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We introduce a powerful student-teacher framework for the challenging problem of unsupervised anomaly detection and pixel-precise anomaly segmentation in high-resolution images. Student networks are trained to regress the output of a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-08 Paul Bergmann , Michael Fauser , David Sattlegger , Carsten Steger

Bias in classifiers is a severe issue of modern deep learning methods, especially for their application in safety- and security-critical areas. Often, the bias of a classifier is a direct consequence of a bias in the training dataset,…

Computer Vision and Pattern Recognition · Computer Science 2021-03-11 Christian Reimers , Paul Bodesheim , Jakob Runge , Joachim Denzler

Incipient anomalies present milder symptoms compared to severe ones, and are more difficult to detect and diagnose due to their close resemblance to normal operating conditions. The lack of incipient anomaly examples in the training data…

Machine Learning · Computer Science 2020-08-21 Yingshui Tan , Baihong Jin , Qiushi Cui , Xiangyu Yue , Alberto Sangiovanni Vincentelli

In this paper, we proposed to investigate unsupervised anomaly detection in Synthetic Aperture Radar (SAR) images. Our approach considers anomalies as abnormal patterns that deviate from their surroundings but without any prior knowledge of…

Computer Vision and Pattern Recognition · Computer Science 2022-10-31 Max Muzeau , Chengfang Ren , Sébastien Angelliaume , Mihai Datcu , Jean-Philippe Ovarlez

Neural net classifiers trained on data with annotated class labels can also capture apparent visual similarity among categories without being directed to do so. We study whether this observation can be extended beyond the conventional…

Computer Vision and Pattern Recognition · Computer Science 2018-05-08 Zhirong Wu , Yuanjun Xiong , Stella Yu , Dahua Lin

Due to the unsupervised nature of anomaly detection, the key to fueling deep models is finding supervisory signals. Different from current reconstruction-guided generative models and transformation-based contrastive models, we devise novel…

Machine Learning · Computer Science 2023-05-26 Hongzuo Xu , Yijie Wang , Juhui Wei , Songlei Jian , Yizhou Li , Ning Liu

Diseases are currently managed by grading systems, where patients are stratified by grading systems into stages that indicate patient risk and guide clinical management. However, these broad categories typically lack prognostic value, and…

The antinuclear antibody detection with human epithelial cells is a popular approach for autoimmune diseases diagnosis. The manual evaluation demands time, effort and capital, and automation in screening can greatly aid the physicians in…

Computer Vision and Pattern Recognition · Computer Science 2018-10-31 Vibha Gupta , Arnav Bhavsar

Local discriminative representation is needed in many medical image analysis tasks such as identifying sub-types of lesion or segmenting detailed components of anatomical structures. However, the commonly applied supervised representation…

Computer Vision and Pattern Recognition · Computer Science 2021-03-25 Huai Chen , Jieyu Li , Renzhen Wang , Yijie Huang , Fanrui Meng , Deyu Meng , Qing Peng , Lisheng Wang

Automated anomaly detection from medical images, such as MRIs and X-rays, can significantly reduce human effort in disease diagnosis. Owing to the complexity of modeling anomalies and the high cost of manual annotation by domain experts…

Image and Video Processing · Electrical Eng. & Systems 2022-09-07 Md Mahfuzur Rahman Siddiquee , Jay Shah , Teresa Wu , Catherine Chong , Todd Schwedt , Baoxin Li

Unsupervised anomaly detection in medical imaging aims to detect and localize arbitrary anomalies without requiring annotated anomalous data during training. Often, this is achieved by learning a data distribution of normal samples and…

Computer Vision and Pattern Recognition · Computer Science 2023-01-06 Carsten T. Lüth , David Zimmerer , Gregor Koehler , Paul F. Jaeger , Fabian Isensee , Jens Petersen , Klaus H. Maier-Hein

Current unsupervised anomaly localization approaches rely on generative models to learn the distribution of normal images, which is later used to identify potential anomalous regions derived from errors on the reconstructed images. However,…

Image and Video Processing · Electrical Eng. & Systems 2021-10-29 Julio Silva-Rodríguez , Valery Naranjo , Jose Dolz

The need for a large amount of labeled data in the supervised setting has led recent studies to utilize self-supervised learning to pre-train deep neural networks using unlabeled data. Many self-supervised training strategies have been…

Computer Vision and Pattern Recognition · Computer Science 2022-04-06 Mojtaba Bahrami , Mahsa Ghorbani , Nassir Navab

Evidence suggests that networks trained on large datasets generalize well not solely because of the numerous training examples, but also class diversity which encourages learning of enriched features. This raises the question of whether…

Medical image registration is crucial for various clinical and research applications including disease diagnosis or treatment planning which require alignment of images from different modalities, time points, or subjects. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Ahsan Raza Siyal , Markus Haltmeier , Ruth Steiger , Malik Galijasevic , Elke Ruth Gizewski , Astrid Ellen Grams

It is widely recognized that deep neural networks are sensitive to bias in the data. This means that during training these models are likely to learn spurious correlations between data and labels, resulting in limited generalization…

Machine Learning · Computer Science 2024-12-06 Vito Paolo Pastore , Massimiliano Ciranni , Davide Marinelli , Francesca Odone , Vittorio Murino

Medical image analysis has emerged as an essential element of contemporary healthcare, facilitating physicians in achieving expedited and precise diagnosis. Recent breakthroughs in deep learning, a subset of artificial intelligence, have…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Aimina Ali Eli , Abida Ali

In one-class-learning tasks, only the normal case (foreground) can be modeled with data, whereas the variation of all possible anomalies is too erratic to be described by samples. Thus, due to the lack of representative data, the…

Computer Vision and Pattern Recognition · Computer Science 2019-06-03 Duc Tam Nguyen , Zhongyu Lou , Michael Klar , Thomas Brox

Anomaly detection in medical imaging plays a crucial role in identifying pathological regions across various imaging modalities, such as brain MRI, liver CT, and carotid ultrasound (US). However, training fully supervised segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yuan Bi , Lucie Huang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab , Zhongliang Jiang

Anomaly detection in retinal image refers to the identification of abnormality caused by various retinal diseases/lesions, by only leveraging normal images in training phase. Normal images from healthy subjects often have regular structures…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Kang Zhou , Yuting Xiao , Jianlong Yang , Jun Cheng , Wen Liu , Weixin Luo , Zaiwang Gu , Jiang Liu , Shenghua Gao