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Glioblastoma multiforme (GBM) is a fast-growing and highly invasive brain tumour, it tends to occur in adults between the ages of 45 and 70 and it accounts for 52 percent of all primary brain tumours. Usually, GBMs are detected by magnetic…

Image and Video Processing · Electrical Eng. & Systems 2020-04-21 Matteo Rucco , Lorenzo Falsetti , Giovanna Viticchi

Gliomas are aggressive brain tumors that require accurate imaging-based diagnosis, with segmentation playing a critical role in evaluating morphology and treatment decisions. Manual delineation of gliomas is time-consuming and prone to…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Cecilia Diana-Albelda , Roberto Alcover-Couso , Álvaro García-Martín , Jesus Bescos , Marcos Escudero-Viñolo

Background: This research aims to improve glioblastoma survival prediction by integrating MR images, clinical and molecular-pathologic data in a transformer-based deep learning model, addressing data heterogeneity and performance…

Glioblastoma (GBM) is one of the most aggressive and lethal human cancers. Intra-tumoral genetic heterogeneity poses a significant challenge for treatment. Biopsy is invasive, which motivates the development of non-invasive, MRI-based…

Survival prediction models can potentially be used to guide treatment of glioblastoma patients. However, currently available MR imaging biomarkers holding prognostic information are often challenging to interpret, have difficulties…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Sveinn Pálsson , Stefano Cerri , Hans Skovgaard Poulsen , Thomas Urup , Ian Law , Koen Van Leemput

Glioblastoma brain tumors are highly malignant and often require early detection and accurate segmentation for effective treatment. We are proposing two deep learning models in this paper, namely UNet and Deeplabv3, for the detection and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-02 Utkarsh Maurya , Appisetty Krishna Kalyan , Swapnil Bohidar , S. Sivakumar

GBM (Glioblastoma multiforme) is the most aggressive type of brain tumor in adults that has a short survival rate even after aggressive treatment with surgery and radiation therapy. The changes on magnetic resonance imaging (MRI) for…

Image and Video Processing · Electrical Eng. & Systems 2023-06-07 M. S. Sadique , W. Farzana , A. Temtam , E. Lappinen , A. Vossough , K. M. Iftekharuddin

Gender disparities in health outcomes have garnered significant attention, prompting investigations into their underlying causes. Glioblastoma (GBM), a devastating and highly aggressive form of brain tumor, serves as a case for such…

Applications · Statistics 2023-08-09 Solomon Eshun

Glioblastoma is one of the most aggressive and deadliest types of brain cancer, with low survival rates compared to other types of cancer. Analysis of Magnetic Resonance Imaging (MRI) scans is one of the most effective methods for the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 Huafeng Liu , Benjamin Dowdell , Todd Engelder , Zarah Pulmano , Nicolas Osa , Arko Barman

Glioblastoma is a highly invasive brain tumor with rapid progression rates. Recent studies have shown that glioblastoma molecular subtype classification serves as a significant biomarker for effective targeted therapy selection. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Shekhnaz Idrissova , Islem Rekik

Glioblastoma is a highly aggressive form of brain cancer characterized by rapid progression and poor prognosis. Despite advances in treatment, the underlying genetic mechanisms driving this aggressiveness remain poorly understood. In this…

Quantitative Methods · Quantitative Biology 2025-05-20 Ahmad Berjaoui , Louis Roussel , Eduardo Hugo Sanchez , Elizabeth Cohen-Jonathan Moyal

Mathematical oncology provides unique and invaluable insights into tumour growth on both the microscopic and macroscopic levels. This review presents state-of-the-art modelling techniques and focuses on their role in understanding…

Predicting the infiltration of Glioblastoma (GBM) from medical MRI scans is crucial for understanding tumor growth dynamics and designing personalized radiotherapy treatment plans.Mathematical models of GBM growth can complement the data in…

Machine Learning · Computer Science 2024-08-19 Ray Zirui Zhang , Ivan Ezhov , Michal Balcerak , Andy Zhu , Benedikt Wiestler , Bjoern Menze , John S. Lowengrub

Currently, there is a noticeable lack of AI in the medical field to support doctors in treating heterogenous brain tumors such as Glioblastoma Multiforme (GBM), the deadliest human cancer in the world with a five-year survival rate of just…

Artificial Intelligence · Computer Science 2025-12-09 Krishna Arun , Moinak Bhattachrya , Paras Goel

We propose a curve-based Riemannian-geometric approach for general shape-based statistical analyses of tumors obtained from radiologic images. A key component of the framework is a suitable metric that (1) enables comparisons of tumor…

Applications · Statistics 2017-02-07 Karthik Bharath , Sebastian Kurtek , Arvind Rao , Veerabhadran Baladandayuthapani

Precise prognostic modeling of glioblastoma (GBM) under varying treatment interventions is essential for optimizing clinical outcomes. While generative AI has shown promise in simulating GBM evolution, existing methods typically treat…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Chenhui Wang , Boyun Zheng , Liuxin Bao , Zhihao Peng , Peter Y. M. Woo , Hongming Shan , Yixuan Yuan

Glioblastoma is one of the most aggressive and common brain tumors, with a median survival of 10-15 months. Predicting Overall Survival (OS) is critical for personalizing treatment strategies and aligning clinical decisions with patient…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Yin Lin , Riccardo Barbieri , Domenico Aquino , Giuseppe Lauria , Marina Grisoli , Elena De Momi , Alberto Redaelli , Simona Ferrante

Glioblastoma is a highly invasive brain tumor, whose cells infiltrate surrounding normal brain tissue beyond the lesion outlines visible in the current medical scans. These infiltrative cells are treated mainly by radiotherapy. Existing…

Accurate prognosis for Glioblastoma (GBM) using deep learning (DL) is hindered by extreme spatial and structural heterogeneity. Moreover, inconsistent MRI acquisition protocols across institutions hinder generalizability of models.…

Machine Learning · Computer Science 2026-02-13 Ankita Paul , Wenyi Wang

Glioblastoma (GBM) is an aggressive primary brain tumor with a median survival of approximately 15 months. In clinical practice, the Stupp protocol serves as the standard first-line treatment. However, patients exhibit highly heterogeneous…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Alexandre G. Leclercq , Sébastien Bougleux , Noémie N. Moreau , Alexis Desmonts , Romain Hérault , Aurélien Corroyer-Dulmont
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