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Brain tumors are collections of abnormal cells that can develop into masses or clusters. Because they have the potential to infiltrate other tissues, they pose a risk to the patient. The main imaging technique used, MRI, may be able to…

Image and Video Processing · Electrical Eng. & Systems 2023-09-22 Razia Sultana Misu

Early detection is crucial for successful cancer treatment and increasing survivability rates, particularly in the most common forms. Ten different cancers have been identified in most of these advances that effectively use CNNs…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Hossein Molaeian , Kaveh Karamjani , Sina Teimouri , Saeed Roshani , Sobhan Roshani

DNA Methylation has been the most extensively studied epigenetic mark. Usually a change in the genotype, DNA sequence, leads to a change in the phenotype, observable characteristics of the individual. But DNA methylation, which happens in…

Genomics · Quantitative Biology 2018-07-26 Soham Chatterjee , Archana Iyer , Satya Avva , Abhai Kollara , Malaikannan Sankarasubbu

We propose DeepMiner, a framework to discover interpretable representations in deep neural networks and to build explanations for medical predictions. By probing convolutional neural networks (CNNs) trained to classify cancer in mammograms,…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Jimmy Wu , Bolei Zhou , Diondra Peck , Scott Hsieh , Vandana Dialani , Lester Mackey , Genevieve Patterson

Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, biological knowledge pertaining to a disease can…

Quantitative Methods · Quantitative Biology 2020-04-13 Thomas Gaudelet , Noel Malod-Dognin , Jon Sanchez-Valle , Vera Pancaldi , Alfonso Valencia , Natasa Przulj

While deep learning has achieved great success in many fields, one common criticism about deep learning is its lack of interpretability. In most cases, the hidden units in a deep neural network do not have a clear semantic meaning or…

Genomics · Quantitative Biology 2019-06-04 Tianle Ma , Aidong Zhang

Background and Aim: Over-fitting issue has been the reason behind deep learning technology not being successfully implemented in oral cancer images classification. The aims of this research were reducing overfitting for accurately producing…

Image and Video Processing · Electrical Eng. & Systems 2022-08-17 Prakrit Joshi , Omar Hisham Alsadoon , Abeer Alsadoon , Nada AlSallami , Tarik A. Rashid , P. W. C. Prasad , Sami Haddad

Skin cancer detection is challenging since different types of skin lesions share high similarities. This paper proposes a computer-based deep learning approach that will accurately identify different kinds of skin lesions. Deep learning…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Mst Shapna Akter , Hossain Shahriar , Sweta Sneha , Alfredo Cuzzocrea

In deep learning, transfer learning and ensemble models have shown promise in improving computer-aided disease diagnosis. However, applying the transfer learning and ensemble model is still relatively limited. Moreover, the ensemble model's…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Md Taimur Ahad , Sumaya Mustofa , Faruk Ahmed , Yousuf Rayhan Emon , Aunirudra Dey Anu

Deep learning has achieved unprecedented success in various object detection tasks with huge amounts of labeled data. However, obtaining large-scale annotations for medical images is extremely challenging due to the high demand of labour…

Image and Video Processing · Electrical Eng. & Systems 2022-03-21 Zhizhong Chai , Luyang Luo , Huangjing Lin , Hao Chen , Anjia Han , Pheng-Ann Heng

To provide the reader with a historical perspective on cancer classification approaches, we first discuss the fundamentals of the area of cancer diagnosis in this article, including the processes of cancer diagnosis and the standard…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 Farzane Tajidini

In tumoral cells, gene regulation mechanisms are severely altered, and these modifications in the regulations may be characteristic of different subtypes of cancer. However, these alterations do not necessarily induce differential…

Breast cancer has the highest incidence and second highest mortality rate for women in the US. Our study aims to utilize deep learning for benign/malignant classification of mammogram tumors using a subset of cases from the Digital Database…

Computer Vision and Pattern Recognition · Computer Science 2017-05-19 Darvin Yi , Rebecca Lynn Sawyer , David Cohn , Jared Dunnmon , Carson Lam , Xuerong Xiao , Daniel Rubin

Gene expression can be used to subtype breast cancer with improved prediction of risk of recurrence and treatment responsiveness over that obtained using routine immunohistochemistry (IHC). However, in the clinic, molecular profiling is…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 Raktim Kumar Mondol , Ewan K. A. Millar , Peter H Graham , Lois Browne , Arcot Sowmya , Erik Meijering

Despite the transformative impact of deep learning on text, audio, and image datasets, its dominance in tabular data, especially in the medical domain where data are often scarce, remains less clear. In this paper, we propose X2Graph, a…

Machine Learning · Computer Science 2025-05-30 Tu Bui , Mohamed Suliman , Aparajita Haldar , Mohammed Amer , Serban Georgescu

Determining the primary site of origin for metastatic tumors is one of the open problems in cancer care because the efficacy of treatment often depends on the cancer tissue of origin. Classification methods that can leverage tumor genomic…

Genomics · Quantitative Biology 2019-11-19 Alena Harley

The computer-aided detection (CADe) systems are developed to assist pathologists in slide assessment, increasing diagnosis efficiency and reducing missing inspections. Many studies have shown such a CADe system with deep learning approaches…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Wei-Wen Hsu , Chung-Hao Chen , Chang Hoa , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Jingjing Wang , Tao He , Yanghong Tai

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Kangning Liu , Yiqiu Shen , Nan Wu , Jakub Chłędowski , Carlos Fernandez-Granda , Krzysztof J. Geras

As the world progresses in technology and health, awareness of disease by revealing asymptomatic signs improves. It is important to detect and treat tumors in early stage as it can be life-threatening. Computer-aided technologies are used…

Image and Video Processing · Electrical Eng. & Systems 2023-07-27 Roa'a Al-Emaryeen , Sara Al-Nahhas , Fatima Himour , Waleed Mahafza , Omar Al-Kadi

Recent advances in cancer research largely rely on new developments in microscopic or molecular profiling techniques offering high level of detail with respect to either spatial or molecular features, but usually not both. Here, we present…

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