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In clinical trials, there is potential to improve precision and reduce the required sample size by appropriately adjusting for baseline variables in the statistical analysis. This is called covariate adjustment. Despite recommendations by…

Methodology · Statistics 2022-06-20 Kelly Van Lancker , Joshua Betz , Michael Rosenblum

In this paper, we propose a propensity score adapted variable selection procedure to select covariates for inclusion in propensity score models, in order to eliminate confounding bias and improve statistical efficiency in observational…

Methodology · Statistics 2021-09-14 Kangjie Zhou , Jinzhu Jia

Logistic regression involving high-dimensional covariates is a practically important problem. Often the goal is variable selection, i.e., determining which few of the many covariates are associated with the binary response. Unfortunately,…

Computation · Statistics 2025-02-18 Yiqi Tang , Ryan Martin

We consider the problems of variable selection and estimation in nonparametric additive regression models for high-dimensional data. In recent years, several methods have been proposed to model nonlinear relationships when the number of…

Methodology · Statistics 2013-10-07 Linn Cecilie Bergersen , Kukatharmini Tharmaratnam , Ingrid K. Glad

When fitting statistical models, some predictors are often found to be correlated with each other, and functioning together. Many group variable selection methods are developed to select the groups of predictors that are closely related to…

Methodology · Statistics 2021-03-25 Zhiyuan Li

Clinical research often focuses on complex traits in which many variables play a role in mechanisms driving, or curing, diseases. Clinical prediction is hard when data is high-dimensional, but additional information, like domain knowledge…

Methodology · Statistics 2020-05-21 Mirrelijn M. van Nee , Lodewyk F. A. Wessels , Mark A. van de Wiel

Fitting nonlinear dynamical models to sparse and noisy observations is fundamentally challenging. Identifying dynamics requires data assimilation (DA) to estimate system states, but DA requires an accurate dynamical model. To break this…

Machine Learning · Computer Science 2024-09-12 Vadim Zinchenko , David S. Greenberg

Machine learning models are prone to capturing the spurious correlations between non-causal attributes and classes, with counterfactual data augmentation being a promising direction for breaking these spurious associations. However,…

Machine Learning · Computer Science 2025-07-11 Xiaoling Zhou , Ou Wu , Michael K. Ng

An important problem in the analysis of high-dimensional omics data is to identify subsets of molecular variables that are associated with a phenotype of interest. This requires addressing the challenges of high dimensionality, strong…

Methodology · Statistics 2022-04-05 Fan Wang , Sylvia Richardson , Steven M. Hill

Variable selection is a procedure to attain the truly important predictors from inputs. Complex nonlinear dependencies and strong coupling pose great challenges for variable selection in high-dimensional data. In addition, real-world…

Methodology · Statistics 2023-07-04 Keyao Wang , Huiwen Wang , Jichang Zhao , Lihong Wang

Linear discriminant analysis (LDA) is a classical method for dimensionality reduction, where discriminant vectors are sought to project data to a lower dimensional space for optimal separability of classes. Several recent papers have…

Computation · Statistics 2022-03-04 Summer Atkins , Gudmundur Einarsson , Brendan Ames , Line Clemmensen

The use of quadratic discriminant analysis (QDA) or its regularized version (R-QDA) for classification is often not recommended, due to its well-acknowledged high sensitivity to the estimation noise of the covariance matrix. This becomes…

Machine Learning · Statistics 2020-09-15 Amine Bejaoui , Khalil Elkhalil , Abla Kammoun , Mohamed Slim Alouni , Tarek Al-Naffouri

Factor models are a class of powerful statistical models that have been widely used to deal with dependent measurements that arise frequently from various applications from genomics and neuroscience to economics and finance. As data are…

Methodology · Statistics 2018-08-14 Jianqing Fan , Kaizheng Wang , Yiqiao Zhong , Ziwei Zhu

This paper presents a robust version of the stratified sampling method when multiple uncertain input models are considered for stochastic simulation. Various variance reduction techniques have demonstrated their superior performance in…

Optimization and Control · Mathematics 2023-06-16 Seung Min Baik , Eunshin Byon , Young Myoung Ko

We present a new procedure for enhanced variable selection for component-wise gradient boosting. Statistical boosting is a computational approach that emerged from machine learning, which allows to fit regression models in the presence of…

Ordinary differential equations (ODEs) provide a powerful framework for modeling dynamic systems arising in a wide range of scientific domains. However, most existing ODE methods focus on a single system, and do not adequately address the…

Methodology · Statistics 2026-04-08 Shuoxun Xu , Zijian Guo , Brooke R. Staveland , Robert T. Knight , Lexin Li

The ever-increasing quantity of multivariate process data is driving a need for skilled engineers to analyze, interpret, and build models from such data. Multivariate data analytics relies heavily on linear algebra, optimization, and…

Machine Learning · Statistics 2022-11-08 Joachim Schaeffer , Richard Braatz

We revisit vertex discriminant analysis (VDA) from the perspective of proximal distance algorithms. By specifying sparsity sets as constraints that directly control the number of active features, VDA is able to fit multiclass classifiers…

Computation · Statistics 2022-03-22 Alfonso Landeros , Tong Tong Wu , Kenneth Lange

The challenge of Out-of-Distribution (OOD) generalization poses a foundational concern for the application of machine learning algorithms to risk-sensitive areas. Inspired by traditional importance weighting and propensity weighting…

Machine Learning · Computer Science 2025-02-12 Han Yu , Yue He , Renzhe Xu , Dongbai Li , Jiayin Zhang , Wenchao Zou , Peng Cui

Recent studies have addressed the concern of detecting and rejecting the out-of-distribution (OOD) samples as a major challenge in the safe deployment of deep learning (DL) models. It is desired that the DL model should only be confident…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Umar Khalid , Ashkan Esmaeili , Nazmul Karim , Nazanin Rahnavard
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