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One of the most important surgical factors is Depth of Anesthesia (DOA) control in patients. The main problem is to overcome the uncertainty and nonlinearity of the system, due to different physiological parameters of the patient's body and…

Systems and Control · Electrical Eng. & Systems 2025-07-29 Amin Behboudifar , Chen Jing

This study introduces a Fractional Order Fuzzy PID (FOFPID) controller that uses the Whale Optimization Algorithm (WOA) to manage the Bispectral Index (BIS), keeping it within the ideal range of forty to sixty. The FOFPID controller…

Artificial Intelligence · Computer Science 2025-08-19 Lida Shahbandari , Hossein Mohseni

Particle swarm optimization (PSO) is extensively used for real parameter optimization in diverse fields of study. This paper describes an application of PSO to the problem of designing a fractional-order proportional-integral-derivative…

Other Computer Science · Computer Science 2008-11-04 Deepyaman Maiti , Ayan Acharya , Mithun Chakraborty , Amit Konar , Ramadoss Janarthanan

Estimating intervention effects in dynamical systems is crucial for outcome optimization. In medicine, such interventions arise in physiological regulation (e.g., cardiovascular system under fluid administration) and pharmacokinetics, among…

Machine Learning · Computer Science 2026-02-13 Tomer Meir , Ori Linial , Danny Eytan , Uri Shalit

Particle Swarm Optimization technique offers optimal or suboptimal solution to multidimensional rough objective functions. In this paper, this optimization technique is used for designing fractional order PID controllers that give better…

Other Computer Science · Computer Science 2008-10-22 Deepyaman Maiti , Sagnik Biswas , Amit Konar

This paper proposes an adaptive neuro-fuzzy framework to improve drug infusion rate in closed-loop control of anesthesia. The proposed controller provides a sub-optimal propofol administration rate as input to reach the desired bispectral…

Systems and Control · Electrical Eng. & Systems 2019-10-16 Mohammad Javad Khodaei , Mohammad Hadi Balaghi Inaloo , Amin Mehrvarz , Nader Jalili

Fractional-order dynamical systems were recently introduced in the field of pharmacokinetics where they proved powerful tools for modeling the absorption, disposition, distribution and excretion of drugs which are liable to anomalous…

The Proportional-Integral-Derivative Controller is widely used in industries for process control applications. Fractional-order PID controllers are known to outperform their integer-order counterparts. In this paper, we propose a new…

Other Computer Science · Computer Science 2008-11-04 Mithun Chakraborty , Deepyaman Maiti , Amit Konar

We present a novel Pharmacokinetic/Pharmacodynamic (PK/PD) model for the induction phase of anesthesia, incorporating the $\psi$-Caputo fractional derivative. By employing the Picard iterative process, we derive a solution for a…

Optimization and Control · Mathematics 2023-11-17 Mohamed Abdelaziz Zaitri , Hanaa Zitane , Delfim F. M. Torres

In this paper, an adaptive fractional controller has been designed to control chaotic systems. In fact, this controller is a fractional PID controller, which the coefficients will be tuned according to a proper adaptation mechanism. The…

Chaotic Dynamics · Physics 2012-06-13 S. H. Hosseinnia , R. Ghaderi , A. Ranjbar N. , J. Sadati , S. Momani

A fractional order (FO) PID or FOPID controller is designed for an Automatic Voltage Regulator (AVR) system with the consideration of contradictory performance objectives. An improved evolutionary Non-dominated Sorting Genetic Algorithm…

Optimization and Control · Mathematics 2013-06-18 Indranil Pan , Saptarshi Das

Fuzzy logic based PID controllers have been studied in this paper, considering several combinations of hybrid controllers by grouping the proportional, integral and derivative actions with fuzzy inferencing in different forms. Fractional…

Optimization and Control · Mathematics 2013-06-18 Saptarshi Das , Indranil Pan , Shantanu Das

In this paper, a comparative study is done on the time and frequency domain tuning strategies for fractional order (FO) PID controllers to handle higher order processes. A new fractional order template for reduced parameter modeling of…

Systems and Control · Computer Science 2012-02-28 Saptarshi Das , Suman Saha , Shantanu Das , Amitava Gupta

We obtain an analytical solution for the time-optimal control problem in the induction phase of anesthesia. Our solution is shown to align numerically with the results obtained from the conventional shooting method. The induction phase of…

Optimization and Control · Mathematics 2023-09-12 Mohamed A. Zaitri , Cristiana J. Silva , Delfim F. M. Torres

Gain and order scheduling of fractional order (FO) PI{\lambda}D{\mu} controllers are studied in this paper considering four different classes of higher order processes. The mapping between the optimum PID/FOPID controller parameters and the…

Systems and Control · Computer Science 2012-02-28 Saptarshi Das , Sayan Saha , Ayan Mukherjee , Indranil Pan , Amitava Gupta

This paper proposes the application of fractional-order PID (FOPID) controller for output voltage control of boost converters. For this purpose, parameters of the FOPID controller are calculated such that the Integral Absolute Error (IAE)…

Optimization and Control · Mathematics 2013-12-31 Farshad Merrikh-Bayat , Alireza Jamshidi

This paper presents a model-based control architecture. Based on the Medical Cyber-physical Systems (MCPS) concept, we construct a safe and reliable automatic anesthesia control closed-loop system. The control architecture uses the…

Systems and Control · Electrical Eng. & Systems 2021-12-30 Dayang Liu

A novel fractional order (FO) fuzzy Proportional-Integral-Derivative (PID) controller has been proposed in this paper which works on the closed loop error and its fractional derivative as the input and has a fractional integrator in its…

Systems and Control · Computer Science 2012-02-28 Saptarshi Das , Indranil Pan , Shantanu Das , Amitava Gupta

This paper proposes a constrained control scheme for the control of the depth of hypnosis during induction phase in clinical anesthesia. In contrast with existing control schemes for propofol delivery, the proposed scheme guarantees…

Systems and Control · Computer Science 2018-12-05 Mehdi Hosseinzadeh , Guy A. Dumont , Emanuele Garone

Closed loop anesthesia delivery (CLAD) systems can help anesthesiologists efficiently achieve and maintain desired anesthetic depth over an extended period of time. A typical CLAD system would use an anesthetic marker, calculated from…

Quantitative Methods · Quantitative Biology 2020-07-14 Sourish Chakravarty , Ayan S. Waite , John H. Abel , Emery N. Brown
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