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This paper aims at proving asymptotic stability of the radial stationary solution of a free boundary problem modeling the growth of nonnecrotic tumors with fluid-like tissues. In a previous paper we considered the case where the nutrient…

Analysis of PDEs · Mathematics 2008-06-10 Junde Wu , Shangbin Cui

We study a free boundary problem modelling the growth of non-necrotic tumors with fluid-like tissues. The fluid velocity satisfies Stokes equations with a source determined by the proliferation rate of tumor cells which depends on the…

Analysis of PDEs · Mathematics 2008-06-10 Junde Wu , Shangbin Cui

In this paper we study a mathematical model for the growth of nonnecrotic solid tumor. The tumor is assumed to be radially symmetric and its radius R(t) is an unknown function of time t as tumor growth, and the model is in the form of a…

Analysis of PDEs · Mathematics 2016-11-14 Junde Wu

In this paper, we study a free boundary problem modeling solid tumor growth with vasculature which supplies nutrients to the tumor; this is characterized in the Robin boundary condition. It was recently established [Discrete Cont. Dyn.…

Analysis of PDEs · Mathematics 2020-07-15 Yaodan Huang , Zhengce Zhang , Bei Hu

This paper is concerned with a multi-dimensional free boundary problem modeling the growth of a tumor with two species of cells: proliferating cells and quiescent cells. This free boundary problem has a unique radial stationary solution. By…

Analysis of PDEs · Mathematics 2015-06-17 Shangbin Cui

In this paper we study a free boundary problem for the growth of multi-layer tumors in necrotic phase. The tumor region is strip-like and divided into necrotic region and proliferating region with two free boundaries. The upper free…

Analysis of PDEs · Mathematics 2019-09-04 Junde Wu

This paper studies asymptotic behavior of solutions of a free boundary problem modeling the growth of tumors with two species of cells: proliferating cells and quiecent cells. In previous literatures it has been proved that this problem has…

Analysis of PDEs · Mathematics 2013-03-18 Shangbin Cui

In this paper we study asymptotic behavior of solutions for a free boundary problem modeling the growth of tumors containing two species of cells: proliferating cells and quiescent cells. This tumor model was proposed by Pettet et al in…

Analysis of PDEs · Mathematics 2007-12-18 Shangbin Cui

In this paper we study a nonlinear free boundary problem on the radial growth of a two-layer solid tumor with a quiescent core. The tumor surface and its inner interface separating the proliferating cells and the quiescent cells are both…

Analysis of PDEs · Mathematics 2025-01-09 Junde Wu , Hao Xu , Yuehong Zhuang

In this paper, we present a rigorous mathematical analysis of a free boundary problem modeling the growth of a vascular solid tumor with a necrotic core. If the vascular system supplies the nutrient concentration $\sigma$ to the tumor at a…

Analysis of PDEs · Mathematics 2019-09-20 Huijuan Song , Bei Hu , Zejia Wang

For tumor growth, the morphological instability provides a mechanism for invasion via tumor fingering and fragmentation. This work considers the asymptotic stability of a free boundary tumor model with a periodic supply of external…

Analysis of PDEs · Mathematics 2021-10-01 Yaodan Huang

We study a free boundary problem modeling multi-layer tumor growth with a small time delay $\tau$, representing the time needed for the cell to complete the replication process. The model consists of two elliptic equations which describe…

Analysis of PDEs · Mathematics 2022-06-22 Wenhua He , Ruixiang Xing , Bei Hu

In this paper, we study a nonlinear free boundary problem modeling the growth of spherically symmetric tumors. The tumor consists of a central necrotic core, an intermediate annual quiescent-cell layer, and an outer proliferating-cell…

Analysis of PDEs · Mathematics 2025-11-04 Junde Wu , Hao Xu , Yuehong Zhuang

We study a free boundary problem modeling tumor growth with a T-periodic supply $\Phi(t)$ of external nutrients. The model contains two parameters $\mu$ and $\widetilde{\sigma}$. We first show that (i) zero radially symmetric solution is…

Analysis of PDEs · Mathematics 2020-09-29 Wenhua He , Ruixiang Xing

In this paper we study asymptotic behavior of solutions for a multidimensional free boundary problem modelling the growth of nonnecrotic tumors. We first establish a general result for differential equations in Banach spaces possessing a…

Analysis of PDEs · Mathematics 2007-12-18 Shangbin Cui

In this paper we deal with a free boundary problem modeling the growth of nonnecrotic tumors.The tumor is treated as an incompressible fluid, the tissue elasticity is neglected and no chemical inhibitor species are present. We re-express…

Analysis of PDEs · Mathematics 2010-03-08 Joachim Escher , Anca-Voichita Matioc

This paper is concerned with a nonlinear free boundary problem modeling the growth of spherically symmetric tumors with angiogenesis, set with a Robin boundary condition. In which, both nonnecrotic tumors and necrotic tumors are taken into…

Analysis of PDEs · Mathematics 2020-08-21 Huijuan Song , Wentao Hu , Zejia Wang

In this paper, a two-dimensional model for the growth of multi-layer tumors is presented. The model consists of a free boundary problem for the tumor cell membrane and the tumor is supposed to grow or shrink due to cell proliferation or…

Analysis of PDEs · Mathematics 2013-06-11 Martin Kohlmann

In this paper, we consider a 3-dimensional free boundary problem modeling tumor growth with the Robin boundary condition. The system involves a positive parameter $\mu$ which reflects the intensity of tumor aggressiveness. Huang, Zhang and…

Analysis of PDEs · Mathematics 2026-01-23 Junying Chen , Ruixiang Xing

In this paper, we consider a model with tumor microenvironment involving nutrient density, extracellular matrix and matrix-degrading enzymes, which satisfy a coupled system of PDEs with a free boundary. For this coupled parabolic-hyperbolic…

Analysis of PDEs · Mathematics 2018-08-24 Rui Li , Bei Hu
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