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While optical microscopy inspection of blood films and bone marrow aspirates by a hematologist is a crucial step in establishing diagnosis of acute leukemia, especially in low-resource settings where other diagnostic modalities might not be…

This paper introduces a novel deep-learning method for the automatic detection and segmentation of lung nodules, aimed at advancing the accuracy of early-stage lung cancer diagnosis. The proposed approach leverages a unique "Channel Squeeze…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mingxiu Sui , Jiacheng Hu , Tong Zhou , Zibo Liu , Likang Wen , Junliang Du

The current study of cell architecture of inflammation in histopathology images commonly performed for diagnosis and research purposes excludes a lot of information available on the biopsy slide. In autoimmune diseases, major outstanding…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Pranav Singh , Jacopo Cirrone

In this paper we discuss a new method for detecting leukemia in microscopic blood smear images using deep neural networks to diagnose leukemia early in blood. leukemia is considered one of the most dangerous mortality causes for a human…

Image and Video Processing · Electrical Eng. & Systems 2023-01-10 Abdelmageed Ahmed , Alaa Nagy , Ahmed Kamal , Daila Farghl

Identifying and characterizing the patient's blood samples is indispensable in diagnostics of malignance suspicious. A painstaking and sometimes subjective task is used in laboratories to manually classify white blood cells. Neural…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Daouda Diouf , Djibril Seck , Mountaga Diop , Abdoulye Ba

In numerous studies, deep learning algorithms have proven their potential for the analysis of histopathology images, for example, for revealing the subtypes of tumors or the primary origin of metastases. These models require large datasets…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Jonathan Ganz , Jonas Ammeling , Samir Jabari , Katharina Breininger , Marc Aubreville

Image segmentation is a fundamental problem in medical image analysis. In recent years, deep neural networks achieve impressive performances on many medical image segmentation tasks by supervised learning on large manually annotated data.…

Computer Vision and Pattern Recognition · Computer Science 2018-01-26 Ling Zhang , Vissagan Gopalakrishnan , Le Lu , Ronald M. Summers , Joel Moss , Jianhua Yao

The computer-aided detection (CADe) systems are developed to assist pathologists in slide assessment, increasing diagnosis efficiency and reducing missing inspections. Many studies have shown such a CADe system with deep learning approaches…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Wei-Wen Hsu , Chung-Hao Chen , Chang Hoa , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Jingjing Wang , Tao He , Yanghong Tai

Melanoma is the most lethal form of skin cancer, with an increasing incidence rate worldwide. Analyzing histological images of melanoma by localizing and classifying tissues and cell nuclei is considered the gold standard method for…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod

Lung cancer is one of the prevalence diseases in the world which cause many deaths. Detecting early stages of lung cancer is so necessary. So, modeling and simulating some intelligent medical systems is an essential which can help…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Ehsan Sadeghi Pour , Mahdi Esmaeili

Classification of HEp-2 cell patterns plays a significant role in the indirect immunofluorescence test for identifying autoimmune diseases in the human body. Many automatic HEp-2 cell classification methods have been proposed in recent…

Computer Vision and Pattern Recognition · Computer Science 2020-08-07 Saimunur Rahman , Lei Wang , Changming Sun , Luping Zhou

Lymphoma diagnosis, particularly distinguishing between subtypes, is critical for effective treatment but remains challenging due to the subtle morphological differences in histopathological images. This study presents a novel hybrid deep…

Image and Video Processing · Electrical Eng. & Systems 2024-10-10 Salah A. Aly , Ali Bakhiet , Mazen Balat

Increased levels of tumor infiltrating lymphocytes (TILs) in cancer tissue indicate favourable outcomes in many types of cancer. Manual quantification of immune cells is inaccurate and time consuming for pathologists. Our aim is to leverage…

Recent years have seen great advancements in the development of deep learning models for histopathology image analysis in digital pathology applications, evidenced by the increasingly common deployment of these models in both research and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Veena Kaustaban , Qinle Ba , Ipshita Bhattacharya , Nahil Sobh , Satarupa Mukherjee , Jim Martin , Mohammad Saleh Miri , Christoph Guetter , Amal Chaturvedi

We present a foundation modeling framework that leverages deep learning to uncover latent genetic signatures across the hematopoietic hierarchy. Our approach trains a fully connected autoencoder on multipotent progenitor cells, reducing…

Machine Learning · Computer Science 2025-03-27 Gabriel Bo , Justin Gu , Christopher Sun

In this paper, we develop a complete pipeline for stain normalization, segmentation, and classification of nuclei in hematoxylin and eosin (H&E) stained breast cancer histopathology images. In the first step, we use a CNN-based stain…

Computer Vision and Pattern Recognition · Computer Science 2018-11-12 Edwin Yuan , Junkyo Suh

In this paper, we introduced a novel feature extraction approach, named exclusive autoencoder (XAE), which is a supervised version of autoencoder (AE), able to largely improve the performance of nucleus detection and classification on…

Computer Vision and Pattern Recognition · Computer Science 2018-11-29 Chao-Hui Huang , Daniel Racoceanu

The rapid development of digital pathology and modern deep learning has facilitated the emergence of pathology foundation models that are expected to solve general pathology problems under various disease conditions in one unified model,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-10 Yutong Sun , Sichen Zhu , Peng Qiu

An estimated 300,000 new cases of leukemia are diagnosed each year which is 2.8 percent of all new cancer cases and the prevalence is rising day by day. The most dangerous and deadly type of leukemia is acute lymphoblastic leukemia (ALL),…

Image and Video Processing · Electrical Eng. & Systems 2022-08-22 Md. Taufiqul Haque Khan Tusar , Roban Khan Anik

Skin cancer is one of the most common forms of cancer and its incidence is projected to rise over the next decade. Artificial intelligence is a viable solution to the issue of providing quality care to patients in areas lacking access to…

Computer Vision and Pattern Recognition · Computer Science 2018-08-07 Nithin D Reddy