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Expectation-Maximization (EM) algorithm is a widely used iterative algorithm for computing (local) maximum likelihood estimate (MLE). It can be used in an extensive range of problems, including the clustering of data based on the Gaussian…

Machine Learning · Statistics 2023-03-28 Pierre Houdouin , Esa Ollila , Frederic Pascal

In this paper, we develop a new estimation procedure based on the non-linear conjugate gradient (NCG) algorithm for the Box-Cox transformation cure rate model. We compare the performance of the NCG algorithm with the well-known expectation…

Computation · Statistics 2019-05-16 Suvra Pal , Souvik Roy

We propose a method for estimating coefficients in multivariate regression when there is a clustering structure to the response variables. The proposed method includes a fusion penalty, to shrink the difference in fitted values from…

Machine Learning · Statistics 2018-03-28 Bradley S. Price , Ben Sherwood

A model based clustering procedure for data of mixed type, clustMD, is developed using a latent variable model. It is proposed that a latent variable, following a mixture of Gaussian distributions, generates the observed data of mixed type.…

Methodology · Statistics 2015-11-06 Damien McParland , Isobel Claire Gormley

We develop here a semiparametric Gaussian mixture model (SGMM) for unsupervised learning with valuable spatial information taken into consideration. Specifically, we assume for each instance a random location. Then, conditional on this…

Methodology · Statistics 2025-10-21 Baichen Yu , Jin Liu , Hansheng Wang

While graphical models for continuous data (Gaussian graphical models) and discrete data (Ising models) have been extensively studied, there is little work on graphical models linking both continuous and discrete variables (mixed data),…

Machine Learning · Statistics 2016-08-22 Jie Cheng , Tianxi Li , Elizaveta Levina , Ji Zhu

Clustering mixed data presents numerous challenges inherent to the very heterogeneous nature of the variables. A clustering algorithm should be able, despite of this heterogeneity, to extract discriminant pieces of information from the…

Machine Learning · Computer Science 2022-05-10 Robin Fuchs , Denys Pommeret , Cinzia Viroli

Cluster-weighted modeling (CWM) is a mixture approach for modeling the joint probability of a response variable and a set of explanatory variables. The parameters are estimated by means of the expectation-maximization algorithm according to…

Computation · Statistics 2013-08-09 Salvatore Ingrassia , Simona C. Minotti

Modern scientific studies often collect data sets in the forms of tensors, which call for innovative statistical analysis methods. In particular, there is a pressing need for tensor clustering methods to understand the heterogeneity in the…

Methodology · Statistics 2021-04-27 Qing Mai , Xin Zhang , Yuqing Pan , Kai Deng

Heterogeneity in the cell population of cancer tissues poses many challenges in cancer diagnosis and treatment. Studying the heterogeneity in cell populations from gene expression measurement data in the context of cancer research is a…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-31 Anik Chaudhuri , Anwoy Mohanty , Manoranjan Satpathy

Data required to calibrate uncertain GCM parameterizations are often only available in limited regions or time periods, for example, observational data from field campaigns, or data generated in local high-resolution simulations. This…

Applications · Statistics 2022-10-05 Oliver R. A. Dunbar , Michael F. Howland , Tapio Schneider , Andrew M. Stuart

Expectation-Maximization (EM) algorithm is a widely used iterative algorithm for computing maximum likelihood estimate when dealing with Gaussian Mixture Model (GMM). When the sample size is smaller than the data dimension, this could lead…

Machine Learning · Statistics 2023-07-06 Pierre Houdouin , Matthieu Jonkcheere , Frederic Pascal

In many applications, multivariate samples may harbor previously unrecognized heterogeneity at the level of conditional independence or network structure. For example, in cancer biology, disease subtypes may differ with respect to…

Machine Learning · Statistics 2013-01-11 Steven M. Hill , Sach Mukherjee

Heterogeneity is a fundamental characteristic of cancer. To accommodate heterogeneity, subgroup identification has been extensively studied and broadly categorized into unsupervised and supervised analysis. Compared to unsupervised…

Methodology · Statistics 2026-02-25 Xing Qin , Xu Liu , Shuangge Ma , Mengyun Wu

Clustering algorithms are a cornerstone of machine learning applications. Recently, a quantum algorithm for clustering based on the k-means algorithm has been proposed by Kerenidis, Landman, Luongo and Prakash. Based on their work, we…

Quantum Physics · Physics 2020-01-23 Hideyuki Miyahara , Kazuyuki Aihara , Wolfgang Lechner

We introduce a general semiparametric clusterwise elliptical distribution to assess how latent cluster structure shapes continuous outcomes. Using a subjectwise representation, we first estimate cluster-specific mean vectors and a…

Methodology · Statistics 2026-04-10 Jen-Chieh Teng , Sheng-Hsin Fan , Chin-Tsang Chiang , Ming-Yueh Huang , Alvin Lim

Clustering high-dimensional data is especially challenging when cluster distributions are heavy tailed and only approximately elliptical. Existing high-dimensional methods are largely built for Gaussian or other light-tailed models, whereas…

Methodology · Statistics 2026-05-12 Long Feng , Dan Zhuang

Urban structure detection is a basic task in urban geography. Clustering is a core technology to detect the patterns of urban spatial structure, urban functional region, and so on. In big data era, diverse urban sensing datasets recording…

Social and Information Networks · Computer Science 2017-07-13 Xin Lin , Haifeng Li , Yan Zhang , Lei Gao , Ling Zhao , Min Deng

The identification of different homogeneous groups of observations and their appropriate analysis in PLS-SEM has become a critical issue in many appli- cation fields. Usually, both SEM and PLS-SEM assume the homogeneity of all units on…

Methodology · Statistics 2018-10-18 Mario Fordellone , Maurizio Vichi

In this paper, we consider the problem of estimating multiple graphical models simultaneously using the fused lasso penalty, which encourages adjacent graphs to share similar structures. A motivating example is the analysis of brain…

Machine Learning · Computer Science 2014-01-03 Sen Yang , Zhaosong Lu , Xiaotong Shen , Peter Wonka , Jieping Ye