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Prostate cancer (PCa) is the second deadliest form of cancer in males, and it can be clinically graded by examining the structural representations of Gleason tissues. This paper proposes \RV{a new method} for segmenting the Gleason tissues…

Computer Vision and Pattern Recognition · Computer Science 2021-07-27 Taimur Hassan , Bilal Hassan , Ayman El-Baz , Naoufel Werghi

Objectives: Pancreatic cancer is a lethal disease, hard to diagnose and usually results in poor prognosis and high mortality. Developing an artificial intelligence (AI) algorithm to accurately and universally predict the early cancer risk…

Breast cancer is a serious disease that inflicts millions of people each year, and the number of cases is increasing. Early detection is the best way to reduce the impact of the disease. Researchers have developed many techniques to detect…

Artificial Intelligence · Computer Science 2023-11-23 Mosab S. M. Farea , zhe chen

Digital pathology has revolutionized cancer diagnosis by leveraging Content-Based Medical Image Retrieval (CBMIR) for analyzing histopathological Whole Slide Images (WSIs). CBMIR enables searching for similar content, enhancing diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2024-01-11 Zahra Tabatabaei , Adrian Colomer , Javier Oliver Moll , Valery Naranjo

Deep learning object detection algorithm has been widely used in medical image analysis. Currently all the object detection tasks are based on the data annotated with object classes and their bounding boxes. On the other hand, medical…

Computer Vision and Pattern Recognition · Computer Science 2020-03-04 Li Xiao , Cheng Zhu , Junjun Liu , Chunlong Luo , Peifang Liu , Yi Zhao

We propose a noninvasive and dispersive framework for estimating the spatially nonuniform conductivity of brain tumors using MR images. The method consists of two components: (i) voxel-wise assignment of tumor conductivity based on…

Medical Physics · Physics 2025-09-19 Yoshiki Kubota , Yosuke Nagata , Manabu Tamura , Akimasa Hirata

Toward robust malware detection, we explore the attack surface of existing malware detection systems. We conduct root-cause analyses of the practical binary-level black-box adversarial malware examples. Additionally, we uncover the…

Machine Learning · Computer Science 2023-10-06 Ahmed Abusnaina , Yizhen Wang , Sunpreet Arora , Ke Wang , Mihai Christodorescu , David Mohaisen

Recent advances in using quantitative ultrasound (QUS) methods have provided a promising framework to non-invasively and inexpensively monitor or predict the effectiveness of therapeutic cancer responses. One of the earliest steps in using…

Computer Vision and Pattern Recognition · Computer Science 2017-01-16 Mehrdad J. Gangeh , Hamid R. Tizhoosh , Kan Wu , Dun Huang , Hadi Tadayyon , Gregory J. Czarnota

Skin cancer holds the highest incidence rate among all cancers globally. The importance of early detection cannot be overstated, as late-stage cases can be lethal. Classifying skin lesions, however, presents several challenges due to the…

Machine Learning · Computer Science 2023-06-14 Asim Naveed , Syed S. Naqvi , Tariq M. Khan , Imran Razzak

Personalized precision radiation therapy requires more than simple classification, it demands the identification of prognostic, spatially informative features and the ability to adapt treatment based on individual response. This study…

Medical Physics · Physics 2025-06-24 Hao Peng , Steve Jiang , Robert Timmerman

Purpose: We aimed to develop deep machine learning (DL) models to improve the detection and segmentation of intraprostatic lesions (IL) on bp-MRI by using whole amount prostatectomy specimen-based delineations. We also aimed to investigate…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Zhenzhen Dai , Ivan Jambor , Pekka Taimen , Milan Pantelic , Mohamed Elshaikh , Craig Rogers , Otto Ettala , Peter Boström , Hannu Aronen , Harri Merisaari , Ning Wen

Prostate cancer is one of the most common cancers in men. It is characterized by a slow growth and it can be diagnosed in an early stage by observing the Prostate Specific Antigen (PSA). However, a relapse after the primary therapy could…

Tissues and Organs · Quantitative Biology 2016-06-29 Emma Perracchione , Ilaria Stura

With the wealth of medical image data, efficient curation is essential. Assigning the sequence type to magnetic resonance images is necessary for scientific studies and artificial intelligence-based analysis. However, incomplete or missing…

Image and Video Processing · Electrical Eng. & Systems 2024-08-01 Deepa Krishnaswamy , Bálint Kovács , Stefan Denner , Steve Pieper , David Clunie , Christopher P. Bridge , Tina Kapur , Klaus H. Maier-Hein , Andrey Fedorov

Adversarial noises are useful tools to probe the weakness of deep learning based computer vision algorithms. In this paper, we describe a robust adversarial perturbation (R-AP) method to attack deep proposal-based object detectors and…

Computer Vision and Pattern Recognition · Computer Science 2019-11-05 Yuezun Li , Daniel Tian , Ming-Ching Chang , Xiao Bian , Siwei Lyu

2D and 3D tumor features are widely used in a variety of medical image analysis tasks. However, for chemotherapy response prediction, the effectiveness between different kinds of 2D and 3D features are not comprehensively assessed,…

Image and Video Processing · Electrical Eng. & Systems 2023-04-18 Neman Abdoli , Ke Zhang , Patrik Gilley , Xuxin Chen , Youkabed Sadri , Theresa C. Thai , Lauren E. Dockery , Kathleen Moore , Robert S. Mannel , Yuchen Qiu

Accurate recurrence risk stratification is crucial for optimizing treatment plans for breast cancer patients. Current prognostic tools like Oncotype DX (ODX) offer valuable genomic insights for HR+/HER2- patients but are limited by cost and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-25 Ziyu Su , Yongxin Guo , Robert Wesolowski , Gary Tozbikian , Nathaniel S. O'Connell , M. Khalid Khan Niazi , Metin N. Gurcan

Prostate cancer (PCa) is one of the most common cancers in men around the world. The most accurate method to evaluate lesion levels of PCa is microscopic inspection of stained biopsy tissue and estimate the Gleason score of tissue…

Image and Video Processing · Electrical Eng. & Systems 2020-05-12 Yi-hong Zhang , Jing Zhang , Yang Song , Chaomin Shen , Guang Yang

Deep learning models are routinely employed in computational pathology (CPath) for solving problems of diagnostic and prognostic significance. Typically, the generalization performance of CPath models is analyzed using evaluation protocols…

Image and Video Processing · Electrical Eng. & Systems 2021-06-18 Alex Foote , Amina Asif , Ayesha Azam , Tim Marshall-Cox , Nasir Rajpoot , Fayyaz Minhas

Prior literature on adversarial attack methods has mainly focused on attacking with and defending against a single threat model, e.g., perturbations bounded in Lp ball. However, multiple threat models can be combined into composite…

Computer Vision and Pattern Recognition · Computer Science 2022-07-19 Lei Hsiung , Yun-Yun Tsai , Pin-Yu Chen , Tsung-Yi Ho

Precision medicine has become a central focus in breast cancer management, advancing beyond conventional methods to deliver more precise and individualized therapies. Traditionally, histopathology images have been used primarily for…

Quantitative Methods · Quantitative Biology 2024-12-17 Suchithra Kunhoth , Somaya Al- Maadeed , Younes Akbari , Rafif Al Saady