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Modern high-dimensional point process data, especially those from neuroscience experiments, often involve observations from multiple conditions and/or experiments. Networks of interactions corresponding to these conditions are expected to…

Methodology · Statistics 2021-09-27 Xu Wang , Ali Shojaie

The experimental study of neural networks requires simultaneous measurements of a massive number of neurons, while monitoring properties of the connectivity, synaptic strengths and delays. Current technological barriers make such a mission…

Neurons and Cognition · Quantitative Biology 2016-01-12 Amir Goldental , Pinhas Sabo , Shira Sardi , Roni Vardi , Ido Kanter

Simultaneous recordings from many neurons hide important information and the connections characterizing the network remain generally undiscovered despite the progresses of statistical and machine learning techniques. Discerning the presence…

Applications · Statistics 2019-03-21 Pietro Verzelli , Laura Sacerdote

We present two Bayesian procedures to infer the interactions and external currents in an assembly of stochastic integrate-and-fire neurons from the recording of their spiking activity. The first procedure is based on the exact calculation…

Machine Learning · Statistics 2011-02-28 Remi Monasson , Simona Cocco

Understanding the dynamics of neural networks is a major challenge in experimental neuroscience. For that purpose, a modelling of the recorded activity that reproduces the main statistics of the data is required. In a first part, we present…

Neurons and Cognition · Quantitative Biology 2014-04-15 Hassan Nasser , Olivier Marre , Bruno Cessac

The relative timing of action potentials in neurons recorded from local cortical networks often shows a non-trivial dependence, which is then quantified by cross-correlation functions. Theoretical models emphasize that such spike train…

Neurons and Cognition · Quantitative Biology 2017-06-28 Taskin Deniz , Stefan Rotter

Background: Current neuronal monitoring techniques, such as calcium imaging and multi-electrode arrays, enable recordings of spiking activity from hundreds of neurons simultaneously. Of primary importance in systems neuroscience is the…

Neurons and Cognition · Quantitative Biology 2014-11-11 Yazan N. Billeh , Michael T. Schaub , Costas A. Anastassiou , Mauricio Barahona , Christof Koch

Simultaneous behavioral and electrophysiological recordings call for new methods to reveal the interactions between neural activity and behavior. A milestone would be an interpretable model of the co-variability of spiking activity and…

Neurons and Cognition · Quantitative Biology 2023-12-04 Christos Sourmpis , Carl Petersen , Wulfram Gerstner , Guillaume Bellec

Observations of finely-timed spike relationships in population recordings have been used to support partial reconstruction of neural microcircuit diagrams. In this approach, fine-timescale components of paired spike train interactions are…

Neurons and Cognition · Quantitative Biology 2021-02-15 Jonathan Platkiewicz , Zachary Saccomano , Sam McKenzie , Daniel English , Asohan Amarasingham

Multi-electrode arrays (MEAs) can record extracellular action potentials (also known as 'spikes') from hundreds or thousands of neurons simultaneously. Inference of a functional network from a spike train is a fundamental and formidable…

Computational Engineering, Finance, and Science · Computer Science 2020-07-07 Yun Zhao , Richard Jiang , Zhenni Xu , Elmer Guzman , Paul K. Hansma , Linda Petzold

Recent experimental advances are producing an avalanche of data on both neural connectivity and neural activity. To take full advantage of these two emerging datasets we need a framework that links them, revealing how collective neural…

Neurons and Cognition · Quantitative Biology 2020-02-27 Gabriel Koch Ocker , Krešimir Josić , Eric Shea-Brown , Michael A. Buice

We address the problem of finding patterns from multi-neuronal spike trains that give us insights into the multi-neuronal codes used in the brain and help us design better brain computer interfaces. We focus on the synchronous firings of…

Neural and Evolutionary Computing · Computer Science 2010-06-09 Raajay Viswanathan , P. S. Sastry , K. P. Unnikrishnan

This paper models the dynamics of a large set of interacting neurons within the framework of statistical field theory. We use a method initially developed in the context of statistical field theory [44] and later adapted to complex systems…

Neurons and Cognition · Quantitative Biology 2022-05-25 Pierre Gosselin , Aïleen Lotz , Marc Wambst

Extracellular recordings with multi-electrode arrays is one of the basic tools of contemporary neuroscience. These recordings are mostly used to monitor the activities, understood as sequences of emitted action potentials, of many…

Computational Engineering, Finance, and Science · Computer Science 2014-12-22 Christophe Pouzat , Georgios Is. Detorakis

Identifying stimulus-driven neural activity patterns is critical for studying the neural basis of cognition. This can be particularly challenging in intracranial datasets, where electrode locations typically vary across patients. This…

Neurons and Cognition · Quantitative Biology 2022-02-07 Jeremy R. Manning

Multielectrode arrays allow recording of the activity of many single neurons, from which correlations can be calculated. The functional roles of correlations can be revealed by the measures of the information conveyed by neuronal activity;…

Statistical Mechanics · Physics 2009-09-25 Michele Bezzi , Mathew E. Diamond , Alessandro Treves

Extracting the spectral representations of the neural processes that underlie spiking activity is key to understanding how the brain rhythms mediate cognitive functions. While spectral estimation of continuous time-series is well studied,…

Information Theory · Computer Science 2020-12-02 Anuththara Rupasinghe , Behtash Babadi

An essential step toward understanding neural circuits is linking their structure and their dynamics. In general, this relationship can be almost arbitrarily complex. Recent theoretical work has, however, begun to identify some broad…

Neurons and Cognition · Quantitative Biology 2017-03-10 Gabriel Koch Ocker , Yu Hu , Michael A. Buice , Brent Doiron , Krešimir Josić , Robert Rosenbaum , Eric Shea-Brown

Human brain neuron activities are incredibly significant nowadays. Neuronal behavior is assessed by analyzing signal data such as electroencephalography (EEG), which can offer scientists valuable information about diseases and…

The models in statistical physics such as an Ising model offer a convenient way to characterize stationary activity of neural populations. Such stationary activity of neurons may be expected for recordings from in vitro slices or…

Neurons and Cognition · Quantitative Biology 2017-05-05 Christian Donner , Klaus Obermayer , Hideaki Shimazaki