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Autism spectrum disorder (ASD) is a neurodevelopmental condition impacting high-level cognitive processing and social behavior. Recognizing the distributed nature of brain function, neuroscientists are exploiting the connectome to aid with…

Neurons and Cognition · Quantitative Biology 2019-09-26 Ai Wern Chung , Markus D. Schirmer

This paper studies the problem of learning causal structures from observational data. We reformulate the Structural Equation Model (SEM) with additive noises in a form parameterized by binary graph adjacency matrix and show that, if the…

Machine Learning · Computer Science 2022-01-11 Ignavier Ng , Shengyu Zhu , Zhuangyan Fang , Haoyang Li , Zhitang Chen , Jun Wang

Emerging evidence showed that major depressive disorder (MDD) is associated with disruptions of brain structural and functional networks, rather than impairment of isolated brain region. Thus, connectome-based models capable of predicting…

Neurons and Cognition · Quantitative Biology 2021-10-18 Aya Kabbara , Gabriel Robert , Mohamad Khalil , Marc Verin , Pascal Benquet , Mahmoud Hassan

Autism Spectrum Disorder (ASD) is a complex neurological condition characterized by varied developmental impairments, especially in communication and social interaction. Accurate and early diagnosis of ASD is crucial for effective…

Machine Learning · Computer Science 2025-03-18 Suchanuch Piriyasatit , Chaohao Yuan , Ercan Engin Kuruoglu

Functional connectivity (FC) refers to the investigation of interactions between brain regions to understand integration of neural activity in several regions. FC is often estimated using functional magnetic resonance images (fMRI). There…

Applications · Statistics 2023-01-24 Nathan Tung , Jerome Sanes , Eli Upfal , Ani Eloyan

Constructing the adjacency graph is fundamental to graph-based clustering. Graph learning in kernel space has shown impressive performance on a number of benchmark data sets. However, its performance is largely determined by the chosen…

Machine Learning · Computer Science 2019-03-15 Zhao Kang , Liangjian Wen , Wenyu Chen , Zenglin Xu

Diagnosing Autism Spectrum Disorder (ASD) is a challenging problem, and is based purely on behavioral descriptions of symptomology (DSM-5/ICD-10), and requires informants to observe children with disorder across different settings (e.g.…

Neurons and Cognition · Quantitative Biology 2020-03-04 Taban Eslami , Joseph S. Raiker , Fahad Saeed

Identifying structures in common forms the basis for networked systems design and optimization. However, real structures represented by graphs are often of varying sizes, leading to the low accuracy of traditional graph classification…

Machine Learning · Computer Science 2024-09-04 Xiaoyu Zhang , Wenchuan Yang , Jiawei Feng , Bitao Dai , Tianci Bu , Xin Lu

Charting the lifespan evolutionary trajectory of brain function serves as the normative standard for preventing mental disorders during brain development and aging. Although numerous MRI studies have mapped the structural connectome for…

Neural and Evolutionary Computing · Computer Science 2025-06-04 Shiang Hu , Xiaolong Huang , Yifan Hu , Xue Xiang , Xiaoliang Sheng , Debin Zhou , Pedro A. Valdes-Sosa

The lack of anisotropic kernels in graph neural networks (GNNs) strongly limits their expressiveness, contributing to well-known issues such as over-smoothing. To overcome this limitation, we propose the first globally consistent…

Machine Learning · Computer Science 2021-04-09 Dominique Beaini , Saro Passaro , Vincent Létourneau , William L. Hamilton , Gabriele Corso , Pietro Liò

Generative models and inferential autoencoders mostly make use of $\ell_2$ norm in their optimization objectives. In order to generate perceptually better images, this short paper theoretically discusses how to use Structural Similarity…

Machine Learning · Computer Science 2020-07-01 Benyamin Ghojogh , Fakhri Karray , Mark Crowley

The traditional methods for detecting autism spectrum disorder (ASD) are expensive, subjective, and time-consuming, often taking years for a diagnosis, with many children growing well into adolescence and even adulthood before finally…

Neurons and Cognition · Quantitative Biology 2022-11-15 James Orme-Rogers , Ajitesh Srivastava

SpectralNet is a graph clustering method that uses neural network to find an embedding that separates the data. So far it was only used with $k$-nn graphs, which are usually constructed using a distance metric (e.g., Euclidean distance).…

Machine Learning · Computer Science 2023-02-28 Mashaan Alshammari , John Stavrakakis , Adel F. Ahmed , Masahiro Takatsuka

Autism spectrum disorder (ASD) affects the brain connectivity at different levels. Nonetheless, non-invasively distinguishing such effects using magnetic resonance imaging (MRI) remains very challenging to machine learning diagnostic…

Machine Learning · Computer Science 2020-04-29 Ismail Bilgen , Goktug Guvercin , Islem Rekik

In the deep metric learning approach to image segmentation, a convolutional net densely generates feature vectors at the pixels of an image. Pairs of feature vectors are trained to be similar or different, depending on whether the…

Computer Vision and Pattern Recognition · Computer Science 2019-02-04 Kyle Luther , H. Sebastian Seung

We present a method to segment MRI scans of the human brain into ischemic stroke lesion and normal tissues. We propose a neural network architecture in the form of a standard encoder-decoder where predictions are guided by a spatial…

Image and Video Processing · Electrical Eng. & Systems 2021-09-21 Alex Wong , Allison Chen , Yangchao Wu , Safa Cicek , Alexandre Tiard , Byung-Woo Hong , Stefano Soatto

Recent developments in network neuroscience have highlighted the importance of developing techniques for analyzing and modeling brain networks. A particularly powerful approach for studying complex neural systems is to formulate generative…

Neurons and Cognition · Quantitative Biology 2022-09-09 Viplove Arora , Enrico Amico , Joaquín Goñi , Mario Ventresca

A novel kernel-based support vector machine (SVM) for graph classification is proposed. The SVM feature space mapping consists of a sequence of graph convolutional layers, which generates a vector space representation for each vertex,…

Machine Learning · Computer Science 2020-08-05 Padraig Corcoran

The availability of graph data with node attributes that can be either discrete or real-valued is constantly increasing. While existing kernel methods are effective techniques for dealing with graphs having discrete node labels, their…

Machine Learning · Computer Science 2024-10-30 Giovanni Da San Martino , Nicolò Navarin , Alessandro Sperduti

Dealing with land cover classification of the new image sources has also turned to be a complex problem requiring large amount of memory and processing time. In order to cope with these problems, statistical learning has greatly helped in…

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