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A population quantity of interest in statistical shape analysis is the location of landmarks, which are points that aid in reconstructing and representing shapes of objects. We provide an automated, model-based approach to inferring…
Purpose: Semantic segmentation and landmark detection are fundamental tasks of medical image processing, facilitating further analysis of anatomical objects. Although deep learning-based pixel-wise classification has set a…
In this paper, we propose a novel deep learning framework for anatomy segmentation and automatic landmark- ing. Specifically, we focus on the challenging problem of mandible segmentation from cone-beam computed tomography (CBCT) scans and…
Stochastic differential equations (SDEs) are a ubiquitous modeling framework that finds applications in physics, biology, engineering, social science, and finance. Due to the availability of large-scale data sets, there is growing interest…
Deep learning techniques for anatomical landmark localization (ALL) have shown great success, but their reliance on large annotated datasets remains a problem due to the tedious and costly nature of medical data acquisition and annotation.…
Dynamic mode decomposition (DMD) is a widely used data-driven algorithm for predicting the future states of dynamical systems. However, its standard formulation often struggles with poor long-term predictive accuracy. To address this…
As an important upstream task for many medical applications, supervised landmark localization still requires non-negligible annotation costs to achieve desirable performance. Besides, due to cumbersome collection procedures, the limited…
Estimation of Markov Random Field and covariance models from high-dimensional data represents a canonical problem that has received a lot of attention in the literature. A key assumption, widely employed, is that of {\em sparsity} of the…
We propose a new method to obtain landmark-matching transformations between n-dimensional Euclidean spaces with large deformations. Given a set of feature correspondences, our algorithm searches for an optimal folding-free mapping that…
The differences in brain dynamics across human subjects, commonly referred to as human artifacts, have long been a challenge in the field, severely limiting the generalizability of brain dynamics recognition models. Traditional methods for…
We study the effect of noise on the evolution of the growth factor of density perturbations in the context of the LCDM model. Stochasticity is introduced as a Wiener process amplified by an intensity parameter alpha. By comparing the…
Many consequential real-world systems, like wind fields and ocean currents, are dynamic and hard to model. Learning their governing dynamics remains a central challenge in scientific machine learning. Dynamic Mode Decomposition (DMD)…
Temporal volume images with 3D+t (4D) information are often used in medical imaging to statistically analyze temporal dynamics or capture disease progression. Although deep-learning-based generative models for natural images have been…
In this work, we derive a model for the covariance of the visual residuals in multi-view SfM, odometry and SLAM setups. The core of our approach is the formulation of the residual covariances as a combination of geometric and photometric…
Markerless biomechanics increasingly relies on 3D skeletal keypoints extracted from video, yet downstream biomechanical mappings typically treat these estimates as deterministic, providing no principled mechanism for frame-wise quality…
Volumetric ultrasound has great potentials in promoting prenatal examinations. Automated solutions are highly desired to efficiently and effectively analyze the massive volumes. Segmentation and landmark localization are two key techniques…
We propose a deformable registration algorithm based on unsupervised learning of a low-dimensional probabilistic parameterization of deformations. We model registration in a probabilistic and generative fashion, by applying a conditional…
I propose a novel framework that integrates stochastic differential equations (SDEs) with deep generative models to improve uncertainty quantification in machine learning applications involving structured and temporal data. This approach,…
Statistical shape modeling is an important tool to characterize variation in anatomical morphology. Typical shapes of interest are measured using 3D imaging and a subsequent pipeline of registration, segmentation, and some extraction of…
Predicting the spatio-temporal progression of brain tumors is essential for guiding clinical decisions in neuro-oncology. We propose a hybrid mechanistic learning framework that combines a mathematical tumor growth model with a guided…