Keller , Gemma C. Garriga , Marc Tommasi

We introduce an architecture based on deep hierarchical decompositions to learn effective representations of large graphs. Our framework extends classic R-decompositions used in kernel methods, enabling nested part-of-part relations. Unlike…

Machine Learning · Computer Science 2024-03-19 Francesco Orsini , Daniele Baracchi , Paolo Frasconi

The irreducible complexity of natural phenomena has led Graph Neural Networks to be employed as a standard model to perform representation learning tasks on graph-structured data. While their capacity to capture local and global patterns is…

Machine Learning · Computer Science 2024-02-13 Lorenzo Giusti

Graph-based machine learning methods are useful tools in the identification and prediction of variation in genetic data. In particular, the comprehension of phenotypic effects at the cellular level is an accelerating research area in…

Quantitative Methods · Quantitative Biology 2024-12-06 Nandini Gadhia , Michalis Smyrnakis , Po-Yu Liu , Damer Blake , Melanie Hay , Anh Nguyen , Dominic Richards , Dong Xia , Ritesh Krishna

High spectral dimensionality and the shortage of annotations make hyperspectral image (HSI) classification a challenging problem. Recent studies suggest that convolutional neural networks can learn discriminative spatial features, which…

Computer Vision and Pattern Recognition · Computer Science 2018-02-13 Zilong Zhong , Jonathan Li

Stratifying cancer patients based on their gene expression levels allows improving diagnosis, survival analysis and treatment planning. However, such data is extremely highly dimensional as it contains expression values for over 20000 genes…

Graph convolutional network (GCN) based approaches have achieved significant progress for solving complex, graph-structured problems. GCNs incorporate the graph structure information and the node (or edge) features through message passing…

Machine Learning · Computer Science 2021-05-04 Saurav Manchanda , Da Zheng , George Karypis
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