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Autism Spectrum Disorder (ASD) is a lifelong condition that significantly influencing an individual's communication abilities and their social interactions. Early diagnosis and intervention are critical due to the profound impact of ASD's…

Computation and Language · Computer Science 2024-09-04 Jihyun Mun , Sunhee Kim , Minhwa Chung

We propose a unified optimization framework that combines neural networks with dictionary learning to model complex interactions between resting state functional MRI and behavioral data. The dictionary learning objective decomposes patient…

Machine Learning · Computer Science 2024-11-21 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart Mostofsky , Archana Venkataraman

Finding the biomarkers associated with ASD is helpful for understanding the underlying roots of the disorder and can lead to earlier diagnosis and more targeted treatment. A promising approach to identify biomarkers is using Graph Neural…

Machine Learning · Computer Science 2019-07-15 Xiaoxiao Li , Nicha C. Dvornek , Yuan Zhou , Juntang Zhuang , Pamela Ventola , James S. Duncan

This paper presents a streamlined image analysis framework for correlating behavioral measures to anatomical measures on the cortex and detecting the regions of abnormal brain-behavior correlates. We correlated a facial emotion…

Neurons and Cognition · Quantitative Biology 2025-07-02 Moo K. Chung , Kim M. Dalton , Daniel J. Kelley , Richard J. Davidson

Radiomics with deep learning models have become popular in computer-aided diagnosis and have outperformed human experts on many clinical tasks. Specifically, radiomic models based on artificial intelligence (AI) are using medical data…

Image and Video Processing · Electrical Eng. & Systems 2022-06-08 Ahmad Chaddad , Jiali li , Qizong Lu , Yujie Li , Idowu Paul Okuwobi , Camel Tanougast , Christian Desrosiers , Tamim Niazi

There has been increasing interests in learning resting-state brain functional connectivity of autism disorders using functional magnetic resonance imaging (fMRI) data. The data in a standard brain template consist of over 200,000 voxel…

Methodology · Statistics 2016-03-22 Jichun Xie , Jian Kang

While statistical analysis of a single network has received a lot of attention in recent years, with a focus on social networks, analysis of a sample of networks presents its own challenges which require a different set of analytic tools.…

Methodology · Statistics 2019-10-23 Jesús D. Arroyo-Relión , Daniel Kessler , Elizaveta Levina , Stephan F. Taylor

Theories for autism spectrum disorder (ASD) have been formulated at different levels: ranging from physiological observations to perceptual and behavioral descriptions. Understanding the physiological underpinnings of perceptual traits in…

Neurons and Cognition · Quantitative Biology 2021-12-03 Rodrigo Echeveste , Enzo Ferrante , Diego H. Milone , Inés Samengo

Autism spectrum disorder (ASD) is a neurodevelopmental disorder which results in altered behavior, social development, and communication patterns. In past years, autism prevalence has tripled, with 1 in 54 children now affected. Given that…

Deep learning models have shown strong performance in classifying Alzheimer's disease (AD) from R2* maps, but their decision-making remains opaque, raising concerns about interpretability. Previous studies suggest biases in model decisions,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Christian Tinauer , Maximilian Sackl , Stefan Ropele , Christian Langkammer

Graph kernels are kernel methods measuring graph similarity and serve as a standard tool for graph classification. However, the use of kernel methods for node classification, which is a related problem to graph representation learning, is…

Machine Learning · Computer Science 2019-10-08 Yu Tian , Long Zhao , Xi Peng , Dimitris N. Metaxas

For precision medicine and personalized treatment, we need to identify predictive markers of disease. We focus on Alzheimer's disease (AD), where magnetic resonance imaging scans provide information about the disease status. By combining…

Machine Learning · Statistics 2019-03-06 Stefan Konigorski , Shahryar Khorasani , Christoph Lippert

Autism Spectrum Disorder is a condition characterized by a typical brain development leading to impairments in social skills, communication abilities, repetitive behaviors, and sensory processing. There have been many studies combining…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Junlin Song , Yuzhuo Chen , Yuan Yao , Zetong Chen , Renhao Guo , Lida Yang , Xinyi Sui , Qihang Wang , Xijiao Li , Aihua Cao , Wei Li

We propose an integrated deep-generative framework, that jointly models complementary information from resting-state functional MRI (rs-fMRI) connectivity and diffusion tensor imaging (DTI) tractography to extract predictive biomarkers of a…

This paper considers the graph signal processing problem of anomaly detection in time series of graphs. We examine two related, complementary inference tasks: the detection of anomalous graphs within a time series, and the detection of…

Autism and Attention-Deficit Hyperactivity Disorder (ADHD) are two of the most commonly observed neurodevelopmental conditions in childhood. Providing a specific computational assessment to distinguish between the two can prove difficult…

Machine Learning · Computer Science 2024-11-19 Aditi Jaiswal , Dennis P. Wall , Peter Washington

Recurrent neural networks (RNNs) were designed for dealing with time-series data and have recently been used for creating predictive models from functional magnetic resonance imaging (fMRI) data. However, gathering large fMRI datasets for…

Image and Video Processing · Electrical Eng. & Systems 2019-10-16 Nicha C. Dvornek , Xiaoxiao Li , Juntang Zhuang , James S. Duncan

Deep learning has become an important tool for Alzheimer's disease (AD) classification from structural MRI. Many existing studies analyze individual 2D slices extracted from MRI volumes, while clinical neuroimaging practice typically relies…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Md Sifat , Sania Akter , Akif Islam , Md. Ekramul Hamid , Abu Saleh Musa Miah , Najmul Hassan , Md Abdur Rahim , Jungpil Shin

Graph Signal Processing (GSP) is a promising framework to analyze multi-dimensional neuroimaging datasets, while taking into account both the spatial and functional dependencies between brain signals. In the present work, we apply…

Computer Vision and Pattern Recognition · Computer Science 2017-08-29 Mathilde Ménoret , Nicolas Farrugia , Bastien Pasdeloup , Vincent Gripon

Various Graph Neural Networks (GNNs) have been successful in analyzing data in non-Euclidean spaces, however, they have limitations such as oversmoothing, i.e., information becomes excessively averaged as the number of hidden layers…

Machine Learning · Computer Science 2024-01-23 Jaeyoon Sim , Sooyeon Jeon , InJun Choi , Guorong Wu , Won Hwa Kim