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Heat enhancement at the target in a High Intensity Focused Ultrasound (HIFU) field is investigated by considering the effects of the injection of microbubbles in the vicinity of the tumor to be ablated. The interaction between the bubble…

Fluid Dynamics · Physics 2025-11-27 Aswin Gnanaskandan , Chao-Tsung Hsiao , Georges Chahine

Hyperthermia therapy (HT) is used to treat diseases through heating of high temperature usually in conjunction with some other medical therapeutics like chemotherapy and radiotherapy. In this study, we propose a promising thermostatic…

Medical Physics · Physics 2021-09-14 Yuchan Wang , Yuening Wang , Yuan Jie , Paul Carson

High Intensity Focused Ultrasound (HIFU) is a promising therapy for thermal ablation and hyperthermia, characterised by it noninvasiveness, high penetration depth. Effective HIFU thermo-therapy requires the ability to accurately predict…

Medical Physics · Physics 2020-07-14 Gajendra Singh , Anup Paul , Himanshu Shekhar , Abhijit Paul

During laser and ultrasound thermotherapy it is always desirable to have a precise necrosis of deeply seated tumor preserving the adjoining healthy tissue with minimum thermally induced nociceptive pain sensation to the patient. The aim of…

Medical Physics · Physics 2020-07-29 Abhijit Paul , Anup Paul

A clinical case study of high-intensity focused ultrasound (HIFU) treatment in the uterine fibroid was conducted. During the therapy, poor heating efficacy was observed which could be attributed to several factors such as the local…

Medical Physics · Physics 2019-10-29 Visa Suomi , Antti Viitala , Teija Sainio , Gaber Komar , Roberto Blanco Sequeiros

Targeted therapeutic interventions utilizing low-inten\-sity ultrasound (LIUS) exhibit substantial potential for hindering the proliferation of cancer stem cells. This investigation introduces a multiscale model and computational framework…

Analysis of PDEs · Mathematics 2024-02-16 B. Blanco , R. Palma , M. Hurtado , G. JimÉnez , C. GriÑÁn-LisÓn , J. Melchor , J. A. Marchal , H. Gomez , G. Rus , J. Soler

High intensity focused ultrasound (HIFU) has many applications ranging from thermal ablation of cancer to hemostasis. Although focused ultrasound can seal a bleeding site, physical mechanisms of acoustic hemostasis are not fully understood…

Fluid Dynamics · Physics 2014-11-25 Maxim A. Solovchuk , Marc Thiriet , Tony W. H. Sheu

The influences of blood vessels and focused location on temperature distribution during high-intensity focused ultrasound (HIFU) ablation of liver tumors is studied. A three-dimensional acoustics-thermal-fluid coupling model is employed to…

Fluid Dynamics · Physics 2011-11-15 Maxim A. Solovchuk , Tony W. H. Sheu , Marc Thiriet , Win-Li Lin

We develop a multiphysics-based model to predict the response of localized tumors to combined-hyperthermia-radiotherapy (CHR) treatment. This procedure combines hyperthermia (tumor heating) with standard radiotherapy to improve efficacy of…

Tissues and Organs · Quantitative Biology 2019-07-05 Japan K. Patel , Richard Vasques , Barry D. Ganapol

Conventional imaging of diagnostic ultrasound is widely used. Although it makes the differences in the soft tissues echogenicities' apparent and clear, it fails in describing and estimating the soft tissue mechanical properties. It cannot…

Medical Physics · Physics 2022-10-07 Hassan M. Ahmed

Timely diagnosis of breast cancer is an important task. This type of breast cancer is one of the most common diseases. The method of microwave radiothermometry is a promising direction for solving this problem. The method is based on…

Medical Physics · Physics 2023-08-08 Maxim Polyakov

It is proposed to treat cancer by the combination of a strong magnetic field with intense ultrasound. At the low electrical conductivity of tissue the magnetic field is not frozen into the tissue, and oscillates against the tissue which is…

General Physics · Physics 2009-06-04 Dr. Friedwardt Winterberg

Since decades, many techniques have been developed for curing cancer. Here, an effort has been made to cure tumor by inserting a cryoprobe into the target region which is connected to a cryogenic mechanism. This technique is presently used…

Medical Physics · Physics 2022-12-23 G Sai Krishna , Anup Paul

A simplified 2-D model which is an example of regional RF hyperthermia is presented. Human body is inside the wire with exciting current and the electromagnetic energy is concentrated within the tumor. The analyzed model is therefore a…

Medical Physics · Physics 2017-10-31 Piotr Gas

In the end of the second decade of 20th century, Warburg showed how cancer cells present a fermentative respiration process, related to a metabolic injury. Here, we develop an analysis of the cell process based on its heat outflow, in order…

Cell Behavior · Quantitative Biology 2021-07-27 Umberto Lucia , Giulia Grisolia

Contactless ultrasound power transfer (UPT) has emerged as one of the promising techniques for wireless power transfer. Physical processes supporting UPT include the vibrations at a transmitting/acoustic source element, acoustic wave…

Applied Physics · Physics 2020-10-09 Aarushi Bhargava , Shima Shahab

Induction of thermal damage to tissue through delivery of microwave energy is frequently applied in surgery to destroy diseased tissue such as cancer cells. Minimization of unwanted harm to healthy tissue is still achieved subjectively, and…

We report a model for hyperthermia therapies based on heat diffusion in a biological tissue containing a topological defect. Biological tissues behave like active liquid crystals with the presence of topological defects which are likely to…

Statistical Mechanics · Physics 2024-10-02 Andy Manapany , Loriane Didier , Leïla Moueddene , Bertrand Berche , Sébastien Fumeron

Non-invasive therapeutic ultrasound methods, such as high-intensity focused ultrasound (HIFU), have limited access to tissue targets shadowed by bones or presence of gas. This study demonstrates that an ultrasonically actuated medical…

Medical Physics · Physics 2022-07-20 Emanuele Perra , Nick Hayward , Kenneth P. H. Pritzker , Heikki J. Nieminen

Therapeutic ultrasound is an investigational modality which could potentially be used for minimally invasive treatment of prostate cancer. Computational simulations were used to study the effect of natural physiological variations in tissue…

Medical Physics · Physics 2018-11-08 Visa Suomi , Bradley Treeby , Jiri Jaros , Jani Saunavaara , Aida Kiviniemi , Roberto Blanco
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