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Background: Psychedelic drugs facilitate profound changes in consciousness and have potential to provide insights into the nature of human mental processes and their relation to brain physiology. Yet published scientific literature reflects…

Quantitative Methods · Quantitative Biology 2012-06-05 Jeremy R. Coyle , David E. Presti , Matthew J. Baggott

Biomedical research papers use significantly different language and jargon when compared to typical English text, which reduces the utility of pre-trained NLP models in this domain. Meanwhile Medline, a database of biomedical abstracts,…

Machine Learning · Computer Science 2021-09-15 Justin Sybrandt , Ilya Safro

Automatic Medical Imaging Narrative generation aims to alleviate the workload of radiologists by producing accurate clinical descriptions directly from radiological images. However, the subtle visual nuances and domain-specific terminology…

Computer Vision and Pattern Recognition · Computer Science 2024-09-09 Kai Shu , Yuzhuo Jia , Ziyang Zhang , Jiechao Gao

Molecular optimization is a central task in drug discovery that requires precise structural reasoning and domain knowledge. While large language models (LLMs) have shown promise in generating high-level editing intentions in natural…

Machine Learning · Computer Science 2025-10-17 Wenyu Zhu , Chengzhu Li , Xiaohe Tian , Yifan Wang , Yinjun Jia , Jianhui Wang , Bowen Gao , Ya-Qin Zhang , Wei-Ying Ma , Yanyan Lan

Revealing Adverse Drug Reactions (ADR) is an essential part of post-marketing drug surveillance, and data from health-related forums and medical communities can be of a great significance for estimating such effects. In this paper, we…

Information Retrieval · Computer Science 2017-06-20 Liliya Akhtyamova , Andrey Ignatov , John Cardiff

Computational biology offers immense potential for reducing the high costs and protracted cycles of new drug development through adverse drug reaction (ADR) prediction. However, current methods remain impeded by drug data scarcity-induced…

Machine Learning · Computer Science 2026-01-06 Yuyan Pi , Min Jin , Wentao Xie , Xinhua Liu

Code generation aims to produce code that fulfills requirements written in natural languages automatically. Large language Models (LLMs) like ChatGPT have demonstrated promising effectiveness in this area. Nonetheless, these LLMs often fail…

Software Engineering · Computer Science 2025-01-15 Ruwei Pan , Hongyu Zhang , Chao Liu

Systematic literature reviews are essential for synthesizing scientific evidence but are costly, difficult to scale and time-intensive, creating bottlenecks for evidence-based policy. We study whether large language models can automate the…

The learning process for medical residents presents significant challenges, demanding both the ability to interpret complex case reports and the rapid acquisition of accurate medical knowledge from reliable sources. Residents typically…

Computation and Language · Computer Science 2026-02-03 Dongsuk Jang , Ziyao Shangguan , Kyle Tegtmeyer , Anurag Gupta , Jan Czerminski , Sophie Chheang , Arman Cohan

Neural audio codecs have made significant strides in efficiently mapping raw audio waveforms into discrete token representations, which are foundational for contemporary audio generative models. However, most existing codecs are optimized…

The automation of chemical research through self-driving laboratories (SDLs) promises to accelerate scientific discovery, yet the reliability and granular performance of the underlying AI agents remain critical, under-examined challenges.…

Artificial Intelligence · Computer Science 2025-10-01 Gihan Panapitiya , Emily Saldanha , Heather Job , Olivia Hess

With advances in generative artificial intelligence (AI), it is now possible to produce realistic-looking automated reports for preliminary reads of radiology images. This can expedite clinical workflows, improve accuracy and reduce overall…

Artificial Intelligence · Computer Science 2025-06-03 Razi Mahmood , Diego Machado Reyes , Ge Wang , Mannudeep Kalra , Pingkun Yan

Code synthesis, which requires a deep understanding of complex natural language problem descriptions, generation of code instructions for complex algorithms and data structures, and the successful execution of comprehensive unit tests,…

Computation and Language · Computer Science 2024-05-21 Md. Ashraful Islam , Mohammed Eunus Ali , Md Rizwan Parvez

Code generation has attracted increasing attention with the rise of Large Language Models (LLMs). Many studies have developed powerful code LLMs by synthesizing code-related instruction data and applying supervised fine-tuning. However,…

Computation and Language · Computer Science 2025-08-22 Changzhi Zhou , Xinyu Zhang , Dandan Song , Xiancai Chen , Wanli Gu , Huipeng Ma , Yuhang Tian , Mengdi Zhang , Linmei Hu

Retrieval approaches that score documents based on learned dense vectors (i.e., dense retrieval) rather than lexical signals (i.e., conventional retrieval) are increasingly popular. Their ability to identify related documents that do not…

Information Retrieval · Computer Science 2023-08-01 Hrishikesh Kulkarni , Sean MacAvaney , Nazli Goharian , Ophir Frieder

In the realm of medical report generation (MRG), the integration of natural language processing has emerged as a vital tool to alleviate the workload of radiologists. Despite the impressive capabilities demonstrated by large vision language…

Computation and Language · Computer Science 2026-01-23 Ruoqing Zhao , Runze Xia , Piji Li

Laboratory testing and medication prescription are two of the most important routines in daily clinical practice. Developing an artificial intelligence system that can automatically make lab test imputations and medication recommendations…

Machine Learning · Computer Science 2022-02-07 Chengsheng Mao , Liang Yao , Yuan Luo

Drug discovery is a long, expensive, and complex process, relying heavily on human medicinal chemists, who can spend years searching the vast space of potential therapies. Recent advances in artificial intelligence for chemistry have sought…

Computation and Language · Computer Science 2025-10-14 Reza Averly , Frazier N. Baker , Ian A. Watson , Xia Ning

Timely and accurate extraction of Adverse Drug Events (ADE) from biomedical literature is paramount for public safety, but involves slow and costly manual labor. We set out to improve drug safety monitoring (pharmacovigilance, PV) through…

Objectives: To advance state-of-the-art for duplicate detection in large-scale pharmacovigilance databases and achieve more consistent performance across adverse event reports from different countries. Background: Unlinked adverse event…

Artificial Intelligence · Computer Science 2026-01-23 Jim W. Barrett , Nils Erlanson , Joana Félix China , G. Niklas Norén
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