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The understanding of molecular cell biology requires insight into the structure and dynamics of networks that are made up of thousands of interacting molecules of DNA, RNA, proteins, metabolites, and other components. One of the central…

Molecular Networks · Quantitative Biology 2011-02-25 Bhaskar DasGupta , Paola Vera-Licona , Eduardo Sontag

Repeating patterns of spike sequences from a neuronal network have been proposed to be useful in the reconstruction of the network topology. Reverberations in a physiologically realistic model with various physical connection topologies…

Neurons and Cognition · Quantitative Biology 2014-07-15 Hao Song , Chun-Chung Chen , Jyh-Jang Sun , Pik-Yin Lai , C. K. Chan

A biological neural network is constituted by numerous subnetworks and modules with different functionalities. For an artificial neural network, the relationship between a network and its subnetworks is also important and useful for both…

Machine Learning · Computer Science 2016-11-01 Enmei Tu , Guanghao Zhang , Lily Rachmawati , Eshan Rajabally , Guang-Bin Huang

Biomolecular networks have already found great utility in characterizing complex biological systems arising from pair-wise interactions amongst biomolecules. Here, we review how graph theoretical approaches can be applied not only for a…

Molecular Networks · Quantitative Biology 2018-12-03 Heeralal Janwa , Steven E. Massey , Julian Velev , Bud Mishra

Boolean networks have been used in a variety of settings, as models for general complex systems as well as models of specific systems in diverse fields, such as biology, engineering, and computer science. Traditionally, their properties as…

Dynamical Systems · Mathematics 2024-02-02 Matthew Wheeler , Claus Kadelka , Alan Veliz-Cuba , David Murrugarra , Reinhard Laubenbacher

As networks grow in size and complexity, backbones become an essential network representation. Indeed, they provide a simplified yet informative overview of the underlying organization by retaining the most significant and structurally…

Social and Information Networks · Computer Science 2024-07-30 Sanaa Hmaida , Hocine Cherifi , Mohammed El Hassouni

The art of tying knots is exploited in nature and occurs in multiple applications ranging from being an essential part of scouting programs to engineering molecular knots. Biomolecular knots, such as knotted proteins, bear various cellular…

Biological Physics · Physics 2021-06-09 Anatoly Golovnev , Alireza Mashaghi

Despite the large quantity of information available, thorough researches in various biological databases are still needed in order to reconstruct and understand the steps that lead to known or new phenomena. By using protein-protein…

Molecular Networks · Quantitative Biology 2014-12-03 Alberto Calderone

Control problem in a biological system is the problem of finding an interventional policy for changing the state of the biological system from an undesirable state, e.g. disease, into a desirable healthy state. Boolean networks are utilized…

Molecular Networks · Quantitative Biology 2016-09-07 Mohammad Moradi , Sama Goliaei

The ability to compare complex systems can provide new insight into the fundamental nature of the processes captured in ways that are otherwise inaccessible to observation. Here, we introduce the $n$-tangle method to directly compare two…

Physics and Society · Physics 2014-11-27 Lazaros K. Gallos , Nina H. Fefferman

Carbon nanotubes are often seen as the only alternative technology to silicon transistors. While they are the most likely short-term one, other longer-term alternatives should be studied as well. While contemplating biological neurons as an…

Neurons and Cognition · Quantitative Biology 2007-05-23 Hugues Berry , Olivier Temam

Modeling biological networks serves as both a major goal and an effective tool of systems biology in studying mechanisms that orchestrate the activities of gene products in cells. Biological networks are context specific and dynamic in…

Molecular Networks · Quantitative Biology 2014-02-20 Ye Tian , Bai Zhang , Eric P. Hoffman , Robert Clarke , Zhen Zhang , Ie-Ming Shih , Jianhua Xuan , David M. Herrington , Yue Wang

Tree tensor network (TTN) provides an essential theoretical framework for the practical simulation of quantum many-body systems, where the network structure defined by the connectivity of the isometry tensors plays a crucial role in…

Statistical Mechanics · Physics 2023-01-24 Toshiya Hikihara , Hiroshi Ueda , Kouichi Okunishi , Kenji Harada , Tomotoshi Nishino

In the study of networked systems such as biological, technological, and social networks the available data are often uncertain. Rather than knowing the structure of a network exactly, we know the connections between nodes only with a…

Social and Information Networks · Computer Science 2016-01-20 Travis Martin , Brian Ball , M. E. J. Newman

We propose and study a set of algorithms for discovering community structure in networks -- natural divisions of network nodes into densely connected subgroups. Our algorithms all share two definitive features: first, they involve iterative…

Statistical Mechanics · Physics 2009-11-10 M. E. J. Newman , M. Girvan

Discrete dynamic models are a powerful tool for the understanding and modeling of large biological networks. Although a lot of progress has been made in developing analysis tools for these models, there is still a need to find approaches…

Molecular Networks · Quantitative Biology 2013-06-14 Jorge G. T. Zañudo , Réka Albert

We consider in this paper the problem of discovering, via a traceroute algorithm, the topology of a network, whose graph is spanned by an infinite branching process. A subset of nodes is selected according to some criterion. As a measure of…

Networking and Internet Architecture · Computer Science 2009-08-25 Fabrice Guillemin , Philippe Robert

Estimating influential nodes in large scale networks including but not limited to social networks, biological networks, communication networks, emerging smart grids etc. is a topic of fundamental interest. To understand influences of nodes…

Social and Information Networks · Computer Science 2014-06-13 Sima Das

In a recurrent setting, conventional approaches to neural architecture search find and fix a general model for all data samples and time steps. We propose a novel algorithm that can dynamically search for the structure of cells in a…

Machine Learning · Computer Science 2019-05-28 Xin Qian , Matthew Kennedy , Diego Klabjan

Interconnected ensembles of biological entities are perhaps some of the most complex systems that modern science has encountered so far. In particular, scientists have concentrated on understanding how the complexity of the interacting…

Pattern Formation and Solitons · Physics 2020-11-18 Bram A. Siebert , Cameron L. Hall , James P. Gleeson , Malbor Asllani