Related papers: Cortical Brain Computer Interface for Closed-Loop …
Circadian and other physiological rhythms play a key role in both normal homeostasis and disease processes. Such is the case of circadian and infradian seizure patterns observed in epilepsy. In this paper we explore a new implantable…
Long-term efficacy of internal globus pallidus (GPi) deep-brain stimulation (DBS) in DYT1 dystonia and disease progression under DBS was studied. Twenty-six patients of this open-label study were divided into two groups: (A) with single…
We propose a novel dual-loop system that synergistically combines responsive neurostimulation (RNS) implants with artificial intelligence-driven wearable devices for treating post-traumatic stress disorder (PTSD) and enabling naturalistic…
Perceived outcomes from DBS for PD were sampled for 52 cases by surveying 46 DBS recipients and 45 carers. Post-DBS experience ranged from 10-129 months. There were significant variations in perceived outcomes over time. In some cases…
Human movement disorders or paralysis lead to the loss of control of muscle activation and thus motor control. Functional Electrical Stimulation (FES) is an established and safe technique for contracting muscles by stimulating the skin…
The exact origin of tremor in Parkinson's disease remains unknown. We explain why the existing data converge on the basal ganglia-thalamo-cortical loop as a tremor generator and consider a conductance-based model of subthalamo-pallidal…
Many coordination phenomena in Nature are grounded on a synchronisation regime. In the case of brain dynamics, such self-organised process allows the neurons of particular brain regions to behave as a whole and thus directly controlling the…
During the last three decades, many studies have been conducted in the field of treatment with non-invasive methods. In this way, researchers try to use alternative methods including the use of electromagnetic waves in the treatment of…
Parkinson's disease (PD) is a neurological disorder requiring early and accurate diagnosis for effective management. Machine learning (ML) has emerged as a powerful tool to enhance PD classification and diagnostic accuracy, particularly by…
Personalized treatments are gaining momentum across all fields of medicine. Precision medicine can be applied to neuromodulatory techniques, where focused brain stimulation treatments such as repetitive transcranial magnetic stimulation…
Accurate neuronavigation is critical for effective transcranial magnetic stimulation (TMS), as stimulation outcomes depend directly on precise coil placement. Existing neuronavigation systems are often costly, complex, and prone to tracking…
Neural interfaces capable of multi-site electrical recording, on-site signal classification, and closed-loop therapy are critical for the diagnosis and treatment of neurological disorders. However, deploying machine learning algorithms on…
Transcranial magnetic stimulation (TMS) is a non-invasive and safe brain stimulation procedure with growing applications in clinical treatments and neuroscience research. However, achieving precise stimulation over prolonged sessions poses…
Cyborg in the brain-machine interface field has attracted more attention in recent years. To control a creature via a machine called cyborg method, three stages are considerable: stimulation of neurons, neural response, and the behavioral…
Loss of voluntary foot movement after spinal cord injury (SCI) can significantly limit independent mobility and quality of life. To improve motor output after injury, functional electrical stimulation (FES) is used to deliver stimulation…
This paper formulates a generalized classification algorithm with an application to classifying (or `decoding') neural activity in the brain. Medical doctors and researchers have long been interested in how brain activity correlates to body…
In 2016, the Global Burden of Disease reported that neurological disorders were the principal cause of disability-adjusted life years (DALYs) and the second leading cause of deaths. Research in the last decade has pushed neuroscience to…
We present a real-time visualization system for Transcranial Magnetic Stimulation (TMS), a non-invasive neuromodulation technique for treating various brain disorders and mental health diseases. Our solution targets the current challenges…
Parkinson's Disease (PD) is a devastating neurodegenerative disorder that affects millions of people around the globe. Many researchers are continuously working to understand PD and develop treatments to improve the condition of PD…
A new hybrid tracking controller for neuromuscular electrical stimulation is proposed. The control scheme uses sampled measurements and is designed by utilizing a numerical prediction of the state variables. The tracking error of the…