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Confocal Raman microscopy, a highly specific and label-free technique for the microscale study of thick samples, often presents difficulties due to weak Raman signals. Inhomogeneous samples introduce wavefront aberrations that further…
Imaging through a strongly diffusive medium remains an outstanding challenge in particular in association with applications in biological and medical imaging. Here we propose a method based on a single-photon time-of-flight camera that…
Real-time monitoring of dynamic biological processes in the body is critical to understanding disease progression and treatment response. This data, for instance, can help address the lower than 50% response rates to cancer immunotherapy.…
A simple imaging system together with complex semidefinite programming is used to generate the transmission matrix of a multimode fiber. Once the transmission matrix is acquired, we can modulate the phase of the input signal to induce…
Deep learning-based methods have achieved promising results on surgical instrument segmentation. However, the high computation cost may limit the application of deep models to time-sensitive tasks such as online surgical video analysis for…
We introduce a system capable of focusing light through a multimode fiber in 37ms, one order of magnitude faster than demonstrated in previous reports. As a result, the focus spot can be maintained during significant bending of the fiber,…
All-optical image processing offers a high-speed, energy-efficient alternative to conventional electronic systems by leveraging the wave nature of light for parallel computation. However, traditional optical processors rely on bulky…
Ultrasound vascular imaging is limited by acoustic diffraction, restricting visualization of microvessels essential for understanding organ function and disease. Label-free super-resolution methods exploiting endogenous red blood cells have…
Objective: Probe-based confocal endomicroscopy is an emerging high-magnification optical imaging technique that provides in vivo and in situ cellular-level imaging for real-time assessment of tissue pathology. Endomicroscopy could…
Existing three-dimensional (3-D) compressive sensing-based millimeter-wave (MMW) imaging methods require a large-scale storage of the sensing matrix and immense computations owing to the high dimension matrix-vector model employed in the…
We introduce a wide-field magneto-optical microscope to probe magnetization dynamics with femtosecond temporal and sub-micrometer spatial resolution. We carefully calibrate the non-linear dependency between the magnetization of the sample…
Magnetic particle imaging (MPI) is a tracer-based imaging modality that detects superparamagnetic iron oxide nanoparticles in vivo, with applications in cancer cell tracking, lymph node mapping, and cell therapy monitoring. We introduce a…
Optical tomographic imaging of biological specimen bases its reliability on the combination of both accurate experimental measures and advanced computational techniques. In general, due to high scattering and absorption in most of the…
Space-division multiplexing (SDM) with multicore fibers (MCFs) is envisioned to overcome the capacity crunch in optical fiber communications. Within these systems, the coupling optics that connect single-mode fibers (SMFs) to MCFs are key…
We study the problem of inferring an object-centric scene representation from a single image, aiming to derive a representation that explains the image formation process, captures the scene's 3D nature, and is learned without supervision.…
Super-resolution fluorescence microscopy provides unprecedented insight into cellular and subcellular structures. However, going "beyond the diffraction barrier" comes at a price since most far-field super-resolution imaging techniques…
Extended depth of focus (EDOF) optics can enable lower complexity optical imaging systems when compared to active focusing solutions. With existing EDOF optics, however, it is difficult to achieve high resolution and high collection…
We present a self-supervised learning-based pipeline for dense 3D reconstruction from full-length monocular endoscopic videos without a priori modeling of anatomy or shading. Our method only relies on unlabeled monocular endoscopic videos…
We present a low-loss, compact, hollow core optical fibre (HCF) cell integrated with single mode fibre (SMF). The cell is designed to be filled with atomic vapour and used as a component in photonic quantum technologies, with applications…
The formation of organized optical states in multidimensional systems is crucial for understanding light-matter interaction and advancing light-shaping technologies. Here, we report the observation of a self-localized, ultrafast pencil beam…