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Existing medical RAG systems mainly leverage knowledge from medical knowledge bases, neglecting the crucial role of experiential knowledge derived from similar patient cases -- a key component of human clinical reasoning. To bridge this…

Computation and Language · Computer Science 2025-05-27 Yuxing Lu , Gecheng Fu , Wei Wu , Xukai Zhao , Sin Yee Goi , Jinzhuo Wang

Electronic health record (EHR) systems present clinicians with vast repositories of clinical information, creating a significant cognitive burden where critical details are easily overlooked. While Large Language Models (LLMs) offer…

Computation and Language · Computer Science 2026-03-17 Samuel Thio , Matthew Lewis , Spiros Denaxas , Richard JB Dobson

The mining of adverse drug events (ADEs) is pivotal in pharmacovigilance, enhancing patient safety by identifying potential risks associated with medications, facilitating early detection of adverse events, and guiding regulatory…

Artificial Intelligence · Computer Science 2024-10-04 Pranab Sahoo , Ayush Kumar Singh , Sriparna Saha , Aman Chadha , Samrat Mondal

Ensuring truthfulness in large language models (LLMs) remains a critical challenge for reliable text generation. While supervised fine-tuning and reinforcement learning with human feedback have shown promise, they require a substantial…

Machine Learning · Computer Science 2026-03-17 Manh Nguyen , Sunil Gupta , Hung Le

Doctors typically write in incomprehensible handwriting, making it difficult for both the general public and some pharmacists to understand the medications they have prescribed. It is not ideal for them to write the prescription quietly and…

Computer Vision and Pattern Recognition · Computer Science 2022-10-24 Pavithiran G , Sharan Padmanabhan , Nuvvuru Divya , Aswathy V , Irene Jerusha P , Chandar B

Accurate medical coding requires consulting authoritative resources such as the ICD tabular list and coding guidelines. Existing LLM-based automated methods largely rely on LLMs' internal knowledge, which is prone to hallucination and…

Computation and Language · Computer Science 2026-05-29 Yidong Gan , David D. Nguyen , Yang Lin , Peter Zhong , Thanh Vu , Long Duong , Yuan-Fang Li

Generating long and semantic-coherent reports to describe medical images poses great challenges towards bridging visual and linguistic modalities, incorporating medical domain knowledge, and generating realistic and accurate descriptions.…

Computer Vision and Pattern Recognition · Computer Science 2019-03-26 Christy Y. Li , Xiaodan Liang , Zhiting Hu , Eric P. Xing

AI Scientists have shown promising progress across multiple stages of the research pipeline, among which automatic scientific paper writing remains a formidable challenge. The Introduction writing is especially challenging, which demands…

Artificial Intelligence · Computer Science 2026-05-26 Jiabei Xiao , Yizhou Wang , Chen Tang , Pengze Li , Wanli Ouyang , Shixiang Tang

We introduce a novel graph-based Retrieval-Augmented Generation (RAG) framework specifically designed for the medical domain, called \textbf{MedGraphRAG}, aimed at enhancing Large Language Model (LLM) capabilities for generating…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Junde Wu , Jiayuan Zhu , Yunli Qi , Jingkun Chen , Min Xu , Filippo Menolascina , Vicente Grau

The deployment of Large Language Models (LLMs) for structuring clinical data is critically hindered by their tendency to hallucinate facts and their inability to follow domain-specific rules. To address this, we introduce MedPAO, a novel…

Multimodal agents offer a promising path to automating complex document-intensive workflows. Yet, a critical question remains: do these agents demonstrate genuine strategic reasoning, or merely stochastic trial-and-error search? To address…

Medical document OCR is challenging due to complex layouts, domain-specific terminology, and noisy annotations, while requiring strict field-level exact matching. Existing OCR systems and general-purpose vision-language models often fail to…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Wenjie Wang , Wei Wu , Ying Liu , Yuan Zhao , Xiaole Lv , Liang Diao , Zengjian Fan , Wenfeng Xie , Ziling Lin , De Shi , Lin Huang , Kaihe Xu , Hong Li

How can we interpret and retrieve medical evidence to support clinical decisions? Clinical trial reports (CTR) amassed over the years contain indispensable information for the development of personalized medicine. However, it is practically…

Computation and Language · Computer Science 2023-10-31 Maël Jullien , Marco Valentino , Hannah Frost , Paul O'Regan , Donal Landers , André Freitas

The advancement of natural language processing (NLP) has been significantly boosted by the development of transformer-based large language models (LLMs). These models have revolutionized NLP tasks, particularly in code generation, aiding…

Computation and Language · Computer Science 2024-05-27 Dong Huang , Jie M. Zhang , Michael Luck , Qingwen Bu , Yuhao Qing , Heming Cui

Generating radiology reports is time-consuming and requires extensive expertise in practice. Therefore, reliable automatic radiology report generation is highly desired to alleviate the workload. Although deep learning techniques have been…

Image and Video Processing · Electrical Eng. & Systems 2019-07-24 Jianbo Yuan , Haofu Liao , Rui Luo , Jiebo Luo

Adverse drug events (ADEs) are unexpected incidents caused by the administration of a drug or medication. To identify and extract these events, we require information about not just the drug itself but attributes describing the drug (e.g.,…

Computation and Language · Computer Science 2021-04-23 Darshini Mahendran , Bridget T. McInnes

Social media has grown to be a crucial information source for pharmacovigilance studies where an increasing number of people post adverse reactions to medical drugs that are previously unreported. Aiming to effectively monitor various…

Machine Learning · Computer Science 2018-02-19 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu

We propose a natural language prompt-based retrieval augmented generation (Prompt-RAG), a novel approach to enhance the performance of generative large language models (LLMs) in niche domains. Conventional RAG methods mostly require vector…

Computation and Language · Computer Science 2024-01-23 Bongsu Kang , Jundong Kim , Tae-Rim Yun , Chang-Eop Kim

Question answering over visually rich documents (VRDs) requires reasoning not only over isolated content but also over documents' structural organization and cross-page dependencies. However, conventional retrieval-augmented generation…

Computation and Language · Computer Science 2026-03-03 Zhivar Sourati , Zheng Wang , Marianne Menglin Liu , Yazhe Hu , Mengqing Guo , Sujeeth Bharadwaj , Kyu Han , Tao Sheng , Sujith Ravi , Morteza Dehghani , Dan Roth

Adverse drug reactions (ADRs) are a major barrier to safe and effective pharmacotherapy and increasingly reflect higher order interactions between drugs, genetic background, and clinical phenotypes. Existing graph based approaches usually…

Quantitative Methods · Quantitative Biology 2025-12-02 Ze Cai , Haotian Tang , Shuai Gao , Binbin Zhou , Junhan Zhao , Jun Wen