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We consider a single genetic locus with two alleles $A_1$ and $A_2$ in a large haploid population. The locus is subject to selection and two-way, or recurrent, mutation. Assuming the allele frequencies follow a Wright-Fisher diffusion and…

Probability · Mathematics 2024-04-29 Wai-Tong Louis Fan , John Wakeley

A simple weakly frequency dependent model for the dynamics of a population with a finite number of types is proposed, based upon an advantage of being rare. In the infinite population limit, this model gives rise to a non-smooth dynamical…

Populations and Evolution · Quantitative Biology 2007-05-23 Michael Baake , Uwe Grimm , Harald Jockusch

Traditionally, population models distinguish individuals on the basis of their current state. Given a distribution, a discrete time model then specifies (precisely in deterministic models, probabilistically in stochastic models) the…

Populations and Evolution · Quantitative Biology 2023-09-21 B. Boldin , O. Diekmann , J. A. J. Metz

We study ancestral structures for the two-type Moran model with mutation and frequency-dependent selection under the nonlinear dominance or fittest-type-wins scheme. Under appropriate conditions, both lead, in distribution, to the same…

Probability · Mathematics 2024-07-12 Ellen Baake , Luigi Esercito , Sebastian Hummel

Genetic diversity is central to the process of evolution. Both natural selection and random genetic drift are influenced by the level of genetic diversity of a population; selection acts on diversity while drift samples from it. At a given…

Populations and Evolution · Quantitative Biology 2024-11-12 Nikolas Vellnow , Toni I. Gossmann , David Waxman

The Wright-Fisher model describes a biological population containing a finite number of individuals. In this work we consider a Wright-Fisher model for a randomly mating population, where selection and mutation act at an unlinked locus. The…

Populations and Evolution · Quantitative Biology 2024-07-18 David Waxman

We are interested in modeling Darwinian evolution resulting from the interplay of phenotypic variation and natural selection through ecological interactions. The population is modeled as a stochastic point process whose generator captures…

Probability · Mathematics 2011-02-01 Benjamin Jourdain , Sylvie Méléard , Wojbor Woyczynski

The purpose of this Note is twofold: First, we introduce the general formalism of evolutionary genetics dynamics involving fitnesses, under both the deterministic and stochastic setups, and chiefly in discrete-time. In the process, we…

Quantitative Methods · Quantitative Biology 2015-05-14 Thierry Huillet

Diffusion theory is a central tool of modern population genetics, yielding simple expressions for fixation probabilities and other quantities that are not easily derived from the underlying Wright-Fisher model. Unfortunately, the textbook…

Populations and Evolution · Quantitative Biology 2022-12-19 Camila Bräutigam , Matteo Smerlak

We are interested in the dynamics of a population structured by a phenotypic trait. Individuals reproduce sexually, which is represented by a non-linear integral operator. This operator is combined to a multiplicative operator representing…

Analysis of PDEs · Mathematics 2021-04-14 Gaël Raoul

Populations are made up of an integer number of individuals and are subject to stochastic birth-death processes whose rates may vary in time. Useful quantities, like the chance of ultimate fixation, satisfy an appropriate difference…

Populations and Evolution · Quantitative Biology 2020-07-22 Jayant Pande , Nadav M. Shnerb

Biological evolution depends on the passing down to subsequent generations of genetic information encoding beneficial traits, and on the removal of unfit individuals by a selection mechanism. However, selection acts on phenotypes, and is…

Populations and Evolution · Quantitative Biology 2026-05-01 Bastien Mallein , Francesco Paparella , Emmanuel Schertzer , Zsófia Talyigás

We establish a genealogical framework for an existing analytical moment duality between a Wright--Fisher type SDE and a counting process with interaction. To achieve this, we construct a finite-population Moran model featuring interactive…

Probability · Mathematics 2026-05-05 Ellen Baake , Fernando Cordero , Hannah Dopmeyer

We study fixation probabilities and times as a consequence of neutral genetic drift in subdivided populations, motivated by a model of the cultural evolutionary process of language change that is described by the same mathematics as the…

Populations and Evolution · Quantitative Biology 2015-05-26 R A Blythe

We propose an extension of the classical $\Lambda$-Fleming-Viot model to intrinsically varying population sizes. During events, instead of replacing a proportion of the population, a random mass dies and a, possibly different, random mass…

Probability · Mathematics 2023-11-13 Julian Kern , Bastian Wiederhold

When a population inhabits an inhomogeneous environment, the fitness value of traits can vary with the position in the environment. Gene flow caused by random mating can nevertheless prevent that a sexually reproducing population splits…

Populations and Evolution · Quantitative Biology 2011-05-05 Susanne Schindler , Olaf Breidbach , Juergen Jost

Frequency dependent selection and demographic fluctuations play important roles in evolutionary and ecological processes. Under frequency dependent selection, the average fitness of the population may increase or decrease based on…

Populations and Evolution · Quantitative Biology 2015-06-23 Weini Huang , Christoph Hauert , Arne Traulsen

Darwinian evolution can be modeled in general terms as a flow in the space of fitness (i.e. reproductive rate) distributions. In the diffusion approximation, Tsimring et al. have showed that this flow admits "fitness wave" solutions:…

Populations and Evolution · Quantitative Biology 2017-01-30 Matteo Smerlak , Ahmed Youssef

We study the evolution of gene frequencies in a population living in $\mathbb{R}^d$, modelled by the spatial Lambda Fleming-Viot process with natural selection (Barton, Etheridge and Veber, 2010 and Etheridge, Veber and Yu, 2014). We…

Probability · Mathematics 2022-10-04 Raphaël Forien , Sarah Penington

We examine the distributional properties of a Feller diffusion $(X(\tau))_{\tau \in [0, t]}$ conditioned on the current population $X(t)$ having a single ancestor at time zero. The approach is novel and is based on an interpretation of…

Probability · Mathematics 2025-09-24 Conrad J. Burden , Robert C. Griffiths
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