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Large language models (LLMs) have shown promise in medical question answering but often struggle with hallucinations and shallow reasoning, particularly in tasks requiring nuanced clinical understanding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2025-08-25 Ziyu Wang , Elahe Khatibi , Amir M. Rahmani

Reproducibility of research is essential for science. However, in the way modern computational biology research is done, it is easy to lose track of small, but extremely critical, details. Key details, such as the specific version of a…

In today's legal environment, lawsuits and regulatory investigations require companies to embark upon increasingly intensive data-focused engagements to identify, collect and analyze large quantities of data. When documents are staged for…

Information Retrieval · Computer Science 2019-04-04 Rishi Chhatwal , Peter Gronvall , Nathaniel Huber-Fliflet , Robert Keeling , Jianping Zhang , Haozhen Zhao

Repurposing approved drugs offers a time-efficient and cost-effective alternative to traditional drug development. However, in silico prediction of repurposing candidates is challenging and requires the effective collaboration of…

Artificial Intelligence · Computer Science 2026-02-10 Simon Süwer , Kester Bagemihl , Sylvie Baier , Lucia Dicunta , Markus List , Jan Baumbach , Andreas Maier , Fernando M. Delgado-Chaves

Diagnosing hepatic diseases accurately and interpretably is critical, yet it remains challenging in real-world clinical settings. Existing AI approaches for clinical diagnosis often lack transparency, structured reasoning, and…

Artificial Intelligence · Computer Science 2026-03-06 Zheng Li , Jiayi Xu , Zhikai Hu , Hechang Chen , Lele Cong , Yunyun Wang , Shuchao Pang

The selection of appropriate medical imaging procedures is a critical and complex clinical decision, guided by extensive evidence-based standards such as the ACR Appropriateness Criteria (ACR-AC). However, the underutilization of these…

Quantitative Methods · Quantitative Biology 2025-10-07 Satrio Pambudi , Filippo Menolascina

Adverse drug reactions considerably impact patient outcomes and healthcare costs in cancer therapy. Using artificial intelligence to predict adverse drug reactions in real time could revolutionize oncology treatment. This study aims to…

Quantitative Methods · Quantitative Biology 2025-05-21 Fatma Zahra Abdeldjouad , Menaouer Brahami , Mohammed Sabri

We present a novel natural language query interface, the AggChecker, aimed at text summaries of relational data sets. The tool focuses on natural language claims that translate into an SQL query and a claimed query result. Similar in spirit…

Databases · Computer Science 2018-09-03 Saehan Jo , Immanuel Trummer , Weicheng Yu , Daniel Liu , Xuezhi Wang , Cong Yu , Niyati Mehta

In the realm of cancer treatment, summarizing adverse drug events (ADEs) reported by patients using prescribed drugs is crucial for enhancing pharmacovigilance practices and improving drug-related decision-making. While the volume and…

Computation and Language · Computer Science 2025-05-08 Sofia Jamil , Aryan Dabad , Bollampalli Areen Reddy , Sriparna Saha , Rajiv Misra , Adil A. Shakur

Objective. Natural language processing methods for medical auto-coding, or automatic generation of medical billing codes from electronic health records, generally assign each code independently of the others. They may thus assign codes for…

Computation and Language · Computer Science 2015-10-19 Michael Subotin , Anthony R. Davis

The extraction of pharmacological knowledge from regulatory documents has become a key focus in biomedical natural language processing, with applications ranging from adverse event monitoring to AI-assisted clinical decision support.…

Computation and Language · Computer Science 2025-10-22 Mariano Barone , Antonio Laudante , Giuseppe Riccio , Antonio Romano , Marco Postiglione , Vincenzo Moscato

Systems that can automatically define unfamiliar terms hold the promise of improving the accessibility of scientific texts, especially for readers who may lack prerequisite background knowledge. However, current systems assume a single…

A systematic review identifies and collates various clinical studies and compares data elements and results in order to provide an evidence based answer for a particular clinical question. The process is manual and involves lot of time. A…

Information Retrieval · Computer Science 2016-06-22 Tanmay Basu , Shraman Kumar , Abhishek Kalyan , Priyanka Jayaswal , Pawan Goyal , Stephen Pettifer , Siddhartha R. Jonnalagadda

With the advancements in Artificial intelligence (AI) and the accumulation of healthrelated big data, it has become increasingly feasible and commonplace to leverage machine learning technologies to analyze clinical and omics metadata to…

Genomics · Quantitative Biology 2022-04-14 Attayeb Mohsen , Lokesh P. Tripathi , Kenji Mizuguchi

Topics models, such as LDA, are widely used in Natural Language Processing. Making their output interpretable is an important area of research with applications to areas such as the enhancement of exploratory search interfaces and the…

Computation and Language · Computer Science 2019-04-01 Areej Alokaili , Nikolaos Aletras , Mark Stevenson

User-generated data sources have gained significance in uncovering Adverse Drug Reactions (ADRs), with an increasing number of discussions occurring in the digital world. However, the existing clinical corpora predominantly revolve around…

With the widespread adoption of Large Language Models (LLMs) such as GitHub Copilot and ChatGPT, developers increasingly rely on AI-assisted tools to support code generation. While LLMs can generate syntactically correct solutions for…

Software Engineering · Computer Science 2025-07-28 Yiping Jia , Zhen Ming Jiang , Shayan Noei , Ying Zou

This paper studied generating natural languages at particular contexts or situations. We proposed two novel approaches which encode the contexts into a continuous semantic representation and then decode the semantic representation into text…

Computation and Language · Computer Science 2016-12-01 Jian Tang , Yifan Yang , Sam Carton , Ming Zhang , Qiaozhu Mei

Retrieval-Augmented Generation (RAG) utilizes external knowledge to augment Large Language Models' (LLMs) reliability. For flexibility, agentic RAG employs autonomous, multi-round retrieval and reasoning to resolve queries. Although recent…

Information Retrieval · Computer Science 2025-11-10 Chao Zhang , Yuhao Wang , Derong Xu , Haoxin Zhang , Yuanjie Lyu , Yuhao Chen , Shuochen Liu , Tong Xu , Xiangyu Zhao , Yan Gao , Yao Hu , Enhong Chen

In this work, we present the first corpus for German Adverse Drug Reaction (ADR) detection in patient-generated content. The data consists of 4,169 binary annotated documents from a German patient forum, where users talk about health issues…

Computation and Language · Computer Science 2022-08-04 Lisa Raithel , Philippe Thomas , Roland Roller , Oliver Sapina , Sebastian Möller , Pierre Zweigenbaum