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By creating networks of biochemical pathways, communities of micro-organisms are able to modulate the properties of their environment and even the metabolic processes within their hosts. Next-generation high-throughput sequencing has led to…

Applications · Statistics 2023-03-28 Molly G. Hayes , Morgan G. I. Langille , Hong Gu

We present a non-equilibrium statistical mechanics description of rank abundance relations (RAR) in random community models of ecology. Specifically, we study a multi-species replicator system with quenched random interaction matrices. We…

Populations and Evolution · Quantitative Biology 2009-11-13 Yoshimi Yoshino , Tobias Galla , Kei Tokita

Studies on distribution, abundance and diversity of species revealed fascinating universalities in macroecology. Many of these patterns, like the species-area and range-abundance relationship or the year-to-year fluctuations in population…

Populations and Evolution · Quantitative Biology 2007-05-23 M. Ravasz , A. Balog , V. Marko , Z. Neda

We build a general framework which establishes a one-to-one correspondence between species abundance distribution (SAD) and species accumulation curve (SAC). The appearance rates of the species and the appearance times of individuals of…

Applications · Statistics 2022-10-25 Cheuk Ting Li , Kim-Hung Li

The mainstream crowd counting methods regress density map and integrate it to obtain counting results. Since the density representation to one head accords to its adjacent distribution, it embeds the same category objects with variant…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Qi Wang , Juncheng Wang , Junyu Gao , Yuan Yuan , Xuelong Li

Flow based models such as Real NVP are an extremely powerful approach to density estimation. However, existing flow based models are restricted to transforming continuous densities over a continuous input space into similarly continuous…

Machine Learning · Computer Science 2020-08-27 Laurent Dinh , Jascha Sohl-Dickstein , Hugo Larochelle , Razvan Pascanu

The competition for resources is a defining feature of microbial communities. In many contexts, from soils to host-associated communities, highly diverse microbes are organized into metabolic groups or guilds with similar resource…

Physics and Society · Physics 2025-05-05 Xiaowen Chen , Kyle Crocker , Seppe Kuehn , Aleksandra M. Walczak , Thierry Mora

Population analysis is persistently challenging but important, leading to the determination of diversity and function prediction of microbial community members. Here we detail our bioinformatics methods for analyzing population distribution…

Populations and Evolution · Quantitative Biology 2010-03-29 Dimitris Papamichail , Celine C. Lesaulnier , Steven Skiena , Sean R. McCorkle , Bernard Ollivier , Daniel van der Lelie

Microbial ecosystems are remarkably diverse, stable, and often consist of a balanced mixture of core and peripheral species. Here we propose a conceptual model exhibiting all these emergent properties in quantitative agreement with real…

Populations and Evolution · Quantitative Biology 2018-04-18 Akshit Goyal , Sergei Maslov

Renormalization group (RG) methods are emerging as tools in biology and computer science to support the search for simplifying structure in distributions over high-dimensional spaces. We show that mixture models can be thought of as having…

Statistical Mechanics · Physics 2024-02-09 Adam G. Kline , Stephanie E. Palmer

The microbiome constitutes a complex microbial ecology of interacting components that regulates important pathways in the host. Measurements of microbial abundances are key to learning the intricate network of interactions amongst microbes.…

Methodology · Statistics 2024-06-17 Veronica Vinciotti , Ernst Wit , Francisco Richter

Recently there has been growing interest in the use of Maximum Relative Entropy (MaxREnt) as a tool for statistical inference in ecology. In contrast, here we propose MaxREnt as a tool for applying statistical mechanics to ecology. We use…

Populations and Evolution · Quantitative Biology 2007-12-13 Roderick C. Dewar , Annabel Porte

The assessment of diversity and similarity is relevant in monitoring the status of ecosystems. The respective indicators are based on the taxonomic composition of biological communities of interest, currently estimated through the…

Applications · Statistics 2018-10-12 Fabio Divino , Johanna Ärje , Antti Penttinen , Kristian Meissner , Salme Kärkkäinen

A key challenge in differential abundance analysis of microbial samples is that the counts for each sample are compositional, resulting in biased comparisons of the absolute abundance across study groups. Normalization-based differential…

Genomics · Quantitative Biology 2024-11-26 Dylan Clark-Boucher , Brent A Coull , Harrison T Reeder , Fenglei Wang , Qi Sun , Jacqueline R Starr , Kyu Ha Lee

Raking is widely used in categorical data modeling and survey practice but faced with methodological and computational challenges. We develop a Bayesian paradigm for raking by incorporating the marginal constraints as a prior distribution…

Methodology · Statistics 2020-06-24 Yajuan Si , Peigen Zhou

An analytical approximation is derived for the Zero Sum Multinomial distribution which gives the Species Abundance Distribution in Neutral Community Models. The obtained distribution function describes well computer simulation results on…

Populations and Evolution · Quantitative Biology 2007-05-23 Z. Neda , M. Ravasz

Many natural patterns, such as the distributions of blood particles in a blood sample, proteins on cell surfaces, biological populations in their habitat, galaxies in the universe, the sequence of human genes, and the fitness in…

Computational Engineering, Finance, and Science · Computer Science 2012-05-17 Zhanshan Sam Ma

One of the central questions of metacommunity theory is how dispersal of organisms affects species diversity. Here we show that the diversity-dispersal relationship should not be studied in isolation of other abiotic and biotic flows in the…

Populations and Evolution · Quantitative Biology 2014-02-12 Bart Haegeman , Michel Loreau

Quantifying diversity is of central importance for the study of structure, function and evolution of microbial communities. The estimation of microbial diversity has received renewed attention with the advent of large-scale metagenomic…

Populations and Evolution · Quantitative Biology 2013-08-06 Bart Haegeman , Jérôme Hamelin , John Moriarty , Peter Neal , Jonathan Dushoff , Joshua S. Weitz

The growth of complex populations, such as microbial communities, forests, and cities, occurs over vastly different spatial and temporal scales. Although research in different fields has developed detailed, system-specific models to…

Populations and Evolution · Quantitative Biology 2023-09-14 Ashish B. George , James O'Dwyer
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