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Data-mining techniques have frequently been developed for Spontaneous reporting databases. These techniques aim to find adverse drug events accurately and efficiently. Spontaneous reporting databases are prone to missing information, under…

Computational Engineering, Finance, and Science · Computer Science 2013-07-04 Jenna Reps , Jan Feyereisl , Jonathan M. Garibaldi , Uwe Aickelin , Jack E. Gibson , Richard B. Hubbard

Predicting medications is a crucial task in many intelligent healthcare systems. It can assist doctors in making informed medication decisions for patients according to electronic medical records (EMRs). However, medication prediction is a…

Artificial Intelligence · Computer Science 2022-05-02 Yang An , Bo Jin , Xiaopeng Wei

Longitudinal observational databases have become a recent interest in the post marketing drug surveillance community due to their ability of presenting a new perspective for detecting negative side effects. Algorithms mining longitudinal…

Machine Learning · Computer Science 2013-07-08 Jenna Reps , Jonathan M. Garibaldi , Uwe Aickelin , Daniele Soria , Jack E. Gibson , Richard B. Hubbard

Neural Network (NN) models provide potential to speed up the drug discovery process and reduce its failure rates. The success of NN models require uncertainty quantification (UQ) as drug discovery explores chemical space beyond the training…

Machine Learning · Computer Science 2022-11-01 Ya Ju Fan , Jonathan E. Allen , Kevin S. McLoughlin , Da Shi , Brian J. Bennion , Xiaohua Zhang , Felice C. Lightstone

Appropriate dosing of radiation is crucial to patient safety in radiotherapy. Current quality assurance depends heavily on a peer-review process, where the physicians' peer review on each patient's treatment plan, including dose and…

Machine Learning · Computer Science 2021-12-01 Qiongge Li , Jean Wright , Russell Hales , Ranh Voong , Todd McNutt

Doc2Query -- the process of expanding the content of a document before indexing using a sequence-to-sequence model -- has emerged as a prominent technique for improving the first-stage retrieval effectiveness of search engines. However,…

Information Retrieval · Computer Science 2023-02-28 Mitko Gospodinov , Sean MacAvaney , Craig Macdonald

The continually advancing quality of deepfake technology exacerbates the threats of disinformation, fraud, and harassment by making maliciously-generated synthetic content increasingly difficult to distinguish from reality. We introduce a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Jack Richings , Margaux Leblanc , Ian Groves , Victoria Nockles

Automatically detecting inappropriate content can be a difficult NLP task, requiring understanding context and innuendo, not just identifying specific keywords. Due to the large quantity of online user-generated content, automatic detection…

Computation and Language · Computer Science 2016-08-12 Stefania Raimondo , Frank Rudzicz

Causal discovery between collections of time-series data can help diagnose causes of symptoms and hopefully prevent faults before they occur. However, reliable causal discovery can be very challenging, especially when the data acquisition…

Machine Learning · Computer Science 2023-01-12 Haonan Chen , Bo Yuan Chang , Mohamed A. Naiel , Georges Younes , Steven Wardell , Stan Kleinikkink , John S. Zelek

In healthcare, the emphasis on patient safety and the minimization of medical errors cannot be overstated. Despite concerted efforts, many healthcare systems, especially in low-resource regions, still grapple with preventing these errors…

Computation and Language · Computer Science 2023-12-21 M Tran , C Sun

Leveraging large historical data in electronic health record (EHR), we developed Doctor AI, a generic predictive model that covers observed medical conditions and medication uses. Doctor AI is a temporal model using recurrent neural…

Machine Learning · Computer Science 2016-09-29 Edward Choi , Mohammad Taha Bahadori , Andy Schuetz , Walter F. Stewart , Jimeng Sun

We consider the problem of online resource allocation with average budget constraints. At each time point the decision maker makes an irrevocable decision of whether to accept or reject a request before the next request arrives with the…

Methodology · Statistics 2025-09-29 Ruicheng Ao , Hongyu Chen , David Simchi-Levi , Feng Zhu

Adverse drug reaction (ADR) is widely concerned for public health issue. ADRs are one of most common causes to withdraw some drugs from market. Prescription event monitoring (PEM) is an important approach to detect the adverse drug…

Machine Learning · Computer Science 2014-09-03 Yihui Liu , Uwe Aickelin

Despite recent progress on conversational systems, they still do not perform smoothly and coherently when faced with ambiguous requests. When questions are unclear, conversational systems should have the ability to ask clarifying questions,…

Information Retrieval · Computer Science 2022-08-10 Negar Arabzadeh , Mahsa Seifikar , Charles L. A. Clarke

Background: Accurate and timely detection of public health events of international concern is necessary to help support risk assessment and response and save lives. Novel event-based methods that use the World Wide Web as a signal source…

Computation and Language · Computer Science 2011-10-17 Nigel Collier

Health care professionals rely on treatment search engines to efficiently find adequate clinical trials and early access programs for their patients. However, doctors lose trust in the system if its underlying processes are unclear and…

Information Retrieval · Computer Science 2021-10-26 Edeline Contempré , Zoltán Szlávik , Majid Mohammadi , Erick Velazquez , Annette ten Teije , Ilaria Tiddi

At the hospital, the dispersion of information regarding anti-cancer treatment makes it difficult to extract. We proposed a solution capable of identifying dates, drugs and their temporal relationship within free-text oncology reports with…

Quantitative Methods · Quantitative Biology 2024-10-15 Valentin Pohyer , Elizabeth Fabre , Stéphane Oudard , Laure Fournier , Bastien Rance

Predicting the chemical properties of compounds is crucial in discovering novel materials and drugs with specific desired characteristics. Recent significant advances in machine learning technologies have enabled automatic predictive…

Quantitative Methods · Quantitative Biology 2021-12-10 Yang Liu , Hisashi Kashima

Adverse drug reaction (ADR) prediction plays a crucial role in both health care and drug discovery for reducing patient mortality and enhancing drug safety. Recently, many studies have been devoted to effectively predict the drug-ADRs…

Information Retrieval · Computer Science 2023-08-08 Haoxuan Li , Taojun Hu , Zetong Xiong , Chunyuan Zheng , Fuli Feng , Xiangnan He , Xiao-Hua Zhou

Adverse drug reactions (ADRs) are one of the leading causes of mortality in health care. Current ADR surveillance systems are often associated with a substantial time lag before such events are officially published. On the other hand,…

Information Retrieval · Computer Science 2018-02-15 Shashank Gupta , Manish Gupta , Vasudeva Varma , Sachin Pawar , Nitin Ramrakhiyani , Girish K. Palshikar