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We propose a permutation-based method for testing a large collection of hypotheses simultaneously. Our method provides lower bounds for the number of true discoveries in any selected subset of hypotheses. These bounds are simultaneously…

Applications · Statistics 2023-01-30 Angela Andreella , Jesse Hemerik , Wouter Weeda , Livio Finos , Jelle Goeman

Large vision-language models (VLMs) often rely on familiar semantic priors, but existing evaluations do not cleanly separate perception failures from rule-mapping failures. We study this behavior as semantic fixation: preserving a default…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Md Tanvirul Alam

Clinical decision-making relies on the integrated analysis of medical images and the associated clinical reports. While Vision-Language Models (VLMs) can offer a unified framework for such tasks, they can exhibit strong biases toward one…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 David Restrepo , Ira Ktena , Maria Vakalopoulou , Stergios Christodoulidis , Enzo Ferrante

Vision-language model (VLM) embeddings have been shown to encode biases present in their training data, such as societal biases that prescribe negative characteristics to members of various racial and gender identities. VLMs are being…

Computer Vision and Pattern Recognition · Computer Science 2024-11-08 Walter Gerych , Haoran Zhang , Kimia Hamidieh , Eileen Pan , Maanas Sharma , Thomas Hartvigsen , Marzyeh Ghassemi

Neural demyelination and brain damage accumulated in white matter appear as hyperintense areas on T2-weighted MRI scans in the form of lesions. Modeling binary images at the population level, where each voxel represents the existence of a…

Methodology · Statistics 2023-05-29 Anna Menacher , Thomas E. Nichols , Chris Holmes , Habib Ganjgahi

Vision-language models (VLMs) are gaining attention in medical image analysis. These are pre-trained on large, heterogeneous data sources, yielding rich and transferable representations. Notably, the combination of modality-specialized VLMs…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Julio Silva-Rodríguez , Fereshteh Shakeri , Houda Bahig , Jose Dolz , Ismail Ben Ayed

Multiple hypothesis testing is a significant problem in nearly all neuroimaging studies. In order to correct for this phenomena, we require a reliable estimate of the Family-Wise Error Rate (FWER). The well known Bonferroni correction…

Computation · Statistics 2015-02-17 Chris Hinrichs , Vamsi K Ithapu , Qinyuan Sun , Sterling C Johnson , Vikas Singh

Functional connectivity (FC) analysis of resting-state fMRI data provides a framework for characterizing brain networks and their association with participant-level covariates. Due to the high dimensionality of neuroimaging data, standard…

Methodology · Statistics 2025-08-18 Wei Zhao , Brian J. Reich , Emily C. Hector

The dramatically growing availability of observational data is being witnessed in various domains of science and technology, which facilitates the study of causal inference. However, estimating treatment effects from observational data is…

Machine Learning · Statistics 2021-06-08 Zhixuan Chu , Stephen L. Rathbun , Sheng Li

Causal mapping of the functional organisation of the human brain requires evidence of \textit{necessity} available at adequate scale only from pathological lesions of natural origin. This demands inferential models with sufficient…

Machine Learning · Computer Science 2023-05-30 Guilherme Pombo , Robert Gray , Amy P. K. Nelson , Chris Foulon , John Ashburner , Parashkev Nachev

In this paper, we consider voxel selection for functional Magnetic Resonance Imaging (fMRI) brain data with the aim of finding a more complete set of probably correlated discriminative voxels, thus improving interpretation of the discovered…

Computer Vision and Pattern Recognition · Computer Science 2015-06-09 Yilun Wang , Junjie Zheng , Sheng Zhang , Xujun Duan , Huafu Chen

Learning-based multi-view stereo (MVS) methods have made impressive progress and surpassed traditional methods in recent years. However, their accuracy and completeness are still struggling. In this paper, we propose a new method to enhance…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Yikang Ding , Zhenyang Li , Dihe Huang , Zhiheng Li , Kai Zhang

Voxel-based Morphometry (VBM) has emerged as a powerful approach in neuroimaging research, utilized in over 7,000 studies since the year 2000. Using Magnetic Resonance Imaging (MRI) data, VBM assesses variations in the local density of…

In text-to-image person retrieval tasks, the diversity of natural language expressions and the implicitness of visual semantics often lead to the problem of Expression Drift, where semantically equivalent texts exhibit significant feature…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Chao Yuan , Yujian Zhao , Haoxuan Xu , Guanglin Niu

Accurate biomedical image classification under low-resource conditions remains challenging due to limited annotations, subtle inter-class visual differences, and complex disease semantics. While vision--language models offer a promising…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Xiaoliu Luo , Minxue Xiao , Ting Xie , Mengzhu Wang , Huiqing Qi , Joey Tianyi Zhou , Taiping Zhang , Xu Wang

Medical image diagnosis is challenging because many diseases resemble normal anatomy and exhibit substantial interpatient variability. Clinicians routinely rely on comparative diagnosis, such as referencing cross-patient healthy control…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Ruinan Jin , Gexin Huang , Xinwei Shen , Qiong Zhang , Yan Shuo Tan , Xiaoxiao Li

Neurodegenerative diseases are frequently associated with structural changes in the brain. Magnetic Resonance Imaging (MRI) scans can show these variations and therefore be used as a supportive feature for a number of neurodegenerative…

The deformation of the lateral ventricle (LV) shape is widely studied to identify specific morphometric changes associated with diseases. Since LV enlargement is considered a relative change due to brain atrophy, local longitudinal LV…

Image and Video Processing · Electrical Eng. & Systems 2024-10-10 Wonjung Park , Suhyun Ahn , Jinah Park

Support vector machine (SVM) is one of the most popular classification algorithms in the machine learning literature. We demonstrate that SVM can be used to balance covariates and estimate average causal effects under the unconfoundedness…

Methodology · Statistics 2021-07-02 Alexander Tarr , Kosuke Imai

Latent variable models (LVMs) are commonly used in psychology and increasingly used for analyzing brain imaging data. Such studies typically involve a small number of participants (n<100), where standard asymptotic results often fail to…

Methodology · Statistics 2020-06-15 Brice Ozenne , Patrick M. Fisher , Esben Budtz-Jørgensen