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Transient properties of different physical systems with metastable states perturbed by external white noise have been investigated. Two noise-induced phenomena, namely the noise enhanced stability and the resonant activation, are…

Statistical Mechanics · Physics 2008-10-07 B. Spagnolo , A. A. Dubkov , A. L. Pankratov , E. V. Pankratova , A. Fiasconaro , A. Ochab-Marcinek

Biological functions are generated as a result of developmental dynamics that form phenotypes governed by genotypes. The dynamical system for development is shaped through genetic evolution following natural selection based on the fitness…

Populations and Evolution · Quantitative Biology 2009-11-13 Kunihiko Kaneko

Recently, several studies have investigated the transcription process associated to specific genetic regulatory networks. In this work, we present a stochastic approach for analyzing the dynamics and effect of negative feedback loops (FBL)…

Molecular Networks · Quantitative Biology 2007-08-20 J. C. Nacher , T. Ochiai

A time-dependent bias voltage on a tunnel junction generates a time-dependent modulation of its current fluctuations, and in particular of its variance. This translates into an excitation at frequency $\tilde{f}$ generating correlations…

Mesoscale and Nanoscale Physics · Physics 2024-03-27 Clovis Farley , Edouard Pinsolle , Bertrand Reulet

Genetically identical cells in the same population can take on phenotypically variable states, leading to differentiated responses to external signals, such as nutrients and drug-induced stress. Many models and experiments have focused on a…

Molecular Networks · Quantitative Biology 2015-04-28 Thierry Mora , Aleksandra M. Walczak

Based on the measurements of noise in gene expression performed during the last decade, it has become customary to think of gene regulation in terms of a two-state model, where the promoter of a gene can stochastically switch between an ON…

Molecular Networks · Quantitative Biology 2015-06-16 Georg Rieckh , Gašper Tkačik

We analyze the dynamics of the FitzHugh-Nagumo (FHN) model in the presence of colored noise and a periodic signal. Two cases are considered: (i) the dynamics of the membrane potential is affected by the noise, (ii) the slow dynamics of the…

Biological Physics · Physics 2009-11-13 D. Valenti , G. Augello , B. Spagnolo

An important task in quantitative biology is to understand the role of stochasticity in biochemical regulation. Here, as an extension of our recent work [Phys. Rev. Lett. 107, 148101 (2011)], we study how input fluctuations affect the…

Molecular Networks · Quantitative Biology 2015-06-11 Bo Hu , David A. Kessler , Wouter-Jan Rappel , Herbert Levine

The dynamics of an ensemble of bistable elements under the influence of noise and with global time-delayed coupling is studied numerically by using a Langevin description and analytically by using 1) a Gaussian approximation and 2) a…

Statistical Mechanics · Physics 2009-11-10 Daniel Huber , Lev S. Tsimring

Cellular processes do not follow deterministic rules; even in identical environments genetically identical cells can make random choices leading to different phenotypes. This randomness originates from fluctuations present in the…

Molecular Networks · Quantitative Biology 2016-02-02 Elijah Roberts , Shay Be'er , Chris Bohrer , Rati Sharma , Michael Assaf

The occurrence of stochastic resonance in bistable systems undergoing anomalous diffusions, which arise from density-dependent fluctuations, is investigated with emphasis on the analytical formulation of the problem as well as a possible…

Statistical Mechanics · Physics 2021-03-16 F. Naha Nzoupe , Alain M. Dikande

We study a generalization of the Heston model, which consists of two coupled stochastic differential equations, one for the stock price and the other one for the volatility. We consider a cubic nonlinearity in the first equation and a…

Statistical Mechanics · Physics 2009-11-11 G. Bonanno , D. Valenti , B. Spagnolo

In this paper, we report stochastic resonance (SR) in a single electron turnstile. It has been known that SR emerges by the cooperation of a weak periodic signal and noise in a bistable system. A periodic signal produces switching between…

Quantum Physics · Physics 2007-10-16 Hisanao Akima , Shigeo Sato , Koji Nakajima

We show that the effect of stress on the reproductive fitness of noisy cell populations can be modelled as first-passage time problem, and demonstrate that even relatively short-lived fluctuations in gene expression can ensure long-term…

Biological Physics · Physics 2015-06-03 Daniel A. Charlebois , Nezar Abdennur , Mads Kaern

In this paper, we study the phase transition behavior emerging from the interactions among multiple agents in the presence of noise. We propose a simple discrete-time model in which a group of non-mobile agents form either a fixed connected…

Optimization and Control · Mathematics 2008-10-21 Jialing Liu , Vikas Yadav , Hullas Sehgal , Joshua M. Olson , Haifeng Liu , Nicola Elia

A noise source model, consisting of a pulse sequence at random times with memory, is presented. By varying the memory we can obtain variable randomness of the stochastic process. The delay time between pulses, i. e. the noise memory,…

Statistical Mechanics · Physics 2009-09-29 O. Chichigina , D. Valenti , B. Spagnolo

Stochastic resonance with white noise has been well established as a potential signal amplification mechanism in nanomechanical two-state systems. While white noise represents the archetypal stimulus for stochastic resonance, typical…

Mesoscale and Nanoscale Physics · Physics 2009-11-13 Tyler Dunn , Diego N. Guerra , Pritiraj Mohanty

We investigate the influence of intrinsic noise on stable states of a one-dimensional dynamical system that shows in its deterministic version a saddle-node bifurcation between monostable and bistable behaviour. The system is a modified…

Statistical Mechanics · Physics 2017-05-03 Johannes Falk , Marc Mendler , Barbara Drossel

In oscillatory reaction-diffusion systems, time-delay feedback can lead to the instability of uniform oscillations with respect to formation of standing waves. Here, we investigate how the presence of additive, Gaussian white noise can…

Statistical Mechanics · Physics 2016-08-17 Michael Stich , Amit K Chattopadhyay

Transitions between multiple stable states of nonlinear systems are ubiquitous in physics, chemistry, and beyond. Two types of behaviors are usually seen as mutually exclusive: unpredictable noise-induced transitions and predictable…

Statistical Mechanics · Physics 2017-10-03 Corentin Herbert , Freddy Bouchet