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The form and evolution of multi-phase biomembranes is of fundamental importance in order to understand living systems. In order to describe these membranes, we consider a mathematical model based on a Canham--Helfrich--Evans two-phase…

Numerical Analysis · Mathematics 2021-07-20 Harald Garcke , Robert Nürnberg

A finite element method for the evolution of a two-phase membrane in a sharp interface formulation is introduced. The evolution equations are given as an $L^2$--gradient flow of an energy involving an elastic bending energy and a line…

Numerical Analysis · Mathematics 2019-11-01 John W. Barrett , Harald Garcke , Robert Nürnberg

We consider two-phase fluid deformable surfaces as model systems for biomembranes. Such surfaces are modeled by incompressible surface Navier-Stokes-Cahn-Hilliard-like equations with bending forces. We derive this model using the…

Numerical Analysis · Mathematics 2023-08-03 Elena Bachini , Veit Krause , Ingo Nitschke , Axel Voigt

In this work, we study a phase-field model for curvature-driven pattern formation in biomembranes. The model is derived as a gradient flow of an energy functional that approximates the two-phase Canham--Helfrich energy. This leads to a…

Analysis of PDEs · Mathematics 2025-11-27 Patrik Knopf , Anastasija Pešić , Dennis Trautwein

The Cahn--Hilliard equation is a widely used model that describes amongst others phase separation processes of binary mixtures or two-phase flows. In the recent years, different types of boundary conditions for the Cahn--Hilliard equation…

Numerical Analysis · Mathematics 2021-03-04 Stefan Metzger

In this paper, we study a hydrodynamic phase-field system modeling the deformation of functionalized membranes in incompressible viscous fluids. The governing PDE system consists of the Navier-Stokes equations coupled with a convective…

Analysis of PDEs · Mathematics 2022-06-22 Hao Wu , Yuchen Yang

We focus on the derivation and analysis of a model for multi-component phase separation occurring on biological membranes, inspired by observations of lipid raft formation. The model integrates local membrane composition with local membrane…

Analysis of PDEs · Mathematics 2025-07-08 Diogo Caetano , Charles M. Elliott , Maurizio Grasselli , Andrea Poiatti

Multicomponent bilayer structures arise as the ubiquitous plasma membrane in cellular biology and as blends of amphiphilic copolymers used in electrolyte membranes, drug delivery, and emulsion stabilization within the context of synthetic…

Analysis of PDEs · Mathematics 2015-12-22 Keith Promislow , Qiliang Wu

We present a numerical method to model the dynamics of inextensible biomembranes in a quasi-Newtonian incompressible flow, which better describes hemorheology in the small vasculature. We consider a level set model for the fluid-membrane…

General Mathematics · Mathematics 2023-05-30 Aymen Laadhari , Ahmad Deeb

We propose a new numerical method to solve the Cahn-Hilliard equation coupled with non-linear wetting boundary conditions. We show that the method is mass-conservative and that the discrete solution satisfies a discrete energy law similar…

Numerical Analysis · Mathematics 2019-10-21 B. Aymard , U. Vaes , M. Pradas , S. Kalliadasis

We present a parametric finite element approximation of two-phase flow. This free boundary problem is given by the Navier--Stokes equations in the two phases, which are coupled via jump conditions across the interface. Using a novel…

Numerical Analysis · Mathematics 2015-06-02 John W. Barrett , Harald Garcke , Robert Nürnberg

In this paper we study semi-discrete and fully discrete evolving surface finite element schemes for the Cahn-Hilliard equation with a logarithmic potential. Specifically we consider linear finite elements discretising space and backward…

Numerical Analysis · Mathematics 2025-09-11 Charles M. Elliott , Thomas Sales

Correctly formulated continuum models for lipid-bilayer membranes present a significant challenge to computational mechanics. In particular, the mid-surface behavior is that of a 2-dimensional fluid, while the membrane resists bending much…

Soft Condensed Matter · Physics 2017-03-08 Siming Zhao , Timothy Healey , Qingdu Li

We present a 2D parallel implementation of the modified Cahn-Hilliard equation for the simulation of a biofilm in an aqueous enviroment. Biofilms are attached microbial communities made of many different components and can have both…

Numerical Analysis · Mathematics 2018-11-30 Nathan McClanahan , Nicholas Stegmeier , Rylee Sundermann , Jeffrey Doom , Jung-Han Kimn

Consider a homogenous fluid membrane, or vesicle, described by the Helfrich-Canham energy, quadratic in the mean curvature. When the membrane is axially symmetric, this energy can be viewed as an `action' describing the motion of a…

Soft Condensed Matter · Physics 2009-11-11 Riccardo Capovilla , Jemal Guven , Efrain Rojas

The paper considers a thermodynamically consistent phase-field model of a two-phase flow of incompressible viscous fluids. The model allows for a non-linear dependence of fluid density on the phase-field order parameter. Driven by…

Numerical Analysis · Mathematics 2023-09-27 Yerbol Palzhanov , Alexander Zhiliakov , Annalisa Quaini , Maxim Olshanskii

The paper presents a complete research cycle comprising continuum-based modeling, computational framework development, and validation setup to predict phase separation and surface hydrodynamics in lipid bilayer membranes. We starting with…

Numerical Analysis · Mathematics 2025-10-14 Maxim Olshanskii , Annalisa Quaini

The Cahn--Hilliard equations are a versatile model for describing the evolution of complex morphologies. In this paper we present a computational pipeline for the numerical solution of a ternary phase-field model for describing the…

A phase-field model that takes into account the bending energy of fluid vesicles is presented. The Canham-Helfrich model is derived in the sharp-interface limit. A dynamic equation for the phase-field has been solved numerically to find…

Soft Condensed Matter · Physics 2007-05-23 F. Campelo , A. Hernandez-Machado

We show existence and uniqueness of strong solutions to a Navier-Stokes/Cahn-Hilliard type system on a given two-dimensional evolving surface in the case of different densities and a singular (logarithmic) potential. The system describes a…

Analysis of PDEs · Mathematics 2024-08-15 Helmut Abels , Harald Garcke , Andrea Poiatti
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